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Happy to see our recent paper featured on the March cover of @NatImmunol ! Paper: nature.com/articles/s4159… Summary: nature.com/articles/s4159… @vytheofilou @CFI_UMN @UMNews @UMNCancer @NIAIDNews
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Drake Williams
173 posts
Drake Williams
@drake_dds
Scientist. Dad. Dentist. Leading LOMI @CFI_UMN using systems biology to understand oral barrier immunity. Views my own.
Minneapolis, MN Katılım Haziran 2017
118 Takip Edilen129 Takipçiler
@AndrsHidalgo16 Congratulations to you, your team, and collaborators!
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Today, we see the fruit of 5+ years of teamwork. We have built a map of the neutrophil compartment (mostly in mice - but also humans). It provides a biological structure that focuses on a single immune cell lineage to discover the many ways in which neutrophils to physiology.
Daniela Cerezo Wallis@danielacerezo
I’m thrilled to introduce you to the NeuMap! our latest work in @Nature. A global, comprehensive, single-cell transcriptional atlas of neutrophils across 47 biological conditions in human and mice. A real tour-de-force 🗺️ @AndrsHidalgo16 nature.com/articles/s4158…
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1/n Proud to share our latest work @NEJM. A long journey of integrated basic research and clinical care revealed a central role for IFN-g in driving mulitorgan autoimmunity in APECED and devised a personalized, life-transformative intervention for patients
nejm.org/doi/full/10.10…
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Drake Williams retweetledi
Drake Williams retweetledi
Epithelial-derived interleukin-23 promotes oral mucosal immunopathology dlvr.it/T5KF7S
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50 days free access link: authors.elsevier.com/c/1inso3qNrUxt…
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Check out the newest from Moutsopoulos lab
@NIDCR
led by the venerable Tae Sung in @ImmunityCP. Here, we find that flagellated microbes trigger epithelial-derived IL23 production which has pathogenic effects in the oral mucosa.
📰sciencedirect.com/science/articl…
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Happy to share my PhD work 🦴SHIP1 deficiency causes inflammation-dependent retardation in skeletal growth🦴is now online. Thanks to all people 🙏who made it happen @BoneBiology @PhilippeKrebs1 🏆
@unibern
LifeScienceAlliance@LSAjournal
Read this new study that highlights the important contribution of the immune system and inflammation to skeletal and bone development. Congrats to @Fatem3hSa @PhilippeKrebs1 and Willy Hofstetter @igmp_unibern @uniBern bit.ly/3uA0dCx
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Drake Williams retweetledi
How do different mutations in #UBA1 cause autoinflammatory #VEXAS syndrome, spinal muscular atrophy #SMA, or lung cancer in never smokers #LCINS? Check out our new study with David Beck @NYU, @kyliejwalters and @NadineSamaraLab now online at @embojournal doi.org/10.1038/s44318…
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Drake Williams retweetledi
Ever wonder how gut microbial food preferences influence host food preferences? Us too! Delighted to share work by Kristie Yu, @CelineSon11 & co on how gut bacterial metabolism of specific fibers influences host preference for diets containing those fibers biorxiv.org/content/10.110…
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Struggling to isolate single cells from mouse mucosa? Our study compares different enzyme-based dissociation methods and reveals how each technique impacts the recovery of specific cell types. Learn more about our findings here:
authors.elsevier.com/c/1iL4i52iy0reI
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Excited to share our new paper, Trem2 Promotes Foamy Macrophage Lipid Uptake and Survival in Atherosclerosis. Out today in Nature Cardiovascular Research! Great collaboration with @konsolerr @CFI_UMN @UMN_IBP @therealtyrone50
nature.com/articles/s4416…
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Happy to contribute to this by developing a pipeline for imaging and analysis of whole placenta and feto-placental arterial casts using μCT. Congratulations @geoffpronovost @pipethero @helenvuongphd et al!
@ScienceAdvances 📰👉doi.org/10.1126/sciadv…
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New preprint identifying shared and distinct mechanisms of inactivation of the #ubiquitin E1 enzyme #UBA1 across different diseases #VEXAS #SMA #lungcancer doi.org/10.1101/2023.1…
Thanks to David Beck @nyulangone, @kyliejwalters and all contributors for a great collaboration!
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@JMcLean_UW @UW_Kris @sbamashmous @gkotsakis_Perio Congratulations to all! A ton of interesting data to sift through
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Led by @UW_Kris, our team @sbamashmous @gkotsakis_Perio show that as inflammation in specific tissues around teeth is induced from #microbiome shifts, low-level changes in host cytokines and microbiome composition can also be detected in distant healthy sites despite brushing.
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Wonder what happens when you stop brushing? #gingivitis What about the impact of #inflammation on distant healthy oral tissue sites? Now in PNAS @PNASNews. @UW_Kris jsmcleanlab.com #microbiome #periodontal @UWDentalSchool pnas.org/doi/full/10.10…
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Drake Williams retweetledi
Increased STAT3 Activation in Periodontitis Drives Inflammatory Bone Loss - journals.sagepub.com/doi/abs/10.117…
Our small contribution to the understanding of STAT3 signaling in #periodontitis
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Huge congrats to @AshleyMToney for receiving a T32 award! We’re grateful to @RaedDweikMD and other members of the T32 executive committee. Check out Ashley’s interview 👀 lerner.ccf.org/news/article/?…
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Check out our work @NatureComms! A result of an enjoyable and fruitful multidisciplinary @NIDCR collaboration with the Werner lab @werner_achim revealing how a @ubiquitin based post- translational mechanism orchestrates early cranial ectodermal patterning. 🐣#devbio #NeuralCrest
Achim Werner@werner_achim
When #ubiquitin meets🐣 @NIDCR: check out our inspiring collaboration with @kerosuoLab, revealing how early brain, craniofacial and skin development are coordinated by a monoubiquitylation-based switch. Now out @NatureComms at rdcu.be/dhN90 Thank you to the team!
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