Ivo Veletic, MD

Our #Opal bone marrow image is featured on the new @BloodPortfolio cover, highlighting the discovery of OSMR as a novel #AML biomarker. This work was led by @HusseinAbbasLab, @patrickreville, @BofeiWang3 and @JenMarvinPeek at @MDAndersonNews. Learn more: bit.ly/4d5MdC5

Pleased to share our new study led by @HusseinAbbasLab, just published in @Nature_NPJ Precision Oncology! We reveal the presence of tertiary lymphoid-like structures (TLS) in the bone marrow of #AML patients using high-plex #SpatialProteomics. Learn more: nature.com/articles/s4169…

Excited to share our new paper out today in @LeukemiaJnl! CLL cell-derived #exosomes disrupt immune and hematopoietic systems – reprogramming immune cells, suppressing hematopoiesis, and driving disease. Read full article: rdcu.be/eglXM @MDAndersonNews #CLL #leusm

Great poster session on the temporal dynamics of bone marrow fibrocytes in primary #myelofibrosis at #ASH24 #MPNSM! Enjoyed the insightful discussions with @doctorpemm @MDAndersonNews. Learn more: ash.confex.com/ash/2024/webpr…

A second paper out on the same day! Also happy to share our @J_Immunol study in #CLL cells. This work shows how constitutively activated #STAT3 induces the expression of #PTX3, a key promotor of #fibrocyte differentiation. Link 👇 jimmunol.org/content/early/… @MDAndersonNews #leusm

Proud to share our latest work on #myelofibrosis #fibrocytes and the role #GLI1 plays in survival and dysfunction of these monocyte-derived cells. Could targeting STAT3-GLI1 axis alleviate BM fibrosis in MF? Full paper: rdcu.be/cN0p6 @cddpress @MDAndersonNews #MPNSM

#ASH19: STAT3-induced Gli1 promotes #fibrocyte differentiation in MF. Join us at poster booth # 2961 Abstract: bit.ly/351Chpn @LeukemiaMDA #MPN

We are competing for the Blood cover of the year! Vote for our cover here: a.cstmapp.com/voteme/881939/… @LeukemiaMDA @MDAndersonNews #ASH19 #MPN

Our new paper just out: Neoplastic #monocytes induce #myelofibrosis-like phenotype in immunodeficient mice and give rise to #megakaryocyte progenitor cells | #mpnsm @PLOSONE @LeukemiaMDA dx.plos.org/10.1371/journa…

On this cover JAK2 is phosphorylated in tartrate-resistant acid phosphatase/cathepsin K –positive osteoclasts located along sclerotic bone trabecula of a myelofibrosis patient with a JAK2V617F mutation. bloodjournal.org/content/133/21…

Cover article: Myelofibrosis osteoclasts are clonal and functionally impaired bloodjournal.org/content/133/21…

Our team's work on clonal and dysfunctional #osteoclasts in #myelofibrosis is featured on the cover of the new issue of @BloodJournal | bit.ly/2YIe0Bh | #mpnsm @LeukemiaMDA @MDAndersonNews

#ASH18 MPN oral clinical | Dr Srdan Verstovsek @LeukemiaMDA presenting our group's first results with pentraxin analogue PRM-151 in #myelofibrosis pts, incl. promising reduction in BM #fibrocyte counts and #fibrosis levels | bit.ly/2KOYEFb #MPNsm

Check out our #ASH18 poster on the role of #Gli1+ BM #fibrocytes in #myelofibrosis (Abstract 1793: bit.ly/2BLVak8) #MPN @LeukemiaMDA

Couple of treatment key points from @LeukemiaMDA meeting currently taking place in #Croatia

This year's #NobelPrize goes to Dr. Allison at our institution for the discovery of new generation of #immunotherapy @LeukemiaMDA @MDAndersonNews

#MPNSM = Myeloproliferative Neoplasms on Social Media | follow the discussions in field of MPN on Twitter at #MPNSM | @AaronGerds @mtmdphd @Vikas_Gupta_1 @mpdrc @jjkiladjian @andrewschorr @PatientPower @VJHemOnc @MPN_RF @mpnadvocacy @LeukemiaMDA @lauracmichaelis @BldCancerDoc

Our group's latest report underlines the relevance of targeting neoplastic #monocytes in #myelofibrosis @LeukemiaMDA #mpn onlinelibrary.wiley.com/doi/full/10.11…