Frederick Mann, PhD

Our new NAFA protocol robustly preserves delicate wounded tissues while facilitating probe/antibody penetration into internal tissues The fixation protocol is compatible for WISH on regenerating teleost fins, highlighting its versatility @ScienceStowers @BMCBiology #Fig8" target="_blank" rel="nofollow noopener">bmcbiol.biomedcentral.com/articles/10.11…

The @MBLScience Embryology Course is underway! 🔬🌊 Institute researchers from the @Planarial Lab, @Vidyanandsasi and @DungVuu are teaching assistants at #Embryo24. There is no better place to spend the summer than our satellite lab in #WoodsHole. #marinebiology #science

We just posted a new version of our planarian spatial transcriptomics story! Lots of new analysis & RNAi functional testing. Check it out! ⁦@ScienceStowers⁩ @fg_mann⁩⁩ ⁦@DungVuu⁩ ⁦@S_Nowotarski⁩ ⁦@Planaria1⁩ biorxiv.org/content/10.110…

Many many congratulations Dr @VirajDoddihal.. your beginners luck for that use of sword epic cOool 😍🤩 happy happy times Dr. Enjoys enjoys the glory of all ur hard work 🍾🥂😃🤩

Excited to announce the planarian transgenic workshop at Stowers, Nov. 7-10, organized by @Planaria1 and us, fully funded by NSF EDGE. Come to transfect worms and build your own luminescence microscope to monitor gene expression. Register at stowers.service-now.com/visitor?id=ext…. Please RT.

How does a small fragment of planarian regenerate an appropriately proportioned complete animal? As part of my PhD project I attempted to address this question with @Planaria1 @fg_mann , Eric Ross, & Sean McKinney @ScienceStowers @HHMINEWS Preprint: tinyurl.com/2hvb9j4z

What a year it has been @ScienceStowers !! This year as a post baccalaureate research scholar @GSSIMR has been nothing but amazing to me. I’ve learned SO much and I can only thank the @Planaria1 lab, @fg_mann for being the greatest mentor I could ever ask for.. 1/2

Today we celebrate Enya @DewarsEnya who a year ago joined our institute @ScienceStowers & our lab as a postbaccalaureate Enya will pursue her PhD @DukeU this fall While we will miss her, we wish her a world of new knowledge & discovery will always come to greet her Go science!

Dr. Biff Mann (@fg_mann) from @Planaria1 lab will discuss a genome-wide Smed RNAi library, and Pallob Barai from @BethMDuncan lab will speak about an RNase H-based ribodepletion strategy for transcriptomic profiling. We look forward to seeing you there! 2/2

@BlairBenhamPyle @DewarsEnya @S_Nowotarski @cindy_maddera @BrianSlaughter4 @Planaria1 Two more important contributions to recognize for our Slide-seq preprint: the expertise of Seth Malloy @burntmyfingys11 and Kate Hall, who were essential parts of getting this project done! We are very lucky to have been able to collaborate with them @ScienceStowers .

@BlairBenhamPyle and I co-led this work with a lot of help from Carolyn Brewster, @DewarsEnya, @S_Nowotarski, Carlos Guerrero-Hernandez, @cindy_maddera, Shiyuan Chen, Jason Morrison, @BrianSlaughter4, Anoja Perera, and @planaria1.

Check out our new preprints: we did Spatial Transcriptomics on regenerating planarians! Stem cells partner with matrix remodeling cells during regeneration biorxiv.org/content/10.110…

All of us will be presenting this work at this Friday’s #FlatwormFriday! So tune in!

Relatedly, our Slide-seq work was only possible because the incredible Carolyn Brewster created Syrah, a computational pipeline augmentation for Slide-seqV2. @BlairBenhamPyle, @planaria1, and I have been so lucky to be a part of this. biorxiv.org/content/10.110…

It was a great experience writing a chapter on diverse types of #regeneration with @Planaria1 @ScienceStowers . Can’t wait to get my hands on this book to read all the other exciting chapters.Thanks for the opportunity @CSHLPress @Ken_Poss_Lab @FoxLabDuke. Loved the cover page!

Congratulations to @planaria1 for his election to #AAASFellow by @AAAS. Fellows are selected for their achievements & extraordinary efforts on behalf of the advancement of science. Read more about the awardees here: aaas.org/news/aaas-hono…

Sonpho et al. provide an experimental approach for identifying both known and novel ECM components involved in regeneration — @Planaria1 @ScienceStowers @MahidolU #ECM #TeamMassSpec mcponline.org/article/S1535-…

Have a look at our new paper, which reports unexpected roles for Hox genes in adult planarians! This beautiful surprising project was led by @cparnoldphd and we are all so happy to share it.

From the laboratory of @Planaria1 @ScienceStowers, our paper identifying unsuspected roles for Hox genes in adult tissues is now out in @NatureComms. Here is a summary thread of the story. @HHMINEWS @NIGMS. #hoxgenes #invertebrates 1/16 nature.com/articles/s4146…

Sharing the latest preprint from @Planaria1 lab describing a protocol for WISH and immunostaining while preserving delicate tissues. Carlos is the superstar behind this protocol and was such a fun collaboration with @fg_mann @ScienceStowers @GSSIMR tinyurl.com/7xwssp3n