Dorkmo

"universal vaccine platform" This will be a slow thread of random stuff I come across in regards to research in the years before SARS2

@jarikuikanmaki Same day

@Robotbeat currently boiling the ocean for custom LoRa firmware for long distance remove control of farm equipment. github copilot recently implemented weekly rate limits on usage so they wont even let me use as much i would like to github.com/OpenSourceEcol…

I honestly don’t know how you guys are using up all your tokens. I’m given like $300 worth of tokens per month and I have no idea how I will get even close to using that much.

@Rebecca21951651 Pretty sad that he thinks fraudulent analysis and propaganda are DATA

Fucking moron talks down to others thinking they aren't scientists....

@ProfKlase @Rebecca21951651 iT wAsNt FuNdEd

@Rebecca21951651 @Rebecca21951651 apparently hasn't even read the paper they attack as their only leverage. We're done. Bring DATA for a lab origin. Not circles, not guesses, not coincidence, data.

"We scientists" didn't work with data in Proximal Origins.

This Jan, I wrote to @NIH @NIHDirector_Jay with @SenJoniErnst w/concerns about the Rocky Mountain Lab’s bat research w/viruses like Ebola & its ties 2 Wuhan and EcoHealth Alliance. Unfortunately, he defended it. This explosive whistleblower report from my friends at @WhiteCoatWaste is more ammo 4 why Congress should cut all funding 4 all Fauci-era programs in the upcoming FY27 NIH spending bill, as I've proposed.

@ModeratorGage @bigta

When it comes to 3D printing you don't see many shotguns. If you've been following us for a bit you know about the Dirte Dozen. Coming in single shot or double barrel this beautiful break action is an absolute beast. It utilizes a printed body, and all hardware store parts. Everything from the screws, to the diy firing pins, triggers, hammers, plates, etc can be made at home. Want to join the team making this possible? Come and join the Black Lotus Coalition.

Reminder: Baric's career started with SARS1 at Fort Detrick Stalking SARS: Twenty years ago, Ralph Baric quietly began studying coronaviruses. Now he’s battling a global menace. In the struggle of human against virus, it pays to be prepared. September 1, 2003 In early June 2003, after months of press conferences and university lectures stressing vigilance to the emerging global SARS epidemic, North Carolina’s state epidemiologists and UNC Hospitals staff had reason to mobilize. A contract UNC-Chapel Hill employee, having visited a sick relative in a tainted Toronto hospital, came down with severe acute respiratory syndrome while on the job. State health officials quarantined the man’s coworkers, caregivers, and family in a successful effort to control the infection. At the same moment, though, Ralph Baric, professor of epidemiology and microbiology and immunology, was doing the opposite. He was figuring out ways to make more of the deadly virus by rebuilding it from the bottom up. But he’s no rogue scientist. Baric was attempting to create an infectious clone of the urbani strain of the SARS coronavirus. By July he had successfully tested — at the Army’s top bio-level three labs in Maryland — his cloning approach, which could lead to a SARS vaccine and less of the deadly disease. “It is nice to be positioned to respond to a potentially important human problem,” Baric says. His SARS clone will allow other researchers around the world to produce other mutated SARS coronaviruses in an attempt to find one that the human body could tolerate enough to produce antibodies. (Baric is also an expert in Norwalk viruses, the pathogen that has caused widespread illness among cruise-ship passengers.) For twenty-one years Baric has studied coronaviridae, a family of viruses that causes 15 to 30 percent of our common colds and devastates swine, cattle, cats, and lab rats with severe illnesses. Coronaviruses, with their protein envelope and halo of spikes, are the most complex of the positive-stranded RNA viruses. RNA viruses replicate in the cytoplasm of the host cell independent of the cell’s nucleus. The coronavirus replication strategy is unique, Baric says, and in 1982 he thought it would become an exciting field of virology. But a year later, HIV emerged, and the world’s attention turned to the human immunodeficiency virus. Even so, Baric kept his focus. Normally jocular, Baric now has more reason to smile — he was right all along. “A lot of my research pointed to the fact that new coronaviruses had the high potential to emerge and cause significant disease,” Baric says. He published a paper in 1995 suggesting that danger. “His predictions came true in remarkably short time,” says Mark Denison, a physician at Vanderbilt University Medical Center who has known Baric for fifteen years and is currently collaborating with him on two coronavirus studies. What makes a coronavirus so serious, Baric says, is its high rate of recombination and mutation, a constant genome shifting that gives viruses abilities to efficiently replicate and to evade animal immune defenses. With increasing population densities and ecological change, we’re becoming exposed to more exotic animals and the viruses they harbor. The civet cat and other species found in the live-animal markets of China have been implicated in the transmission of the SARS coronavirus to humans. Baric is an expert in the study of cross-species transmission. As he studied the way coronaviruses move from one species to another, he found that the viruses become more prolific. “They become generalists,” adapting to multiple species at the same time, he says. Mouse hepatitis virus, for example, adapts to humans just as easily as it does to hamsters and primates. Then, once a virus is comfortable in a particular species, he says, it probably evolves into a specialist, developing a more efficient replication and transmission strategy for that specific animal. Over the past decade, several new coronavirus pathogens emerged in pigs and cows. These viruses spread globally and within a few years of emergence caused considerable economic loss in the United States and elsewhere. Baric is the only U.S. researcher who’s been able to clone any of the coronaviruses, which had eluded laboratory manipulation for many years. He and his students, including Boyd Yount and Kristopher Curtis, developed a method to reproduce multiple viruses, break their genomes into fragments that could be genetically manipulated, and then patch pieces of each into a full-length clone from which molecularly cloned viruses could be recreated in the laboratory. It was a profound approach, Denison says, and one that has dramatic implications for how scientists study coronaviruses. Susan Baker, a virologist at Loyola University Chicago, agrees. “Ralph’s work on the systematic assembly of a full-length infectious cDNA of coronaviruses — first for the porcine coronavirus and then for the murine coronavirus — produced landmark studies,” Baker says. She praises Baric for sharing the clones with other researchers, who use his creations to put specific mutations back into the genetic information of the virus to learn if the mutations have any effect on virus replication. The global focus on SARS, and the scientific community’s interest in Baric’s work, meant he was able to persuade university officials to convert an unused bio-level three laboratory into a coronavirus lab. And this summer, the National Institutes of Health shoved money Baric’s way to support his efforts to produce the infectious SARS coronavirus clone. Within a few years, this clone could lead to an attenuated virus — a live SARS virus that has been tweaked so it’s no longer deadly. That, in turn, could be used to create an effective vaccine. Baric’s dedication to understanding the minute details of coronaviruses has made him a “go-to guy” that other virologists respect, says Curtis, a recent doctoral student mentored by Baric. “There’s nobody in the field that I respect more,” Denison says. “Ralph deserves a tremendous amount of credit for his work.” Indeed, Baric was quickly invited to participate in the important weekly SARS teleconferences convened by the Centers for Disease Control and Prevention in May and June. By August the world health community had beaten back SARS and learned a valuable lesson. “The SARS coronavirus illustrates that even supposedly benign viral pathogens have considerable potential to evolve and cause significant disease,” Baric says. “And really what that means is basic research in all virus families — even those that don’t seem to be important pathogens — has the potential to have big payoffs.” Baric has multiple grants from the National Institutes of Health to study Norwalk viruses and coronaviruses. endeavors.unc.edu/fall2003/baric…

@ProGof39474 It's time to earn your keep.

Guys, really rough day in virology lawyering and PR. Thoughts and prayers, and if you need me I'll be doing Sauna with Jon Cohen.

@AGCast4 AG is CIA spy confirmed

AG lore drop but I had the chance to do a study abroad at the Wuhan Institute of Virology in the summer of 2020. It was to help with research on “emerging diseases.”It got cancelled if you can believe it

How @ScienceMagazine loses trust -- banning comments on this ONE post. Why would that be? @sudipsparikh @aaas @AAAS_GR @AAAS_SciComm

USAID funds were used to generate a novel merbecovirus genome sequence from S.China. This was used by the WIV to create a highly risky dGOF chimera by inserting the MERS spike gene into the novel merbecovirus backbone For details see: zenodo.org/records/189452…

US Director of National Intelligence is to review funding for more than 120 US-backed biolabs abroad, including over 40 in #Ukraine (previously denied by Biden), to assess pathogens & research activities. Clinical trials in these labs raise serious ethical & financial questions.

The last few days have been somewhat remarkable in terms of accountability on COVID origins, the cover up, and the broader issue of dangerous pathogen research. - David Morens was indicted for concealing key documents and conspiring with EHA. - Ralph Baric was served a Notice of Suspension and Proposed Debarment. - Tulsi Gabbard is investigating US-funded biolabs in more than 30 countries. - A CIA whistleblower now says Fauci influenced the Agency’s assessment, despite most CIA scientists concluding the virus came from a lab. These are the absolute low-hanging fruits. What the public actually needs is the underlying studies, analyses, and intelligence that drove IC's lab origin assessment. If the whistleblower is right, some of that material may already be sitting on Gabbard’s desk awaiting release, and hopefully, it sees daylight soon. But Morens could not have run a multi-year scheme to dodge FOIA and transparency laws on his own, without it being known at least at some higher level. And there is already evidence that Fauci organised the "Proximal Origin" paper outside official channels, communicated through a private Gmail account, and worked to shield Daszak and EHA - all points raised in Morens’ own emails. Why is he still untouched? Then there’s Francis Collins, the man who directed the gain-of-function research policies, relaxed it's scope, and is on record discussing ways to "put down" what he called a "very destructive conspiracy," and hoping that Proximal Origin paper would settle it. Why is Collins rarely mentioned when accountability is discussed? Daszak was debarred from federal funding, but that’s about it. Much of his EHA team, along with partners at USAID and elsewhere haven't even been scrutinized more closely. Same goes for the Proximal Origin authors and other conflicted scientists and officials. Somehow they still get to keep their jobs. If this were some routine police investigation, the evidence already in public view would be enough to serve court warrants, and justify a far more aggressive inquiry. Instead, years later, groups like @USRightToKnow are still fighting in courts, lawsuits after lawsuits, for scraps of information. Yes, we are far from where things stood a few years ago. But it's wild that while the Trump admin has publicly embraced lab origin yet simultaneously treats it like a minor inconvenience, throwing up just a flashy website and some headlines instead of delivering any real accountability and reform. No serious guardrails or regulations have been put in place to stop this from happening again. No meaningful transparency reforms. No robust oversight framework for high-risk pathogen research. And, almost no one of real significance has been held meaningfully accountable. Time matters here. Documents go missing. Custody changes hands. Memories fade and the context erodes with time. And the clock is ticking.

CIA whistleblower alleges COVID lab-leak findings were suppressed by agency. Via @lewiskamb @USRightToKnow usrtk.org/covid-19-origi…

@hunterlanier @ltgiv

Software: if anybody finds out my first name, my whole life is compromised Hardware: Hey dude! I’m Jake from Little Rock Arkansas, 731 Winchester Ave. 38546 you can just pop by whenever you want! I have beer if you are friendly but if not I will feed you to the hogs

This closed circle was discussed in the hearing today: Scientists get funding for Gain of Function research from US gov. US gov funded GoF research in Wuhan starts a pandemic. US gov needs to find subject matter experts to inform the gov on the likelihood GoF research led to the pandemic. Unbiased assessment by scientists is, sure is possible/likely it came from a lab. Scientists meet with US gov research funding source guy and then they change their tune; lab leak impossible. US gov research funding source guy does 2 things: -increases research funding to these change of heart scientists and, - recommends to the US gov these change of heart scientists be used as experts to help with the assessment of the likelihood of the natural or lab origin of the pandemic. US gov subject matter analysts try to write reports on likely lab origin but higher ups in IC, working at night, squash their work. US gov concludes it could not have come from a lab after these 'twister-level' contortions. A circle of untruthfulness. hsgac.senate.gov/hearings/whist…

In light of today’s whistleblower testimony that Fauci was aggressively pushing his fraudulent Proximal Origin authors into the intelligence community to seed the false natural origin narrative, all while pretending not to know who the authors were, here is an email from lead author Kristian Andersen thanking Fauci for his “advice and leadership as we worked through the SARS-CoV-2 ‘origins’ paper.” Of course, all of this has been publicly known since June 2021 and absolutely nothing has been done about it. But at the very least, the historical record should reflect the truth. Fauci funded and facilitated the creation of Covid and then, when it all went bad, he orchestrated the world’s most devastating cover up.

@TylerAStepke But a savior to The Science

If Andersen lied about the possibility of lab origin to the US IC in the same way he lied to the public, he needs to face consequences. He attempted to delete early C19 seqs, and clearly committed fraud in PO. He's a serious threat to global biosecurity and US national security.

There was no law to "declassify all the covid information". As I reported at the time, "Contrary to the claims of Sen. Hawley and other sponsors, the legislation only instructs the DNI to release information relating to the Wuhan Institute of Virology. No examination of others." husseini.substack.com/p/senate-did-n…

@ProGof39474 @stevenemassey Fauci's own Institut Pasteur

@stevenemassey Pandemics Without Borders.

Isn't Lipkin the *only* American proximal boy?