Dyno Therapeutics, Inc.

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Dyno Therapeutics, Inc.

Dyno Therapeutics, Inc.

@Dyno_Tx

Dyno Therapeutics is a pioneer in applying artificial intelligence to gene therapy, focused on AAV capsid engineering. Join our startup: https://t.co/Qw1SEcTjpp

Cambridge, MA Katılım Nisan 2018
56 Takip Edilen3.1K Takipçiler
Dyno Therapeutics, Inc.
Since 2019, 57 leading scientists and engineers have taken Dyno's machine learning interview challenge, a synthetic RNA design problem we use to evaluate expert candidates. Working with @Anthropic, we gave the same test to Claude Mythos Preview. It performed competitively with the best (ever) human experts. We wrote about what this means for the field. Read more on Substack: dynotx.substack.com/p/claude-mytho…
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Dyno Therapeutics, Inc.
We’re proud to announce that @AstellasUS has exercised its $15M option to license a Dyno AI-designed adeno-associated virus (AAV) capsid for skeletal muscle-targeted gene delivery, building on our 2021 collaboration agreement. This marks our second capsid license to a pharmaceutical partner, and it makes Dyno the first company to license AI-designed AAV capsids for both central nervous system (CNS) and muscle gene therapies. This milestone reflects years of platform development, validating our conviction that AI can solve the gene delivery challenge for therapeutic developers and ultimately create many good treatment options for patients. Learn more: businesswire.com/news/home/2026…
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Dyno Therapeutics, Inc.
#GeneticAgency is ultimately about individuals having options to live a healthier life – however they choose to define it for themselves. For those living with rare diseases, this first requires new treatment options. Hear sickle cell warrior Victoria Gray discuss her vision for this future with @ekelsic.
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Dyno Therapeutics, Inc.
Last month at @NVIDIAGTC, we released Dyno Psi-Phi, an agentic AI suite for protein binder with filters grounded in real experimental data to connect in silico workflows with real-world outcomes. We spoke with @xiaofei_lin at @GENbio about that challenge and the opportunities we see for AI agents to automate scientific discovery more broadly. Read the full piece: genengnews.com/topics/artific…
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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
Genetic agency – an individual’s ability to take action at the genetic level to live a healthier life – is a north star for the gene therapy ecosystem. The term emphasizes deeply personal decisions for patients and the scientific and technical challenges which will need to be overcome to deliver it. If you're inspired by what you hear below, check out more highlights from #GATC25@Dyno_Tx" target="_blank" rel="nofollow noopener">youtube.com/@Dyno_Tx
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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
What does it mean for genetic medicine developers to truly partner with patients? Victoria Gray, the first person to receive a CRISPR gene editing therapy for sickle cell disease and a speaker at the inaugural #GATC25, visited our office to sit down with CEO @ekelsic. They talked about genetic agency, the future of gene therapy, and why patients are essential partners in bridging the gap between scientific vision and real-world treatment options. Watch the conversation:
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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
At #GTC2026, @anthonycosta spoke about the leading edge of digital biology as a two-part story, defined by foundation models that encode what we know about biological systems at scale, and AI agents that accelerate our ability to experiment and iterate in real time. We’re proud of our ongoing collaboration with @NVIDIAHealth and to be part of a network of partners who are contributing to this story through the BioNeMo framework. Building on the La-Proteina family and integrating our core sequence design technology, we launched our Dyno Psi-Phi agentic AI suite for protein binder design. Great to see our work highlighted among so many of NVIDIA’s collaborators, who are also advancing therapeutic discovery for the patients who need it most.
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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
Today at #NVIDIAGTC, we announced the launch of Dyno Psi-Phi, a suite of AI-powered protein design tools developed in collaboration with @NVIDIA to help therapeutic developers create better medicines for patients everywhere. AI has made remarkable progress in generating protein sequences. But a persistent gap between computational predictions and real-world experimental outcomes has made it difficult to know which designs will actually work in the physical world, slowing the path from discovery to medicine. Dyno Psi-Phi is our answer to that challenge. The Psi-Phi suite pairs new generative models with state-of-the-art filters and accessible APIs, connecting in silico design to physical-world outcomes and putting frontier AI tools in the hands of developers across the field. Dyno Psi-1 is available through HuggingFace as an open-weight mode: huggingface.co/dynotx/dynopsi. Dyno Phi is available now at design.dynotx.com and through Claude Code. Press release: businesswire.com/news/home/2026… Blog post: dynotx.substack.com/p/dyno-psi-phi…
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"We need to change the conversation from 'there's no treatment' to 'there's no treatment yet.'" At the Genetic Agency Technology Conference (GATC), CEO @ekelsic introduced the idea of #GeneticAgency – an individual's ability to take action at the genetic level to live a healthier life – as a north star for the field of gene therapy. Watch Eric's opening remarks on what it will take to achieve this and why collaboration across the ecosystem is essential: youtube.com/watch?v=htHgt-…
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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
Advancing genetic medicines for rare disease patients takes a community. Hear from our CEO Eric on the collaboration behind #GATC25, and watch the highlights on our new YouTube channel: @Dyno_Tx/videos" target="_blank" rel="nofollow noopener">youtube.com/@Dyno_Tx/videos #RareDiseaseWeek #GeneticAgency
Eric Kelsic (he/him)@ekelsic

As #RareDiseaseWeek wraps up, I’m reflecting on how communities advance genetic medicines. Progress in rare disease therapeutic development doesn't happen in isolation. It takes researchers, technologists, physicians and patient advocates across the community working in concert to create the right treatment, show that it benefits patients, and make these medicines accessible. Today, most rare diseases patients have no available treatments that address the genetic cause of their disease. New technologies, including AI and gene therapy, are starting to change that, creating genetic agency for patients to help them live a healthier life. Last November, the inaugural Genetic Agency Technology Conference (GATC) brought 200 leaders across fields together in Boston to share their insights. This is what high-tech collaboration looks like, at scale. If you’d like to build technologies that empower patients with #GeneticAgency, we hope you join our GATC events this year. To catch more #GATC25 content or subscribe for updates, check out the new @Dyno_Tx YouTube Channel: @Dyno_Tx/videos" target="_blank" rel="nofollow noopener">youtube.com/@Dyno_Tx/videos

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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
We’re launching a Dyno YouTube channel to bring you closer to the science, technology, and people advancing #GeneticAgency. First up: exclusive content from our inaugural Genetic Agency Technology Conference (GATC), where we brought together therapeutic developers, technologists, AI pioneers and patient advocates to co-create the future of genetic medicine. Subscribe now → @Dyno_Tx" target="_blank" rel="nofollow noopener">youtube.com/@Dyno_Tx #GATC25
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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
We’re thrilled to be a Founding Host for Boston’s first-ever @techweek_, taking place May 26-31! If you’re building something in AI, biotech, deep tech, robotics, or beyond, now’s the time to get involved. Submit your event here: tech-week.com/host #BOSTechWeek
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Dyno Therapeutics, Inc.@Dyno_Tx·
At Dyno, we believe that progress in gene therapy depends on a strong ecosystem of partners to help developers confidently navigate the complex decisions behind every therapeutic breakthrough. On Substack, our Head of Partnership Success, Tyson Bertmaring, shares Dyno’s unconventional partnership success principles that guide how we work together and strengthen trust across the ecosystem, all in service of advancing genetic agency – an individual’s ability to take action at the genetic level to live a healthier life. Read more: open.substack.com/pub/dynotx/p/c…
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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
Congratulations to our partners at @NVIDIAHealth on expanding the BioNeMo platform, catalyzing the efforts of a community of AI developers working to revolutionize drug design! BioNeMo has been critical to our AI modeling and has truly advanced the field of AI drug discovery. Looking forward to seeing what comes next!
NVIDIA Healthcare@NVIDIAHealth

🌍 Revolutionizing Drug Discovery with AI + NVIDIA BioNeMo 🆕 The expansion announced at #JPM26 includes: - New open models like RNAPro (RNA structure prediction) & ReaSyn v2 (AI-driven synthesis design) - Powerful tools like BioNeMo Recipes & nvMolKit to scale model training and molecular discovery - Seamless integration of agentic and physical AI to accelerate science 📦 Unpack the details nvda.ws/45PyuwN

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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
▪️Readily manufactured by our partners at Trisk Bio and available today through the Dyno Frontiers Program
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Dyno Therapeutics, Inc.
Dyno Therapeutics, Inc.@Dyno_Tx·
We’re kicking off #JPM2026 with big news. Today we announced the launch of Dyno-yp2, a top-performing engineered capsid for CNS delivery.
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