
Renuka Figueiredo
311 posts

Renuka Figueiredo
@figueiratively
on hiatus Prev : ops Ninja @LoopHealthHQ (YC W20)advocacy (https://t.co/9vF0Ec2hzR), science (https://t.co/rcbYhZc6s5) and impact (https://t.co/g60mjckvvW)




Trikafta is one of the most inspiring medical advances in decades. Approved in 2019, the drug at first makes cystic fibrosis patients vomit up mucus for a whole day. But while they lose that day, they gain a lifetime–a healthy, *normal length* lifetime. It's a miracle drug.








This report is long but very good. “With R1, DeepSeek essentially cracked one of the holy grails of AI: getting models to reason step-by-step without relying on massive supervised datasets. Their DeepSeek-R1-Zero experiment showed something remarkable: using pure reinforcement learning with carefully crafted reward functions, they managed to get models to develop sophisticated reasoning capabilities completely autonomously. This wasn't just about solving problems— the model organically learned to generate long chains of thought, self-verify its work, and allocate more computation time to harder problems. The technical breakthrough here was their novel approach to reward modeling. Rather than using complex neural reward models that can lead to "reward hacking" (where the model finds bogus ways to boost their rewards that don't actually lead to better real-world model performance), they developed a clever rule-based system that combines accuracy rewards (verifying final answers) with format rewards (encouraging structured thinking). This simpler approach turned out to be more robust and scalable than the process-based reward models that others have tried.” shorturl.at/TTHqT



Moo Deng the most beautiful girl in the world


Quite a Study: "4 of 5 living organs donors in India are women. 4 of 5 recipients men"








