José Filippini
159 posts
Basically almost everyone running peptides for fat loss is doing it wrong.
It took me a month, but I put together the most comprehensive FREE fat-loss peptide guide on the internet:
40 peptides, 10 chapters, 20 stacks, and more.
Just comment "BIBLE" and I'll send it to you.
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1 in 10 Americans now has an autoimmune disease.
Lupus.
Crohn's.
Hashimoto's.
Type 1 diabetes.
Multiple sclerosis.
Rheumatoid arthritis.
Your doctor will tell you it's genetic.
Or bad luck.
Or that your immune system just "turned on itself."
Harvard researchers disagree.
A pediatric gastroenterologist at Mass General (Dr. Alessio Fasano) spent 20 years tracking down the missing piece.
What he found changed the conversation.
Every autoimmune disease he studied shared the same three ingredients:
- A specific environmental trigger
- Genetic predisposition
- A leaky gut
Take any one of those away, and the disease doesn't start.
The gut isn't just where food gets digested.
It's a one-cell-thick wall -
The only thing standing between your bloodstream and everything you eat, drink, and swallow.
When that wall is tight, your immune system stays calm.
When it's leaky,
Undigested food particles and bacterial fragments slip through into your blood.
Your immune system sees invaders and attacks.
But the particles look a lot like your own tissue.
Attack the gluten fragments → attack the thyroid (Hashimoto's)
Attack the bacterial fragments → attack the joints (rheumatoid arthritis)
Attack them over and over → attack the nerves (MS), the gut (Crohn's), the pancreas (Type 1)
This is called molecular mimicry.
Here's what people report when they heal the gut wall:
Skin clearing up
Brain fog clearing up
Digestion finally working
Joint pain fading within weeks
Autoimmune flares slowing down
Energy returning after years of fatigue
The things that punch holes in the gut wall:
Gluten (yes, even if you don't have celiac)
Glyphosate on conventional crops
NSAIDs (ibuprofen, aspirin)
Ultra-processed food
Chronic stress
Antibiotics
Poor sleep
None of these are rare.
Most people have all seven running on autopilot.
I've been saying for 30 years: almost every chronic disease traces back to a broken gut.
The science keeps catching up.
The good news?
Unlike your genes, the gut wall is something you can actually rebuild.
Comment RESTORE and I'll send you a free guide on how to heal the gut and calm the immune system naturally.
P.S. MUST Follow for me to DM you.
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Stanford scientists found one bacteria missing in almost every obese, diabetic, and inflamed patient they studied.
It's supposed to make up 3-5% of your gut.
In people with metabolic problems, it's often 3,000 times lower.
This bacteria has one job.
It lives in the mucus lining of your gut wall,
The last layer of defense between your bloodstream and the outside world.
It eats old mucus, stimulates your body to make fresh mucus, and seals the wall tight.
When it's there, your gut barrier is strong.
When it's gone, the wall thins:
Weight becomes harder to lose
Food particles leak through
Blood sugar misbehaves
Cholesterol creeps up
Inflammation climbs
Researchers at Nature Medicine gave this bacteria to overweight adults for 3 months.
The results:
- Cholesterol dropped
- Insulin sensitivity improved
- Liver inflammation markers fell
- Gut barrier function strengthened
- Body weight started trending down without a single diet change
Here's what people are reporting when they rebuild this strain and its probiotic cousins:
Blood sugar stabilizing
Cravings for sugar fading
Bloating disappearing in days
Skin clearing after years of struggle
Clothes fitting differently in a matter of weeks
What destroys this bacteria?
Alcohol
Antibiotics
Chronic stress
Artificial sweeteners
High-fat, high-sugar processed diets
You can't buy this specific strain at most health food stores.
But you can feed the bacteria you already have, and colonize with related strains that do similar work -
At levels 10x higher than any capsule.
The trick is fermentation.
A jar of homemade yogurt fermented with the right strain for 36 hours at the right temperature can deliver 200+ billion live probiotic cultures per serving.
A store-bought yogurt?
Maybe 1 billion if you're lucky.
Dr. William Davis (author of "Super Gut") has spent years documenting exactly how to do this at home.
I've been making it myself for 3 years.
The difference in how I feel is night and day.
Comment PROBIOTICS and I'll send you the free guide on how to make unlimited probiotics at home.
P.S. MUST Follow for me to DM you.
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@iamfakhrealam im suprised that it is so good.
maybe the best research llm rn
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RIP McKinsey..
Kimi 2 just did in 2 mins what consultants charge $50k for.
Here’s my workflow + 5 insane experiments:
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Doesn't matter how much money you have.
Without health, you're broke.
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@EPBResearch @EPBResearch why the comparison with those years?
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The trend in continued jobless claims remains compared to 2022, 2019, and 2018.
Note the shift from Week 1-12, when claims were running below the baseline, to claims now holding above the baseline.
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Imagine a Christian getting to heaven's gate and realizing their God wasn't God, but instead Allah, or Krishna, or Zeus, or Thor. And then seeing sinners and heathens ascending the stairs to the holy gates too. That's Bitcoiners realizing that they bet on the wrong horse. That there wasn't anything particular moral or pure or sacred about Bitcoin, and that the world doesn’t actually care about how immaculate the conception really was.
In the second world, in which Bitcoin continued to thrive, but other coins did so as well, and perhaps surpassed it, the laser eyes would have to admit that they never had any special insight. That the revelations they had so keenly felt were shadows and illusions. That their gurus were false prophets. And this crisis of faith – inching closer every day thanks to simple material reality – is too painful to bear, so they pray and hope for the collapse of all of the sh*tcoins and the impure Bitcoin competitors and all of the distractions to the ordained mission.
So even though Binance and Coinbase did something immensely good for Bitcoin, and surely added tens or hundreds of billions to its market cap by virtue of the tools they built to support it, they didn’t do it in a pure way. They sinned by building technology for other coins. By allowing ETH and SOL and XRP to thrive alongside Bitcoin, too. They sinned by not following the holy virtue of Self Custody at all costs (notwithstanding of course that the market didn’t _want_ self custody). They sinned by not prioritizing the ordained Scaling Solution of Truth in the form of the Lightning Network but instead building other products (that their users wanted) first.
They sinned by (allegedly, in the diseased minds of maxis) creating “paper” Bitcoin out of thin air, thus wrongfully driving down the price of Bitcoin with dilution that wouldn’t otherwise exist. (This is a classic goldbug myth that the Bitcoiners inherited for some deranged reason). But most of all they sinned by being polytheists in a monotheist world. And for that, they deserve to be destroyed. Even if Binance operates the biggest p2p onramp to Bitcoin in the global south. (The laser eyes are unconcerned with data or empirical facts.) Even if Coinbase went to bat for Bitcoin versus US regulators for over a decade. Even if the two firms custody more Bitcoin for end users than anyone else. This doesn’t matter. They’re impure, and laser eye Bitcoiners aren’t here for the profit or the adoption. They’re here to feel morally superior, to dunk on sh*tcoiners, to accelerate towards the rapture in which all fiat dies. They aren’t trying to reform the existing system or accept half-measures like third party custody, even if highly credible. They aren’t here for distractions like DeFi or Web3. They’re here to act out an imagined monetary revolution, mainly on twitter.
This is why the laser eye reaction to the US government attacking stalwart firms like Coinbase or Binance is so revealing. The maxis don’t care about actual progress or key wins for the industry. They don’t care about the 100m+ individuals using these firms to hold their coins. They don’t care about adoption. They don’t even care about price appreciation (remember, their desire for in-group kinship far exceeds their economic motive). They care about being pure, adhering to the imagined codes of conduct set by their gurus. Even though they ostensibly disdain the usage of state power, they are more than happy to wield it against their enemies if it achieves the goals of the revolution. They care about treasuring the sacred and attacking the profane.
Like all secular cults, the Bitcoin maxi cult is borne out of a loss of meaning in modern society. These people are mostly outcasts who believe that society exists in a fallen state, only to be restored by a monetary revolution. Happy, functional people don’t spend their days weaving conspiracies about how Jay Powell is specifically conspiring against them. I’m sympathetic to their search for meaning, but unfortunately as with many secular cults, their programming has gone haywire. Like ducklings believing a human stranger is their mommy, the laser eyes have imprinted upon a technology and wrongly believe it will be their salvation. It’s nothing of the sort. It’s a tool, a very good one, but nothing more. It’s not a culture and it’s not a way of life.
Unfortunately, the maxi cult isn’t interested in adoption or the success and proliferation of Bitcoin, but merely its advance in a theologically acceptable manner. But their cult is exclusionary and trades off against the actual usage of Bitcoin as a way to promote financial liberation. For this reason, the maxi cult must be resisted at all costs. Bitcoin’s fat depends on it.
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If you're somewhat new to the space and you're wondering why self-professed Bitcoiners today cheered on SEC attacks against the two most important Bitcoin companies of all time, Coinbase and Binance, let me explain...
There's "people who use Bitcoin" aka Bitcoiners (the vast majority, ordinary people) and there's people that turned Bitcoin into a secular cult. Call this latter group "laser eyes" or "maxis", whatever you want, they know who they are, we know who they are. There's no uncertainty about this – they are people that elevated Bitcoin from a mere tool to a belief system, a way of life. (They like to quibble over the language but everyone knows who is who here.)
The vast majority of these cult adherents are actually new to Bitcoin. Look at their profiles – mostly created 2021 and 2022. They are latecomers, drawn in by the rally in 2021 and the promise of riches and endless price appreciation spun by gurus on Clubhouse during the Covid era. They believed in fallacies like the stock to flow model. They were also attracted to the idea that Bitcoin was not only financially sound, but morally superior too. It was better than the sh*tcoins, better than fiat. By merely tithing your Bitcoin every month, you could bring about a financial transformation to a fairer world, and when fiat and everything else collapsed, you'd be one of the chosen few to be the kings in the new world, a ruler among the ruins.
So why are they giddy about the possible obliteration of Coinbase and Binance, who have collectively onboarded 100m-200m individuals worldwide to crypto and, specifically, Bitcoin? These are de-facto crypto banks for the entire globe, and made owning Bitcoin easy and simple for tens and maybe hundreds of millions. More than anyone, these two firms have made mainstream adoption of Bitcoin possible. Why would the laser eyes cheer government attacks against them?
It's simple. The cultists are intellectually short crypto, more than they are financially long Bitcoin. For the most part, they don't actually have meaningful economic upside in Bitcoin. Since they joined in 2021/22 they mostly lost money in real terms "stacking sats". They think that they will eventually be rewarded for their piety, but for now, the amount of real goods they can buy with their sat hoard is actually dwindling. They aren't interested in Bitcoin adoption, or usage of Bitcoin increasing worldwide, because that's not what they're here for. They're here to find social kinship within an in-group of people that lives in a Bitcoiny way. They're here for the party, not for business.
So what attracts these people to Bitcoin? Simply, the secular cult. It's a way of life for people that live on the margins of society – people that would otherwise be conspiracists, goldbugs, radical libertarians, etc. Generally, they're unhappy with the status quo and find it convenient to blame central bankers and interest rates, and ultimately "fiat culture" for everything wrong with society. Whether this is financial cycles, debt, war, or even more far fetched things like culture, art, food, or fertility. It's all the fault of government spending, inflation, and the debauching effect of fiat money on society. These people believe that they can find a kind of liberation in Bitcoin, especially one that comes at the expense of their fellow man, who they believe is condemned to a kind of financial hellfire that will purge all fiat, Sodom and Gomorrah style. The great flood will come and only Bitcoin will remain. David Gerard once called the laser eye religion an “apocalyptic death cult,” and he’s mostly right. The entire ideology is premised on the End of fiat, the end of degeneracy, of debt binges, of credit, of largesse, and all of its symptoms in society, and the rebuilding of society around a more honest monetary foundation – after a period of complete destruction and anarchy, of course.
(Of course, there's a kernel of truth to everything here, but there's a vast difference between plain observations and the crafting of a literal secular cult around these ideas).
Laser eyes or Bitcoin maximalism isn't "like a religion," it's literally one. It has everything a religion has, and it makes specific claims about genesis, piety, and salvation.
There's a doctrine of absolution/salvation – any sin, no matter how heinous is forgiven if you repent, forsake sh*tcoins, and embrace bitcoin. They really mean this too – I mean look at some of the most prominent Bitcoin maxi gurus, with grim pasts involved in shilling ICOs to retail. All forgiven post Bitcoin baptism.
There's a conception myth. Bitcoin was created in a uniquely perfect and fair way, nothing else can come close to that, and nothing like that can ever exist again. Only Satoshi's divine Proof of Work and lack of premine can foster a truly global decentralized commodity money.
There's religious texts. Satoshi's original scripture, the white paper, the forum posts, and the subsequent exegesis – the Bitcoin Standard and many others.
There’s specific cultural rituals: eating meat, shooting guns, promoting masculinity, hierarchy, the nuclear family, disdaining progressivism and feminism, and endorsing a kind of ascetism and privation.
There's a tithe – stack your sats every two weeks from your paycheck and even if you're losing money (which these class of 2021 Bitcoiners generally have done), you are still doing good, because it's working for the benefit of the church of Bitcoin. (Contrary to what many people think, Bitcoinism isn’t like the ‘prosperity gospel’ strand of Christianity. In fact, it’s the opposite. Laser eye Bitcoiners actually celebrate privation, emphasizing the sacrifices they make to grow their Bitcoin stack (think of it as a financial equivalent of religious fasting). This is also why they call themselves “plebs” – as a way to claim kinship with the working class “little guy.” Again, remember that these are latecomers. They needed to find a moral high ground over the established crypto elites, that mostly made money from their participation in the space, and the pure, underprivileged Bitcoin plebs. If you lack skills or a means to contribute to the industry or to make money from it, the next best thing is to claim a kind of working class, honest virtue, by calling yourself a pleb and thus morally elevating yourself over the impure money grubbing opportunistic elites.)
There's an eschatology – the fiat apocalypse / hyperinflation / great debt bubble is coming and no financial asset will be spared, except for the Chosen One (Bitcoin). After the rapture, the Bitcoiners will inherit the earth, and a handful of sats in your wallet today will buy city blocks in the future. You may be a mere pleb today, but you are a baron tomorrow.
There's rituals: making the pilgrimage to El Salvador to make a lightning payment at McDonalds, sweltering in the heat at Bitcoin Miami to see your gurus spout platitudes on stage, paying some twitter influencer $500 for a gristly cut of steak, listening to the same six podcasts host the same dozen guests week in, week out. Trolling the nocoiners and the sh*tcoiners on twitter. Telling your own story of how you "found bitcoin" and how it gave you structure and purpose after your divorce. Recruiting new adherents to the cult.
So what does this have to do with Binance and Coinbase? Well even though these firms have done more for Bitcoin adoption and accessibility than literally any other companies in the industry’s history, they are impure, because they listed other coins. They built what people wanted, and that was tools and applications beyond just Bitcoin. The laser eyes harp about Brian Armstrong's early tweets about being focused on Bitcoin, before he learned from the market that to survive, he had to build what people actually wanted, not what a small minority of zealots insisted on. (This is why you wont find any maxis building real companies, because to be a founder is to be forced to accept market realities, rather than trying to impose your ideology forcibly on the world.)
Binance and Coinbase may have made questionable listing and product decisions (and to be clear, they're very different companies, with different regulatory strategies and risk appetites, so I don't mean to imply they are similar in that respect), but they did provide the tools for Bitcoin to achieve global adoption in a way that wasn't possible before.
But these laser eyes see the world through the lens of the sacred and the profane. They aren't focused on Bitcoin's success. They would rather live in a world of purity in which Bitcoin is marginal and niche (but all competing coins had failed), than a fallen world in which Bitcoin is much bigger, but other blockchains survived and thrived. To live in this second would would be to admit that Bitcoin wasn't Special and Uniquely Good and Moral, but it was simply a tool, one tool among others, some of which proved more successful and adaptive. If this second world came to pass, Bitcoiners would have to accept that their God was a false one, that their faith was misplaced, that their ordained future didn't and would never occur. Even if the fiat apocalypse did come, and Bitcoiners weren't uniquely saved, but others were too.
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Over the last few days I've been studying the most famous trades of all time. Arguably the most legendary trade ever was when George Soros broke the Bank of England, giving him his immortal financial reputation.
How'd he do it & how much did he make in the process? [THREAD 1/12]
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José Filippini retweetledi
WTF IS GOING ON. STOP SELLING YOU FUCKING ANIMALS
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José Filippini retweetledi
An entire MBA fits on one page.
But you better know the math cold.
Like & comment if you want the excel.
6 topics:
*1) Unit economics*
This builds from product-level unit economics to company financials.
Quantity per unit, growth in units.
Price per unit, growth in pricing.
Cost per unit, marketing spend per unit.
Get you return on ad spend (ROAS), customer acquisition cost (CAC), LTV/CAC, gross margins, unit contribution margins, and more.
This model sets up two diverging products:
A higher gross margin (GM), higher marking cost, low pricing power, low growth product.
Against a lower GM, better pricing power, better growing, lower unit market cost product.
To show how the dynamics of the two play out over time.
*2) Accounting*
Unit drivers flow into revenue, variable COGS, and variable SG&A.
Then to EBITDA, EBIT, EBT, Net income & EPS.
Simple cash flow statements & balance sheets reconcile D&A to inflation-adjusted replacement CapEx, debt levels, & GAAP PP&E.
You have to be fluent in accounting to look at public companies.
Not because accounting itself matters.
But because accounting can obscure what matters.
And your task it to translate GAAP into meaningful business logic.
*3) Operating ratios*
Unit drivers output financials, financials output overall business ratios.
Revenue growth, EBITDA growth, EBITDA margins.
Contribution margins (= change in profit over change in revenue).
Net debt-to-EBITDA, net debt % of EV.
*4) Valuation*
You can drive valuation on multiples or a DCF.
Which are equivalent:
The discount rate minus the growth rate determines the 'terminal multiple.'
Using a P/E instead of a DCF simply uses next year as the terminal value.
This model drives value from the DCF, and maps that to the multiples to show how they connect.
*5) Corporate finance & DCFs*
DCF math attached using the CAPM.
The summary is a beta from historical returns, add the cost of debt.
To get the WACC - the theoretically correct discount rate.
DCFs are extremely assumption laden - you can get out almost whatever you want.
But realistically.
Your banker (or analyst) will make the math work out to a 7-13% discount rate.
Depending on the risks, industry, markets - and what they want to achieve.
*6) Sensitivities & the hard part*
The last section sensitizes the equity value and multiples to unit and price growth.
Bringing unit drivers full circle to valuation outcomes.
Ultimately, the hard part isn't the math.
You have to be fluent in the math, its nuances and its limitations.
If not, you will lose out to those who are.
But once you are, you also have to shift focus.
To the hard part.
Which is always in filling in the numbers.
If you're investing, that means thoughtful views on unit drivers; on how, when, and why they shift.
And if you're building, it means making the numbers on the page happen.
That's all for now.
Like & comment if you want the excel.
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José Filippini retweetledi
