Adrianne Stone 👩🏻‍💻🚀🍻

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Adrianne Stone 👩🏻‍💻🚀🍻

Adrianne Stone 👩🏻‍💻🚀🍻

@dradriannestone

Product @bigcartel | host Houston startup happy hours | fmr product 23andMe, Bount, AirDev | Biomedical PhD

RSVP for happy hour 👉 Katılım Mart 2009
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Danny
Danny@shipscode·
@washghost1 Bad behavior as a married man. But the societal double standard is wild. Dancing with lady = bad Leaving your husband for dancing with lady = good Not to mention embarrassing your husband infront of his kids & world online. Then they get angry men don't want to commit.
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Adrianne Stone 👩🏻‍💻🚀🍻
I’m going to assume best intent here - we don’t know. There was a rush to declare this a zoonotic spillover and a silencing of dissent for political reasons, not the least of which being Fauci had funded govt grants for the kind of gain of function research on bat coronavirus that Wuhan was doing. Also complicated by the fact that this happened in China so we will never get a straight answer out of them. Evidence against zoonotic spillover: - There are no intermediate hosts or direct animals matches - there is no direct match to existing animal viruses - furin cleavage site on the spike protein (drives infectiousness) doesn’t exist in wild type covid virus China has hidden evidence from the earliest infections and only turned over partial datasets on early samples making it hard to know conclusively
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Conor Friedersdorf
Conor Friedersdorf@conor64·
A question for everyone: survey data suggests that by the end of the Covid-19 emergency trust in public health institutions had decreased significantly. If you are among the people who reacted that way, why specifically? I'm hoping for long, diverse, individualized answers.
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Patrick Collison
Patrick Collison@patrickc·
Oh, reflexive dismissal of lab leak theories should also be on the list, of course. I can’t readily think of a profession that declined more in my estimation over the past 10 years than public health. Like most, I started out with a very favorable view—one of brave and far-sighted technocrats—informed by movies like “Contagion”.
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Cat Knows Nothing
Cat Knows Nothing@CatKnowsNth·
The face carrying 47 years of uncle wisdom
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Aakash Gupta
Aakash Gupta@aakashgupta·
OpenAI just exited the video generation business entirely. App dead. API dead. No video inside ChatGPT. Disney’s $1 billion deal, signed four months ago, is dead. Read that again. This isn’t a consolidation into the super app. Altman told staff Tuesday that OpenAI is winding down all products using video models. Disney’s own statement says they respect OpenAI’s decision to “exit the video generation business.” The Sora research team is being redirected to robotics. The reason is sitting right there in the competitive data. Anthropic hit $19 billion in annualized revenue by early 2026 selling text and code. No video generation. No image generation. No consumer social app. No Disney deal. One product surface: chat, code, computer use, all in one place. OpenAI looked at where every dollar of market growth was coming from and saw the answer: coding and enterprise. So now they’re copying the model. ChatGPT, Codex, and the browser merge into one app. Instant Checkout killed today too. Every consumer experiment is getting cut. What remains is the Anthropic playbook: one app, code and chat, enterprise and developer focus. The Sora numbers explain the urgency. Total consumer revenue across iOS and Android since September: $1.4 million. Peak month was $540,000. Every video generation burned GPU compute that could have been running inference for ChatGPT or Codex instead. OpenAI’s own head of Sora announced generation limits because chips couldn’t keep up. At $14 billion in projected 2026 losses, every GPU matters. Google just inherited the AI video market by default. Nano Banana already lives inside Gemini. No standalone app to manage, no separate brand to support. Among the majors, they’re the only ones left. Runway, Kling, Minimax, Luma, and the other independents are still shipping, but none of them have Google’s distribution. Disney put $1 billion in stock warrants on a product that lasted six months. The deal was announced in December. Characters from Marvel, Pixar, and Star Wars were supposed to be generating fan videos on Sora by now. Instead, Disney is writing a polite press statement about “respecting OpenAI’s decision” while its legal team unwinds a deal that never produced a single licensed video. Four months from billion-dollar partnership to obituary. That’s how fast the AI product landscape reprices when the unit economics don’t work.
Sora@soraofficialapp

We’re saying goodbye to the Sora app. To everyone who created with Sora, shared it, and built community around it: thank you. What you made with Sora mattered, and we know this news is disappointing. We’ll share more soon, including timelines for the app and API and details on preserving your work. – The Sora Team

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United Airlines
United Airlines@united·
The entire row is alllllll yours. Welcome to United Relax Row, three adjacent United Economy seats with adjustable leg rests that can each be raised or lowered to create a cozy lie-flat space for stretching out... You'll also get a mattress pad, blanket and two pillows. If you’re traveling with kids, a plushie too! United Relax Row will be available starting next year on more than 200 of our 787s and 777s, each with up to 12 of these brand-new rows. united.com/Elevated
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Claude
Claude@claudeai·
You can now enable Claude to use your computer to complete tasks. It opens your apps, navigates your browser, fills in spreadsheets—anything you'd do sitting at your desk. Research preview in Claude Cowork and Claude Code, macOS only.
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Ihtesham Ali
Ihtesham Ali@ihtesham2005·
I spotted a lawyer recently at a big law firm doing something on his laptop between depositions. Took me a second to realize what I was looking at. He had NotebookLM open with 6 years of case files uploaded. Here's what he was actually doing. I watched him paste in a fresh deposition transcript and run one prompt: "Cross-reference this testimony against all prior statements in this case and flag every contradiction with exact page citations." What used to take a paralegal team 2 days came back in 90 seconds. But that wasn't the part that broke my brain. He uploads every opposing counsel's past filings into a separate notebook. Then asks: "What argumentation patterns does this attorney rely on and where have those arguments failed in court before?" He walks into every hearing already knowing how the other side thinks. I asked him how long he'd been doing this. "Since I realized billing hours for document review was making me dumber." His win rate in summary judgment motions is up. His prep time is down 60%. His partners think he just got sharper with experience. He told me the experience part is true. He just has a 6-year memory that never forgets a page number.
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Simon
Simon@HoustonHizzoner·
@mattyglesias Democrats don’t get to pick and choose what to fund.
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Gandalv
Gandalv@Microinteracti1·
Robert Mueller died last night. He was 81 years old. He had a wife who loved him for sixty years. He had two daughters, one of whom he met for the first time in Hawaii, in 1969, on a few hours of military leave, before he got back on the plane and returned to Vietnam. He had grandchildren. He had a faith he practiced quietly, without performance. He had, in the way of men who have seen real things and survived them, a quality that is increasingly rare and increasingly mocked in the country he spent his life serving. He had integrity. And tonight the President of the United States said good! I have been sitting with that word for hours now. Good. One syllable. The thing you say when the coffee is hot or the traffic is moving. The thing a man who has never had to bury anyone, never had to sit in the specific silence of a room where someone is newly absent, reaches for when he wants the world to know he is satisfied. Good. The daughters are crying and the wife is alone in the house and good. I want to speak directly to the Americans reading this. Not the political Americans. Just the human ones. The ones who have lost a father. The ones who know what it is to be in that first hour, when you keep forgetting and then remembering again, when ordinary objects become unbearable, when the world outside the window seems obscene in its indifference. I want to ask you, simply, to hold that feeling for a moment, and then to understand that the man you elected looked at it and typed a single word. Good. This is not a country having a bad day. I need you to understand that. Countries have bad days. Elections go wrong. Leaders disappoint. Institutions bend. But there is a different thing, a rarer and more terrible thing, that happens when the moral center of a place simply gives way. Not dramatically. Not with a single catastrophic event. But quietly, in increments, until one evening a president celebrates the death of an old man whose family is still warm with grief, and enough people find it acceptable that it becomes the weather. Just the weather. That is what is happening. That is what has happened. The world knows. From Tokyo to Oslo, from London to Buenos Aires, people are not angry at America tonight. Anger would mean there was still something to fight for, some remaining faith to be betrayed. What I see, in the reactions from everywhere that is not here, is something older and sadder than anger. It is the look people get when they have waited a long time for someone they love to find their way back, and have finally understood that they are not coming. America is being grieved. Past tense, almost. The idea of it. The thing it represented to people who had nothing else to believe in, who came here with everything they owned in a single bag because they had heard, somehow, across an ocean, that this was the place where decency was written into the walls. That idea is not resting. It is not suspended. It is being buried, in real time, with 7,450 likes before dinner. And the church said nothing. Seventy million people have decided that this man, this specific man who has cheated everyone he has ever made a promise to, who has mocked the disabled and the dead and the grieving, who celebrated tonight while a family wept, is an instrument of God. The pastors who made that bargain did not just trade away their credibility. They traded away the thing that made them worth listening to in the first place. The cross they carry now is a costume. The faith they preach is a loyalty oath with scripture attached. When the history of American Christianity is written, this will be the chapter they skip at seminary. Now I want to talk about the men who stand next to him. Because this is the part that actually breaks my heart. JD Vance is not a bad man. I have to say that, because it is true, and because the truth matters even now, especially now. Marco Rubio is not a bad man. Lindsey Graham is not a bad man. They are idiots, but not bad, as in BAD! These are men with mothers who raised them and children who love them and friends who remember who they were before all of this. They are not monsters. Monsters are simple. Monsters do not cost you anything emotionally because there is nothing in them to mourn. These men are something more painful than monsters. They are men who knew better, and know better still, and will get up tomorrow and do it again. Every small compromise they made had a reason. Every moment they looked the other way had a justification that sounded, at the time, almost reasonable. And now they have arrived here, at a place where a president celebrates the death of an old man and they will find a way, on television, to say nothing that means anything, and they will go home to houses where children who carry their name are waiting, and they will say goodnight, and they will say nothing. Their oldest friends are watching. The ones who knew Rubio when he still believed in something. Who knew Graham when he said, out loud, on the record, that this exact man would destroy the Republican Party and deserve it. Who sat next to Vance and thought here is someone worth knowing. Those friends are not angry tonight. They moved through anger a long time ago. What they feel now is the quiet, irrecoverable sadness of watching someone disappear while still being present. Of watching a person they loved choose, again and again, to become less. That is what cowardice costs. Not the coward. The people who loved him. And in the comments tonight, the followers celebrate. People who ten years ago brought casseroles to grieving neighbours. Who stood in the rain at gravesides and meant the words they said. Who told their children that we do not speak ill of the dead because the dead were someone's beloved. Those people are tonight typing gleeful things about a man whose daughters are not yet done crying. And they feel clean doing it. Righteous. Because somewhere along the way the thing they were given in exchange for their decency was the feeling of belonging to something, and that feeling is very hard to give up even when you can no longer remember what you gave for it. When Trump is gone, they will still be here. Standing in the silence where the noise used to be. Without the permission the crowd gave them. Without the pastor who told them their cruelty was holy. They will be alone with what they said and what they cheered and what they chose to become, and there will be no one left to tell them it was righteous. That morning is coming. Robert Mueller flew across the Pacific on military leave to hold his newborn daughter for a few hours before returning to the war. He came home. He buried his dead with honour. He served presidents of both parties because he understood that the institution was larger than any one man. He told his grandchildren that a lie is the worst thing a person can do, that a reputation once lost cannot be recovered, and he lived that, every day, in the quiet and unglamorous way of people who actually believe what they say. He was the kind of American the world used to point to when it needed to believe the story was true. He died last night. His wife is alone in their house in Georgetown. His daughters are learning what the world is without him in it. And somewhere in the particular hush that falls over a family in the first hours of loss, the most powerful man and the biggest loser on earth sent a message to say he was glad. The world that loved what America was supposed to be is grieving tonight. Not for Robert Mueller only. For the country that produced him and then became this. For the distance between what was promised and what was delivered. For the suspicion, growing quieter and more certain with each passing month, that the America people believed in was always partly a story, and the story is over now, and there is nothing yet to replace it. That is all it needed to be. A man died. His family is broken open with grief. That is all it needed to be. Instead the President said good. And the country that once stood for something looked away 🇺🇸 Gandalv / @Microinteracti1
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James Talarico
James Talarico@jamestalarico·
The President of the United States said I insulted Jesus. You want to know what insults Jesus? Kicking the sick off their healthcare. Bombing schoolchildren in Iran. Deporting moms and babies. Covering up the Epstein files.
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Adrianne Stone 👩🏻‍💻🚀🍻
@M_M_MacFadyen @shanaka86 Exactly. Factory farming is a scourge and clearly a national security risk if it is as easily disrupted as this (though others in the thread disagree, let’s say for the sake of argument this effect is felt in 1.5-2 years instead of this year)
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Margot Maddison-MacFadyen, PhD
Margot Maddison-MacFadyen, PhD@M_M_MacFadyen·
In the olden days before tractors and chemical fertilizers there was manure. Livestock produced the manure. Grass was needed for the livestock—cows, sheep, horses. Oxen and horses pulled the plows. Maybe that was a better way? The transition happened in less than a lifetime. Maybe 60 years ago. Can we press reset?
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Shanaka Anslem Perera ⚡
Shanaka Anslem Perera ⚡@shanaka86·
JUST IN: The most irreversible consequence of this war is not happening in Tehran. It is happening in a barn in Iowa. A farmer is standing over a kitchen table looking at two seed catalogues. One is corn. One is soybeans. Corn needs 180 pounds of nitrogen per acre. Nitrogen costs $610 per ton on the CBOT March futures settlement as of yesterday, up 35 percent in a month. Soybeans fix their own nitrogen from the atmosphere through root bacteria called rhizobia. They need nothing from the Strait of Hormuz. The farmer is choosing soybeans. Millions of acres are choosing soybeans. And once the planter rolls into the field, the choice cannot be reversed until next year. USDA projected corn at roughly 94 million acres for 2026, down from 98.8 million. Soybeans at 85 million, up from 81.2 million. Those projections were published February 19, before urea surged past $683 at New Orleans. The actual shift will be larger. USDA Prospective Plantings reports March 31. By then the seeds will be in the ground. This is the transmission channel the world is not watching. A 21-mile strait enforced by provincial commanders with sealed radio orders just rewrote the planting economics of 90 million acres of the most productive farmland on Earth. Not through sanctions. Not through diplomacy. Through the price of a single molecule that corn cannot grow without and soybeans do not need. Now follow the cascade. The Renewable Fuel Standard mandates 15 billion gallons of corn ethanol annually. That consumes roughly 43 percent of the entire US corn crop. The mandate is set by the EPA. It does not flex when corn acres shrink. It is inelastic demand consuming a fixed share of a declining supply. When supply tightens against a fixed mandate, the remaining corn reprices upward. Corn above $5 per bushel compresses every margin downstream. The US cattle herd stands at 86.2 million head, a 75-year low per USDA NASS. Poultry and pork operations face compression from higher corn prices. Feed is the single largest cost in livestock production. When feed reprices, protein reprices. When protein reprices, every grocery shelf in America absorbs the increase. This is the protein cascade. Corn to feed to meat to eggs to dairy to the checkout counter. Each link tightens because the link before it tightened. The originating cause is a urea molecule that cannot transit a strait because a provincial commander’s sealed orders say it cannot. The farmer did not start this war. The farmer cannot end it. The farmer responds to the price on the screen and the biology of the two crops in front of him. Corn needs the molecule. Soybeans do not. At $610 the arithmetic is settled. The planter rolls. The season is locked. Israel just authorised the assassination of every Iranian official on sight. The US has spent $16.5 billion. South Pars is burning. The Fed is holding rates because oil inflation will not break. Gold touched $5,000. Bitcoin is bleeding. China is running exercises near Taiwan. Sri Lanka shut down on Wednesdays. And underneath all of it, a man in a barn is making the decision that determines whether four billion people pay more for food this year. He has never heard of the Mosaic Doctrine. He does not know what a sealed contingency packet is. He knows what nitrogen costs. And he is planting soybeans. Full analysis - open.substack.com/pub/shanakaans…
Shanaka Anslem Perera ⚡ tweet media
Shanaka Anslem Perera ⚡@shanaka86

Right now, in barns and equipment sheds across the American Midwest, farmers are making the most consequential decision of this war. Not generals. Not senators. Farmers. At $683 per ton urea, corn economics have collapsed. Nitrogen is the single largest input cost for corn production. At pre-war prices a farmer could justify 180 pounds per acre and expect a margin. At $683 the math breaks. Soybeans fix their own nitrogen from the atmosphere through root bacteria. They do not need the molecule trapped behind the Strait of Hormuz. The seed decision is being made this week across roughly 90 million acres of American cropland. Once the planter rolls into the field, the choice is irreversible. Corn seed in the ground stays corn. Soy seed stays soy. The acreage allocation locks in. USDA Prospective Plantings reports March 31. That report will tell the world how American agriculture responded to the Hormuz blockade. But the decisions it captures are being made now, in conversations between farmers and agronomists and seed dealers who are looking at nitrogen prices and making the rational economic choice: plant the crop that does not need the input you cannot afford. Every acre that shifts from corn to soybeans tightens the corn balance sheet for the rest of the year. Corn feeds livestock. Corn feeds ethanol. The Renewable Fuel Standard mandates 15 billion gallons of corn ethanol annually, consuming roughly 43 percent of the US corn crop regardless of price. That demand is inelastic. If acres shift and production falls while the mandate holds, corn prices spike. Feed costs spike. The protein cascade reverses. The US cattle herd sits at 86.2 million head, a 75-year low. Poultry and pork margins that were benefiting from cheap feed compress when corn crosses $5 per bushel. This is how a naval blockade 7,000 miles from Iowa reaches the American grocery shelf. Not through oil. Not through shipping. Through nitrogen. The farmer cannot afford the molecule. The molecule cannot transit the strait. The farmer plants soy instead. The corn supply tightens. The ethanol mandate consumes its fixed share. The remaining corn reprices. The feed reprices. The meat reprices. The grocery bill reprices. The decision is not political. It is arithmetic performed on a kitchen table by a person who needs to plant in three weeks and cannot wait for a ceasefire, an escort convoy, or an insurance normalisation that the Red Sea precedent says takes years. The deepest penetrator in the American arsenal cannot reach a sealed Iranian doctrinal packet. But the fertiliser price it failed to resolve is reaching every planting decision on 90 million acres of the most productive farmland on Earth. The war’s most irreversible consequence is not happening in a bunker. It is happening in a barn. And by the time USDA publishes the data on March 31, the seeds will already be in the ground. Full analysis in the link. open.substack.com/pub/shanakaans…

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Greg Abbott
Greg Abbott@GregAbbott_TX·
That’s right. We don’t want school choice funds going to radical Islamic indoctrination with historic connections to terrorism. I signed laws banning Sharia cities. I designated CAIR and the Muslim Brotherhood as foreign terrorist organizations and transnational criminal organizations. And I will pass another law that completely bans Sharia Law in Texas. washingtonpost.com/education/2026…
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Adrianne Stone 👩🏻‍💻🚀🍻
@sarahmsachs This sounds like it would be an important role, especially as notion moves into more AI products, but the salary band on the JD would suggest otherwise. I’m a little surprised considering that a comfortable income starts at 135 in New York, and 150 in SF
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Sarah Sachs
Sarah Sachs@sarahmsachs·
New job title just dropped: Model Behavior Engineer. Your job: make AI behave. Prompts, evals, model selection, debugging weird outputs. basically owning the quality bar for AI products. this role literally didn’t exist a few years ago. We’re hiring → jobs.ashbyhq.com/notion/4bbfad8…
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Benjamin Verbeek
Benjamin Verbeek@benjaminvrbk·
lovable is free for everyone on sunday to celebrate international womens day & shebuilds <3 make my life harder by telling your friends best regards, weekend AI ops
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Adrianne Stone 👩🏻‍💻🚀🍻
@ShehanCoach @jamestalarico If God is sovereign, then our choices to act or to stay passive are both inside His sovereignty. His statement about ‘no other hands’ pushes against a lazy fatalism that hides behind theology. Omnipotence doesn’t excuse us from being God’s hands and feet. It removes our excuses.
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Coach Joe Shehan
Coach Joe Shehan@ShehanCoach·
What an incredibly small god you must serve if “god has no other hands but our hands”. My God is the sovereign, omnipotent, omniscient, omnipresent Creator of the Universe whose ways are not our ways and whose thoughts are not our thoughts. It is incredibly cynical to think He cannot soften and change the hearts of men and change a society towards peace.
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James Talarico
James Talarico@jamestalarico·
America is praying for Austin. But there is something profoundly cynical about asking God to solve a problem we're not willing to solve ourselves. God moves and works through us. God has no other hands but our hands. We must act.
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