Jason Buenrostro

646 posts

Jason Buenrostro

Jason Buenrostro

@JD_Buenrostro

Katılım Ağustos 2016
682 Takip Edilen5.7K Takipçiler
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Jason Buenrostro
Jason Buenrostro@JD_Buenrostro·
I’m so honored and grateful to be named a MacArthur Fellow! I’ve been absolutely flooded with texts, emails and likes. What a wonderful experience to hear from colleagues, collaborators, friends, and family. Thank you all for the support and encouragement! twitter.com/macfound/statu…
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Anders Sejr Hansen
Anders Sejr Hansen@Anders_S_Hansen·
(1/n) Super excited to share that our preprint is out today in @NatureSMB with a new name "Integrated MINFLUX tracking reveals two distinct chromatin dynamics classes across cell types" and more than 2x more data: nature.com/articles/s4159… MIT NEWS: news.mit.edu/2026/how-chrom…
Anders Sejr Hansen tweet mediaAnders Sejr Hansen tweet media
Anders Sejr Hansen@Anders_S_Hansen

(1/13) Thread on @mazzocca_matteo @DomenicNarducci @SGrosseHolz @_jessematthias new preprint Q: how does chromatin move? Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide some answers biorxiv.org/content/10.110…

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Gene Regulation Observatory
Gene Regulation Observatory@GRO_Broad·
Check out the latest from @Rachel_E_Savage, @JD_Buenrostro and many collaborators as part of the @IGVFConsortium
Rachel Savage@Rachel_E_Savage

It takes two (transcription factors) to tango Transcription factor collaboration enables precise T cell state engineering tinyurl.com/tcelltfs Excited to share our preprint with @JD_Buenrostro, @cgersbach, and an incredible team of collaborators as part of @IGVFConsortium 🧵

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Jason Buenrostro
Jason Buenrostro@JD_Buenrostro·
@CalebLareau is doing some of the most compelling work on viral contributions to human disease. Here showing herpesvirus reactivation in Alzheimer’s disease. x.com/CalebLareau/st…
Caleb Lareau@CalebLareau

A history of viral encephalitis is one of the strongest risk factors for developing dementia. With @JacobJacobog02, Yifan Chen, @RNA_Life, and @RyanDhindsa, we refine this link by describing a neuronal cell type that can reactivate HSV-1 in humans 1/n biorxiv.org/content/10.648…

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Sam Peng
Sam Peng@CTSPeng·
Excited to share our work on ErbB receptors published today @CellCellPress! Using multicolor, photostable UCNPs, we perform long-term (>15 min) single-particle tracking of EGFR, HER2, and HER3, enabling direct visualization of dimerization in live cells. cell.com/cell/fulltext/…
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Avi Roy
Avi Roy@agingroy·
A weekly jab in the belly is generating more revenue than the entire AI industry. Ozempic + Mounjaro: $71B in 2025. OpenAI + Anthropic: $29B. And they've barely started. ~2% of the 800 million eligible patients can currently access them. h/t @DrSamuelBHume
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Indranil Singh
Indranil Singh@cancer_curious·
So I bought from Addgene , what I once submitted to Addgene 😅
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IGVF
IGVF@IGVFConsortium·
Transcription factor collaboration is key to shaping T cell states; this preprint maps it at scale. Dive into the full thread for how the research came together. 👇
Rachel Savage@Rachel_E_Savage

It takes two (transcription factors) to tango Transcription factor collaboration enables precise T cell state engineering tinyurl.com/tcelltfs Excited to share our preprint with @JD_Buenrostro, @cgersbach, and an incredible team of collaborators as part of @IGVFConsortium 🧵

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Jason Buenrostro
Jason Buenrostro@JD_Buenrostro·
@HSCRB I’ll again thank @cgersbach, @Rachel_E_Savage and team. Please reach out with feedback. Also check out Rachel’s great thread on the paper: x.com/Rachel_E_Savag…
Rachel Savage@Rachel_E_Savage

It takes two (transcription factors) to tango Transcription factor collaboration enables precise T cell state engineering tinyurl.com/tcelltfs Excited to share our preprint with @JD_Buenrostro, @cgersbach, and an incredible team of collaborators as part of @IGVFConsortium 🧵

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Jason Buenrostro
Jason Buenrostro@JD_Buenrostro·
We then engineered this interaction: we synthetically tethered RUNX2 and KLF2, forcing their collaboration to create a stronger and more specific gene expression response. We’re excited about this direction. Synthetic TF tethering may provide a general approach for engineering gene expression in cells, and a path toward more programmable control of cell identity.
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Rachel Savage
Rachel Savage@Rachel_E_Savage·
It takes two (transcription factors) to tango Transcription factor collaboration enables precise T cell state engineering tinyurl.com/tcelltfs Excited to share our preprint with @JD_Buenrostro, @cgersbach, and an incredible team of collaborators as part of @IGVFConsortium 🧵
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Eric Topol
Eric Topol@EricTopol·
Why are we seeing so much early-onset colorectal cancer? The correlation with pesticide exposure and its epigenetic signature, adjusted for all known risk factors. (doesn't establish cause and effect) nature.com/articles/s4159…
Eric Topol tweet mediaEric Topol tweet media
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Itai Yanai
Itai Yanai@ItaiYanai·
How does a cell learn? In our new perspective in @Nature we propose a model where the properties of the AP-1 family of transcription factors – stress-induced feedback, regulatory combinatorics & cellular memory – encode a mechanism for cellular learning. nature.com/articles/s4158…
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Yash Pershad
Yash Pershad@yash_pershad·
New preprint out! We asked: can we tell which CHIP mutations actually matter for disease risk? Analyzing >1 million individuals across @ukbiobank, @AllofUsResearch, and @VUMChealth BioVU — here's what we found. 🧵 (1/9)
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Keşfet

@sara_mostafavi @biorxivpreprint @Rachel_E_Savage @NatureSMB @IGVFConsortium @CalebLareau @CellCellPress @DrSamuelBHume