Cheen Euong Ang

259 posts

Cheen Euong Ang

Cheen Euong Ang

@hhhcce

Stem cell and RNA biologist. Spatial Imaging Enthusiast. McGill. Stanford BioE. Postdoc Harvard CCB. Simons BTI Fellow. PI at Mount Sinai. https://t.co/2bJsxcfgCG

Katılım Ocak 2009
1.3K Takip Edilen229 Takipçiler
Katie Galloway
Katie Galloway@GallowayLabMIT·
Could the folding of synthetic gene circuits in 3D shape how genes are expressed? Today @ScienceMagazine we report on the role of gene syntax in shaping feedback between transcriptional activity and genome folding for advanced circuit design🧵 (1/n)
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Katie Galloway
Katie Galloway@GallowayLabMIT·
Wild to see this in print for the first time
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Jiefu Li
Jiefu Li@JiefuBiol·
Luminal surface proteome of the brain vasculature uncovers blood-brain barrier regulators @ScienceMagazine: science.org/doi/10.1126/sc… Big thanks to Zijian, Zuzhi, Yupu, Khanh, Yuxiang, and all collaborators to make this possible!
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Ruobo Zhou
Ruobo Zhou@RuoboZhou·
🚨 New paper out in JACS Au! We introduce CLaSSiNET, a computational framework to reconstruct and classify cytoskeletal networks from sparse SMLM data—revealing new organization rules of the actin–spectrin membrane skeleton and its coupling to actin fibers.pubs.acs.org/doi/10.1021/ja…
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Lingyan Shi
Lingyan Shi@StimulatedRaman·
I am incredibly proud to share that my postdoc Yajuan has accepted a position as Tenure-Track Assistant Professor at Yale University. Please join me in congratulating her on this achievement! Many thanks to our colleagues, collaborators, friends, and group members.
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Sai Ma
Sai Ma@saima_lab·
1/ Exciting news! We just released a preprint on a new single-cell technology, ME-seq, that maps DNA methylation, gene expression & chromatin accessibility—all in the same cell, at scale. And yes, it’s a LOT cheaper 🤑than current methods! 🧬 #SingleCell #Epigenetics
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Xiaoyu Chen
Xiaoyu Chen@XiaoyuChenxy·
I am thrilled to share that I will be starting my lab in the Center for Pediatric Neurological Disease Research (CPNDR) at St. Jude Children’s Research Hospital as a faculty member @StJude @StJudeResearch. Deeply grateful for the incredible mentorship, support and camaraderie in the @Sergiu_P_Pasca lab. In this next chapter at St. Jude, the Chen lab is hiring postdoctoral research associates and welcomes visiting students and scholars to join us!!! Our lab aims to accelerate therapeutic development for brain disorders, leveraging human (stem cell)-derived models and gene targeting tools. Research themes: - How do genetic variants contribute to pediatric neurological disease at the molecular, cellular, circuit and organismal levels? - How can we push the boundaries of human-derived models to tackle disease (e.g., benchmarking 3D culture and high throughput drug discovery)? Interested? Reach out for collaborations or apply for postdoc positions 👇: talent.stjude.org/careers/jobs/J… Postdoc Benefits (including a 7% 403b match): stjude.org/education-trai… #postdoc #organoids #Neuroscience
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Xuebing Wu
Xuebing Wu@wu_xuebing·
Does the noncoding genome actually carry more genetic information than coding seqs? Motivated by this question we mutated every bp in the 10kb MYC locus. Results are even more exciting: Decoding the MYC locus reveals a druggable ultraconserved RNA element biorxiv.org/content/10.648…
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Xiaoyu Shi
Xiaoyu Shi@XiaoyuShi2·
Thrilled to see our work on land-ExM 🏜️published in @JCellBiol! It is a high signal, super-res approach that maps protein and lipid ultrastructure simultaneously, allowing us to see 3D interactions of organelles and phase separations like never before. 🔬#ExM #CellBiology
Journal of Cell Biology@JCellBiol

.@YinyinZhuang, @XiaoyuShi2 et al. @UCIrvine introduce land-ExM, a superresolution approach that simultaneously maps protein and #lipid ultrastructure to reveal 3D interactions of #membrane #organelles and condensates. hubs.la/Q040wj510 #ExM #Microscopy #StructuralBiology

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Cheen Euong Ang retweetledi
Dieter Egli
Dieter Egli@EgliDieter·
Sad to hear about the passing of David Baltimore. We lost a giant who was here from the early days of the molecular biology revolution. From the Asilomar conference on recombinant DNA to heritable gene editing, he remained an important voice. I never met him, but his impact will continue. nytimes.com/2025/09/07/sci…
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Junyue
Junyue@junyue_cao·
Our spatiotemporal atlas of brain aging under caloric restriction is out: sciencedirect.com/science/articl…. Thanks to all authors, reviewers, and the great support from @RockefellerUniv, Brain Research Foundation (@TheBRF), and the Center for Integrated Cellular Analysis (@cegs_ica)!
Junyue@junyue_cao

Excited to share our first anti-aging intervention study, led by brilliant Zehao @Tommyz626, Alex @alexepstein_bio, and Chloe @chloe__schaefer from our lab at @RockefellerUniv! With a cost-effective spatiotemporal analysis pipeline, we identified the aging-associated cell population dynamics that can be specifically rescued by caloric restriction in the mammalian brain!

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Evgeny Kvon
Evgeny Kvon@evgenykvon·
Our preprint describing the Range Extender element, which is required and sufficient for long-range enhancer activation at the Shh locus, is out in @Nature. nature.com/articles/s4158…
Evgeny Kvon tweet media
Evgeny Kvon@evgenykvon

How do enhancers work over distances that sometimes exceed megabases? Excited to share our work led by @gracecbower where we uncover a unique sequence signature globally associated with long-range enhancer-promoter interactions in developing limb buds: biorxiv.org/content/10.110… 1/

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Sri Kosuri
Sri Kosuri@srikosuri·
Good news. After 2 rounds of venetoclax, GO, + chemo, my daughter has had a complete response. No detectable signs of the tumor that had completely shut her eye, which she was dangerously close to losing. 🙏🏾 to the amazing team @StJude & the community for helping us get here.
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Xuyu Qian
Xuyu Qian@QianXuyu·
I'm thrilled to share that I will be starting my independent lab this winter as a tenure-track Assistant Professor at the new BRIDGE Center at @ChildrensPhila and @PennMedicine! Grateful for the support from mentors, collaborators, and friends—excited for what's ahead! 🧠✨
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