jsonic33

Young woman drops the most unfiltered take on what men "really" want—and it's going viral for a reason: "Men are basically all the same. They just want a nice, sweet, supportive woman. You don't even have to be that beautiful. Don't be fat, go to the gym, eat healthy, put a little makeup on—not too much. But ultimately, men want peace at home. He goes out, takes on the world, does all the hard things… and just wants to come back to food on the table, house clean, no drama." 27 seconds of brutal simplicity that either comforts or enrages people. Ladies: Do you buy this as the universal male blueprint? Men: Is she reading the room… or oversimplifying? Be honest—no judgment.

@zaidchakir 10 bodies. I wish the average was so low. Feminism has destroyed women.

As a Muslim man you have a huge advantage other men don’t have When you’re young and unmarried, you can focus on your priorities, you’re not distracted by dating, picking up girls, or wasting countless hours of time, energy, and money on random women. That is the life of the average non-Muslim. Then, when you do get married, and Allah rewards you for your patience with a good supportive virtous wife, you can progress towards your goals for your family even faster because you have a good Muslimah behind you who cares for you. Who’s not infected by feminism, who’s not going out partying and clubbing, who’s not going on girls trips doing raunchy stuff, who hasn’t racked up 10 bodies, who doesn’t have a bad attitude, etc A nice sweet feminine girl who just wants to be taken care of, wants to be cherished, and wants to make it to Jannah with you. Not attached to everything worldly, and wholly dedicated to supporting you. Once you have that, you’re legit richer than the average billionaire. Be grateful to be Muslim and take advantage of the superiority of our lifestyle

@KimeraChems @TheRealOpsGuy How does it compare to BAM 15?

Not odd, it's exactly the right question. Short answer: no. SANA's effect is creatine-DEPENDENT, which isn't the same as needing exogenous creatine. In the preclinical work the animals weren't supplemented. SANA actually raised creatine in the adipose tissue itself, and it works by binding the mitochondrial creatine kinases directly (CKMT1/2). The way they proved creatine is required at all: drain the pool with beta-GPA and the thermogenic effect disappears -- but that's pharmacological depletion, not diet. The genuinely open question is whether low baseline creatine status blunts it, or whether co-supplementing pushes it further. Nobody has run that one yet. Clean experiment for someone though.

SANA (MVD1): the salicylate derivative that turns fat cells into furnaces Most metabolic compounds in the obesity space act through appetite -- GLP-1 agonists like semaglutide and tirzepatide work on satiety signaling, so intake drops. SANA is interesting to researchers because it operates on a completely different axis: energy expenditure. Rather than reducing intake, it increases how much energy fat tissue burns. Here's the mechanism, in plain English. Fat cells are essentially storage depots -- their job is to take in energy and hold onto it. SANA appears to flip a switch that shifts them toward burning that stored energy off as heat, a process called non-shivering thermogenesis. And it runs even at rest, with nothing else going on. The engine behind that heat is creatine -- the same molecule sitting in every gym bro's shaker bottle. Normally creatine works like a rechargeable battery inside the cell: it grabs a packet of energy, stores it as phosphocreatine, and releases it wherever quick fuel is needed. An efficient little shuttle. SANA drives that same system in a "futile cycle" instead. Picture revving a car engine in neutral -- roaring, burning fuel, going nowhere, every bit of energy dumped straight out as heat. That is the effect in fat tissue: creatine charging and discharging in a loop that produces body heat rather than banking energy away. At the molecular level, SANA ramps up the machinery of creatine metabolism -- the creatine kinases and transporters that shuttle and burn it -- which pushes cellular energy expenditure up. Researchers confirmed creatine was central by depleting it: strip the creatine out and the effect disappears. That is the tell that the creatine cycle is doing the work, not some unrelated pathway. One detail that got attention: the effect held up even in thermoneutral conditions -- meaning fat cells kept burning energy as heat even when the animals were warm enough to have no thermal reason to do so. That rules out the usual cold-driven explanations and points to the compound itself flipping the switch, not the environment. The chemistry driving all of this is a nitroalkene group attached to salicylate -- the same molecular backbone aspirin is built from. That one small, reactive feature is what redirects an otherwise familiar, boring molecule down an entirely new metabolic route. It came out of years of phenotypic drug discovery: screening for molecules that measurably shift metabolism rather than starting from a preselected target and hoping. What makes it notable as a research subject: -- The effect is driven by energy expenditure rather than appetite signaling, a comparatively underexplored axis in metabolic research -- It operates independently of UCP1 and AMPK, the two classical thermogenesis pathways, which makes the mechanism genuinely novel -- In preclinical diet-induced obesity models it preserved -- and even increased -- lean mass while reducing fat mass -- Those same models showed reduced hepatic steatosis (liver fat) alongside improved insulin sensitivity and fasting glucose The data so far: SANA has been through randomized, placebo-controlled Phase 1a/b studies reporting safety, tolerability, and an early signal over a short window, with a larger Phase 2 planned. It is the first molecule reported to pharmacologically activate creatine-driven thermogenesis in vivo -- a pathway that had never been successfully drugged before. SANA (MVD1) is an early-stage investigational compound with no approved brand name and no FDA clearance, and long-term safety data does not yet exist. Kimera supplies it strictly as a research-use-only reference material -- not for human or veterinary use. A genuinely new mechanism in a field that has been running on essentially one idea. Worth watching closely as the data matures.

@ElevateBiohack @WolverineDavis Feel incredible on both . Truly.

@jsonic333 @WolverineDavis Definitely overlapping, not a replacement at all

ELEVATE Guide: O-304 (ATX-304) — A Selective PPARδ Agonist for Metabolic and Exercise-Mimetic Research This ELEVATE guide delivers an extensive, accessible deep dive into O-304, also known as ATX-304, a selective agonist of Peroxisome Proliferator-Activated Receptor delta (PPARδ). PPARδ is a nuclear receptor that plays a central role in regulating fatty acid oxidation, mitochondrial biogenesis, energy metabolism, and metabolic flexibility. O-304 was developed as a research tool to activate PPARδ in a targeted manner, promoting a shift toward fat burning, increased mitochondrial density and function, and improved endurance capacity in preclinical models. These effects mimic key aspects of endurance exercise training at the cellular and tissue level, making O-304 a valuable compound for researchers studying exercise mimetics, metabolic disease, obesity, insulin resistance, and conditions involving impaired energy metabolism or mitochondrial dysfunction. Compared to earlier or less selective PPAR agonists (such as GW501516/Cardarine or certain fibrates), O-304 is designed with greater selectivity for the δ subtype, which may reduce off-target effects associated with PPARα or PPARγ activation. Preclinical data indicate robust increases in fatty acid oxidation, mitochondrial biogenesis markers, and performance in endurance-related tasks, often with favorable shifts in lipid profiles and insulin sensitivity in metabolic stress models. This guide walks through the science step by step with clear explanations and everyday analogies so readers at any level can follow the mechanisms and research implications. We cover: •The role of PPARδ in metabolism and why selective agonism is scientifically interesting. •Detailed mechanisms of O-304, including transcriptional regulation of fat oxidation genes, mitochondrial biogenesis via PGC-1α, and metabolic reprogramming. •Head-to-head comparisons with other PPAR agonists and metabolic modulators (e.g., GW501516, SLU-PP series, SANA/MVD1). •Summaries of preclinical research findings across metabolic, mitochondrial, and performance models. •Practical research frameworks for studying O-304, including model selection, dosing considerations, key readouts, and combination strategies. •Honest discussion of limitations, including the current state of evidence (primarily preclinical), context-dependence of effects, and the importance of rigorous controls. Content shared by ELEVATE is intended solely for educational and informational purposes and should not be construed as medical advice. All statements, opinions, and recommendations expressed are our own. For research and laboratory use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. #ELEVATEBiohacking #O304 #ATX304 #PPARdelta #ExerciseMimetic #MetabolicResearch #ResearchUseOnly #EvidenceBasedOptimization #BiohackingScience #LongevityResearch #MetabolicHealth #PeptideResearch elevatebiohacking.com/2026/07/13/ele…

@WolverineDavis Can u source and sell in bulk? I will purchase 😎😎

@jsonic333 It's actually the amount that they used in the phase 1 human trials. They found it was well tolerated and are actually using larger doses in the next trials. cambrianbio.com/news-and-publi…

So I am currently taking ATX 304 (O-304 ) for about 3 weeks. It is absolutely incredible for work capacity during workouts. I am taking 400 milligrams a day like they did in the recent phase 1 human trials. My cardio output and intense exercise is absolutely phenomenal. I hardly need to rest in between sets. I do more reps with less struggle I don't need to breathe as much oxygen in between my intense sets whatsoever. Intense exercise like sled push heavy sandbag carries, assault bike intervals.. none of that gets me breathing heavy with his compound. I sleep way better I've lost 7 pounds. I accomplish way more during the day. And here's the thing, I feel no stimulant whatsoever.. I actually feel nothing But but I'm able to perform at incredible levels.

@NocturnalNelly 200mg, they sell it as 50mg capsules. Where do u buy in bulk?

NEW COMPOUND ADDED: ATX-304 - 4d half life ~3wks to steady state - Currently in Human Trials - 200mg Start (low) Really deserves a full breakdown, very interesting drug. Here's some cliff notes: 1) Potent AMPK activator W/O a drop in ATP 2) Mitochondrial signaling (Cleanup / Rebuild) 3) Increased metabolic rate 4) Potential longevity advancement, seems to be by far the best AMPK activator available mechanistically 5) Mimics fasting W/O actually fasting Not the play if you're trying to put on muscle, directly opposes that.

@chucktownSC854 @WolverineDavis Enclomophine. Plus gh peptides FTW

@WolverineDavis Hey Sean are there any peptides that boost testosterone like TRT?

@ElevateBiohack @WolverineDavis It's both but I looked it up and it doesn't replace GW - whatever either It's complimentary there's some overlaping mechanisms but different.

If we’re being precise, ATX-304 is a pan-AMPK + mitochondrial activator that produces robust PPARδ-overlapping metabolic effects. AMPK and PPAR pathways have real crosstalk in cells. Activating AMPK can enhance or feed into PPARδ-mediated gene programs around fat oxidation and mitochondrial function.

@toosteeptofail @Mericamemed No I would say the great vast majority of men don't think that way at all. They find a mate who they like and are like great now I can build a life and have kids etc. They're not always wondering can I get someone one percent hotter I mean what the actual ****

@Mericamemed I find it funny that they always have to add the "especially as a woman" line. What exactly makes this "especially" different as a woman? Are men not in the exact same boat?

Women will hit on 21

@ElevateBiohack That's a fantastic read! Could researchers pair it w GW-5? Even though they are similar?.

@BlackPilledPaki Holy F.

Apocalyptic Hypergamy: Mid looking whore wasn't fulfilled in her marriage so cheats on her Scandinavian Chad husband who forgives her and takes her back

@PressSec @AwakenedOutlaw Omfg. F off. America only.

America has lost a Statesman. President Trump and the White House have lost a friend. Rest in Peace, Senator Graham.

@ElevateBiohack Dude was this may or June? It was May will you update June's numbers?

Here’s the ELEVATE communities favorite products from Kimera this month. Full Ranked List! 1. SLU-PP-915 — 51 units 2. Seltorexant — 29 units 3. BPC-157 — 24 units 4. Bromantane — 21 units 5. Sterile Research Diluent Non-USP (0.9% Benzyl Alcohol in Purified H²O) — 19 units 6. Flmodafinil (CRL-40,940) — 18 units 7. SLU-PP-332 — 18 units 8. SANA (MVD1) — 14 units 9. GHK-CU — 13 units 10. Methylene Blue — 11 units 11. Selank — 10 units 12. KPV — 10 units 13. Fenbendazole — 10 units 14. BPC-157 TB-500 KPV GHK-Cu (KLOW) — 9 units 15. BPC-157/TB-500/GHK-CU (GLOW) — 8 units 16. 5-Amino/MIC — 8 units 17. GW-501516 — 7 units 18. 5-Amino-1MQ — 7 units 19. MOTS-C — 7 units 20. Bioregulators — 6 units 21. TB-500 — 5 units 22. NAD+ — 5 units 23. MK-2866 (Ostarine) — 5 units 24. Enclomiphene — 5 units 25. O-304 (ATX-304) — 5 units 26. Noopept — 4 units 27. Melanotan I — 4 units 28. GB-115 — 4 units 29. BPC-157/KPV/GHK-CU Transdermal Serum — 4 units 30. CL-316243 — 4 units 31. Mildronate — 3 units 32. Aminotadalafil — 3 units 33. MDS-31 — 3 units 34. CE-123 — 3 units 35. DIHEXA — 3 units 36. Oxytocin — 3 units 37. TAK-653 — 3 units 38. YK-11 (Myostine) — 3 units 39. LIPO-MIC PRIME — 2 units 40. MK-777 (Acetamoren) — 2 units 41. Ipamorelin — 2 units 42. ISRIB — 2 units 43. MPAP — 2 units 44. Thozalinone — 2 units 45. RAD-140 (Testolone) — 2 units 46. AOD-9604 — 2 units 47. AC-262 — 2 units 48. Formulas/Blends (Discounted/Clearance) — 2 units 49. Nortadalafil — 2 units 50. LIPO MIC/NAD+ — 2 units 51. PPAP (Phenylpropylaminopentane) — 2 units 52. Acetic Acid 0.6% — 2 units 53. TH9507 — 2 units 54. Phenylpiracetam Hydrazide — 2 units 55. Oxiracetam — 1 unit 56. J-147 — 1 unit 57. N-ethyl Tadalafil — 1 unit 58. ATPLEX — 1 unit 59. HBT1 (YDL233C) — 1 unit 60. Survodutide — 1 unit 61. Melanotan II — 1 unit 62. MID-35 — 1 unit 63. L-Carnitine — 1 unit 64. Endoxifen — 1 unit 65. DMSO — 1 unit 66. ITPP (Myo-inositol trispyrophosphate) — 1 unit 67. KIMERA-VASC™ — 1 unit 68. N163-166 mod6 — 1 unit 69. HERC (MTB) — 1 unit 70. MNT (PMP) — 1 unit 71. Tropisetron HCL — 1 unit 72. Alpha GPC — 1 unit 73. MK-677 (Ibutamoren) — 1 unit 74. CJC-1295 No DAC/Ipamorelin — 1 unit 75. 9-ME-BC — 1 unit 76. Coenzyme Q10 — 1 unit 77. Thymosin Alpha-1 — 1 unit 78. Fladrafinil (CRL-40,941) — 1 unit 79. Phenibut — 1 unit 80. CDP-Choline (Citicoline) — 1 unit 81. CMS-121 — 1 unit 82. LGD-4033 (Ligandrol) — 1 unit 83. S-4 (Andarine) — 1 unit 84. Mirodenafil — 1 unit 85. Modafiendz — 1 unit Notes: •SLU-PP-915 is the clear top seller by a wide margin (51 units). Strong performers in the peptide/nootropic space: Seltorexant, BPC-157 (including blends), Bromantane, and the two SLU-PP compounds. Research diluent and foundational items like Methylene Blue, Selank, KPV, and Fenbendazole also moved well in double digits.

@Cr7Godbrand @fortytooo The problem.

Women are the enemy of civilizations because their loyalty is to survival, not principles. Women’s moral conscience is lower than men’s because their psychological development is based on shame, not guilt. Men feel guilt as an inner punishment, while women feel shame as fear of outside judgment. Because of this, women’s behavior is driven by social survival rather than principles. This is why people say a woman has the prerogative to change her mind. This leads to a lack of accountability and an inability to accept the truth. No matter how well arguments are presented, women hate the truth. Women understand the world through their feelings, which causes shifting standards. Because of this lack of reason and logic, civilization cannot survive under female leadership. Men build and women consume. Men build civilization, while women build families. When women rise in power, civilization collapses, as the proverb says, “the hen does not herald the morning.” Women belong at the heart of the family because of reproduction. Men continue in their role as warriors, protectors, and providers at the family and national level. Women are supposed to support society through reproduction and promoting family, but they are not doing so. This is a failure of duty to society. The feminist desire to win without a clear goal and without understanding consequences weakens the state. The state becomes weak and is then conquered by stronger forces. Women should not vote or hold positions of national importance.

@susylicious2023 Assuming the story is true which it probably is. He needs to leave her ass. She'll find out real quick. There's no way in hell I would have put up with that.

I deliberately reduced my workload to prove a point to my wife.

@TaraBull Skank

Actress Charlize Theron greets fans at the French premiere of The Odyssey in Paris

@BasedMikeLee @hollywood2pt0 Because of insane treason.

Excellent question

@AndrewMarotta8 @cocagroyp U r cooked. Women are different now. It's not 2015 anymore. I wish it was.

@cocagroyp These internet personalities can't conceptualize a relationship that isn't based on vapid statistics and instead about having a unique RELATIONSHIP with that person... fucking idiots.

Nick Fuentes reminds everyone that: YOUR GIRL IS GOING “It doesn’t matter how powerful you are, how good looking you are, how athletic you are, how much status you have, your girl’s going.” 😉