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BREAKTHROUGH: Colossal scientists hatched healthy chicks from artificial eggs. No shells. No hens. Just bioengineered eggs that breathe like the real thing. This could help bring back giant extinct birds like the South Island giant moa, whose eggs were ~80x a chicken’s. (1/10)

Yann LeCun says LLMs are strongest in domains where language itself is the substrate of reasoning, like math and code They can solve problems, prove theorems, and write programs — but they are not creative mathematicians, software architects, or computer scientists "their role is to help humans build"

Humanoid skills are about to make Claude Skills look like a joke Unitree just launched UNISTORE, an app store for humanoid robots. You can create, publish, buy, and deploy robot skills with one click across all their models. Just the motion library is live right now: basic moves, dances, martial arts, all available as free downloads. It's only out in China now (international coming soon). But the platform move is obvious: Unitree is building the iOS of physical robots. Now imagine what this looks like once it matures: Right now when you download a skill for Claude or Codex, it changes how your AI writes and works inside your computer. It's all just digital output, stuff that happens on a screen. But when you download a skill for a robot, it changes what a physical machine can do in your house, your warehouse, your office. One click and suddenly your robot knows how to make coffee. Another and it's running nightly inventory in a warehouse, sorting and logging without supervision. Another and it's harvesting ripe produce row by row from your garden, adjusting grip pressure for each fruit so nothing gets bruised. We're going from downloading apps for phones to downloading skills for AI to downloading physical capabilities for robots that operate in the real world. Very cool to think about. I made a visual of what this might look like in the future:

This is the automotive world’s BlackBerry to iPhone moment.

It now costs a millennial $252 on average for a date, per BMO.

carved by logic. Topology optimization is just madness

🚨 I HAVE NO MICROPLASTICS IN MY BALLS 🚨 This should not be possible. Studies show that 100% of men have microplastics in their semen. I am the first human ever to show a complete reduction to zero. This may be a world-first breakthrough in fertility research. I had 165 microplastic particles in my semen just 18 months ago. Now, I have zero. Five published studies have measured microplastics in human semen. Two found them in 100% of men. The other three found then in 44 to 76% of men tested, but those used methods that miss the smallest particles and the clear ones. Corrected for that, the real rate is likely 100%. Almost every man alive has plastic in his semen right now. The same applies to testicular tissue, testing 100% positive for microplastics. Microplastics hurt sperm. Human studies show the impact of various types of plastic, associated chemicals, and other toxins on male fertility: + 60% fewer normal shaped sperm (from PFAS) + 5x higher odds of low sperm count (from PTFE) + 10% lower sperm concentration (from PTFE) + 15% lower swimming ability (from PTFE) + 41% lower swimming ability (from PET) + 12% lower sperm swimming ability (from BPA) + 3x higher odds of low sperm count (from Phthalates) + 2x higher odds of poor swimming (from Phthalates) The effects compound: each extra type of plastic drops sperm swimming ability by about 21%. This matters even if you’re NOT trying to get pregnant. Sperm count is one of the cleanest biomarkers of overall health we have. And microplastics don't stop at the testes. The same particles are showing up everywhere we look. Studies show 4.5x higher rate of heart attack, stroke, and death in people with microplastics in their arterial plaque vs. those without. Microplastics were also found in 100% of human placentas tested. 100% of post-mortem human brains tested positive for microplastics. Brain concentrations rose ~50% between 2016 and 2024, and now sit at roughly 11x the levels found in the liver or kidney. Where do these come from? + PTFE, commonly in non-stick pans + PET, water bottles + Phthalates, makes plastic soft and bendy + BPA, can linings + PFAS, stain-resistant fabrics & food packaging Inside the body, plastic causes a kind of cellular rust. It triggers inflammation in the testicles, kills the cells that make sperm and drops testosterone. It's been confirmed across 39 animal and cell studies, then in human data. MY PROTOCOL: Note, what I did is n=1, not a controlled trial, I cannot prove cause. 1. Sauna (dry). My toxin blood panel confirms sauna clears plastic related chemicals: BPA, phthalates, PFAS, flame retardants, pesticides. The plastic particles themselves are too big to sweat out directly. Heat may activate other clearance routes: bile flow through the liver, the cell's internal cleanup system, and the gut barrier. Humans have almost no enzymes that can break plastic apart, so the body has to physically push it out. 2. Reverse osmosis water filter. Drinking water is likely a major source of microplastic getting into your body. A reverse osmosis filter pushes water through a very tight membrane and strains the particles out. I filter everything I drink. 3. Trying to rid my environment of the big plastic items: cutting boards, cups, plates, food storage containers, non-stick pans, cling wrap, tea bags, water bottles, kitchen utensils, kettles, and synthetic clothing. Note, as hard as I try, I'm always finding new plastic things in my life. This can be all-consuming thing so try to just knock out the big ones. I did all three interventions at the same time. I cannot say which one did the most work. What I can say is this: going from 165 to zero in 18 months is possible. Results: Nov 2024: 165 particles/mL Jul 2025: 20 particles/mL Apr 2026: 0 particles/mL The 18 month window also captures roughly 7 full spermatogenesis cycles.

Claude for Excel, PowerPoint, and Word are now generally available, and Claude for Outlook is in public beta. As Claude moves between your Microsoft apps, it carries the full context of your conversation.

A new study just blew up the entire "vibe coding" movement. Researchers from UC San Diego and Cornell tracked 112 experienced software developers using AI agents in their actual jobs. The finding is the opposite of every viral demo on your timeline. Professional developers don't vibe code. They control. Here's what they actually found. The researchers ran two studies. 13 developers were observed live as they coded with agents in real production work. 99 more answered a deep qualitative survey. Every participant had at least 3 years of professional experience. Some had 25. The viral pitch of agentic coding goes like this. Hand the agent a vague prompt. Don't read the diff. Forget the code even exists. Trust the vibes. Andrej Karpathy coined the term. Tens of thousands of developers on X claim to run "dozens of agents at once" building entire production systems hands-off. The data says almost nobody serious actually works that way. Here is what experienced developers do instead. → They plan before they prompt. They write out the architecture, the constraints, and the edge cases first, then hand the agent a tightly scoped task. → They review every diff. Not because they're paranoid. Because they've seen what happens when you don't. → They constrain the agent's blast radius. Small, well-defined tasks only. The moment a problem touches multiple systems or has unclear requirements, they take over. → They treat the agent like a fast junior dev that needs supervision, not a senior engineer that can be trusted alone. The researchers also found something darker buried in the data. A separate randomized trial they cite showed that experienced open source maintainers were 19% slower when allowed to use AI. A different agentic system deployed in a real issue tracker had only 8% of its invocations result in a merged pull request. 92% failure rate in production. 19% productivity drop for senior devs. The viral demos lied to you. The paper's biggest insight is in one sentence: experienced developers feel positive about AI agents only when they remain in control. The moment they let go, quality collapses, and they know it. This matches what every serious shop has quietly figured out. The developers shipping the most with AI right now aren't the ones vibing. They're the ones with the strictest review processes, the tightest task scoping, and the clearest mental model of what the agent can and cannot do. Vibe coding makes for great Twitter videos. It does not make great software. The next time someone tells you they let Claude build their entire SaaS in a weekend, ask them how much of that code they've actually read. The honest answer separates real engineers from the demo crowd.