Sean Davis ⚡ Built For Life.

After our Anniversary Sale donation on Cinco de Mayo, the team at Blessed Sarnelli House sent me this photo. This is in the backyard of their brownstone in Kensignton, PA on Kensignton Ave. St. Joe’s Prep students and volunteers were preparing tacos for people in need… and they printed out the Wolverine logo and took this picture for us! That means more to me than I can explain.♥️ Research With Purpose isn’t just a slogan. It’s becoming something real. Thank you to every single person who has supported Wolverine. You helped make this happen. God Bless!

@jsonic333 It's actually the amount that they used in the phase 1 human trials. They found it was well tolerated and are actually using larger doses in the next trials. cambrianbio.com/news-and-publi…

@WolverineDavis Why are u taking so much? That like a bottle a week?? Why sell it in 50mg capsules.

So I am currently taking ATX 304 (O-304 ) for about 3 weeks. It is absolutely incredible for work capacity during workouts. I am taking 400 milligrams a day like they did in the recent phase 1 human trials. My cardio output and intense exercise is absolutely phenomenal. I hardly need to rest in between sets. I do more reps with less struggle I don't need to breathe as much oxygen in between my intense sets whatsoever. Intense exercise like sled push heavy sandbag carries, assault bike intervals.. none of that gets me breathing heavy with his compound. I sleep way better I've lost 7 pounds. I accomplish way more during the day. And here's the thing, I feel no stimulant whatsoever.. I actually feel nothing But but I'm able to perform at incredible levels.

It's an AMPK network activator. The downstream signaling overlaps with PPARδ-regulated metabolic pathways rather than acting as a direct PPARδ agonist. Personally, I've noticed a significant improvement in my work capacity and stamina at 400 mg/day, but that's just my own experience.

@ElevateBiohack @WolverineDavis It's both but I looked it up and it doesn't replace GW - whatever either It's complimentary there's some overlaping mechanisms but different.

ELEVATE Guide: O-304 (ATX-304) — A Selective PPARδ Agonist for Metabolic and Exercise-Mimetic Research This ELEVATE guide delivers an extensive, accessible deep dive into O-304, also known as ATX-304, a selective agonist of Peroxisome Proliferator-Activated Receptor delta (PPARδ). PPARδ is a nuclear receptor that plays a central role in regulating fatty acid oxidation, mitochondrial biogenesis, energy metabolism, and metabolic flexibility. O-304 was developed as a research tool to activate PPARδ in a targeted manner, promoting a shift toward fat burning, increased mitochondrial density and function, and improved endurance capacity in preclinical models. These effects mimic key aspects of endurance exercise training at the cellular and tissue level, making O-304 a valuable compound for researchers studying exercise mimetics, metabolic disease, obesity, insulin resistance, and conditions involving impaired energy metabolism or mitochondrial dysfunction. Compared to earlier or less selective PPAR agonists (such as GW501516/Cardarine or certain fibrates), O-304 is designed with greater selectivity for the δ subtype, which may reduce off-target effects associated with PPARα or PPARγ activation. Preclinical data indicate robust increases in fatty acid oxidation, mitochondrial biogenesis markers, and performance in endurance-related tasks, often with favorable shifts in lipid profiles and insulin sensitivity in metabolic stress models. This guide walks through the science step by step with clear explanations and everyday analogies so readers at any level can follow the mechanisms and research implications. We cover: •The role of PPARδ in metabolism and why selective agonism is scientifically interesting. •Detailed mechanisms of O-304, including transcriptional regulation of fat oxidation genes, mitochondrial biogenesis via PGC-1α, and metabolic reprogramming. •Head-to-head comparisons with other PPAR agonists and metabolic modulators (e.g., GW501516, SLU-PP series, SANA/MVD1). •Summaries of preclinical research findings across metabolic, mitochondrial, and performance models. •Practical research frameworks for studying O-304, including model selection, dosing considerations, key readouts, and combination strategies. •Honest discussion of limitations, including the current state of evidence (primarily preclinical), context-dependence of effects, and the importance of rigorous controls. Content shared by ELEVATE is intended solely for educational and informational purposes and should not be construed as medical advice. All statements, opinions, and recommendations expressed are our own. For research and laboratory use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. #ELEVATEBiohacking #O304 #ATX304 #PPARdelta #ExerciseMimetic #MetabolicResearch #ResearchUseOnly #EvidenceBasedOptimization #BiohackingScience #LongevityResearch #MetabolicHealth #PeptideResearch elevatebiohacking.com/2026/07/13/ele…

@DigitalFringed1 @barbarianfitco make that half shirt bro and turn it into a shimmel

@barbarianfitco Hell yea brotha. Needed something a little dark red. Looks sick.

@DigitalFringed1 digging this color combo. It’s giving old school college athletics. Nice choice, bro!

@ElevateBiohack Cambrian Bio owns ATX304 cambrianbio.com/news-and-publi…

@ElevateBiohack Brother ATX304 is not a PPARδ Its an AMPK activator pubmed.ncbi.nlm.nih.gov/38749175/

@DispoH3R0 #newprofilepic

Caught being Italian af in the wild

@DispoH3R0 Lemme see dem feet!

Jfc I lost 7 lbs on vacation not tracking 2mgs reta 10mgs tirz I’m actually disappointed cause I ate till I blew way past the glp activation, atleast once a day

@nateyamasaki Yes bro, I drink a can of tuna everyday. I should try the sardine thing

For some of us, it begins, although I’m not sure if it’s a fad, normal diet to some cultures Been looking to add more EPA+DHAthrough natural means Anchor stack food a few times a week? Maybe if I can figure out a decent pairing Always been a fan of food > supplementation

Every heartbeat, every rep in the gym, and every step you take is powered by one tiny molecule: ATP. In this video, I break down the difference between ATP, ADP, AMP, and AMPK in simple terms so you can finally understand how your cells produce and manage energy. Understanding these basics makes it much easier to understand why scientists are so interested in exercise, mitochondria, and emerging metabolic therapies.

@brentlajeunesse Looking good bro. Lean machine

Bastille Day. They stormed the prison and took their freedom by force. Men over 50: storm your own today. Break out of low energy, excuses, and the story that it’s too late. Heavy iron. Savage discipline in the gym. I’m 58 and still forging mine right now. What are you storming? Drop it below. #BastilleDay #FitOver50

Yes bro. The chart speaks volumes

@BhavanChand yes bro

"Fix your basics first before using GLP-1s" But GLP1s literally help you fix your basics

They mostly are 50mg caps. And I took one 50mg for a day or two and did notice a difference. But then I dug into the research and saw they are doing human trials at 400mg and getting incredible results. And there was a human trial in Sweden years ago that did 1000mgs Also the Cambrio trials now show that 400mg was well tolerated and are now starting trials with larger doses. It is expensive to research with that much.

@WolverineDavis @nicknorwitz Have you tried lower doses? Suppliers I've found are in 50mg pills, and at 400mg per dose that wouldn't last long and be expensive

1/7) This is, without a doubt, the craziest “diabetes drug” ever invented. It’s completed Phase II human clinical trials showing efficacy for reducing blood sugar and improving blood pressure. But the promise may extend far beyond that. In preclinical trials, it: • Reduces fatty liver • Increases energy expenditure • Improves exercise endurance • Cuts fat without sacrificing muscle It’s called ATX-304. But how does it work?

@chucktownSC854 Hey 👋 No, you just need to get TRT. There's not a peptide that effectively does that

@WolverineDavis Hey Sean are there any peptides that boost testosterone like TRT?

@BodyRecompExprt Good stuff, thanks

How to influence someone's behavior by swapping these 2 words Watch this to be more successful in sales, persuasion, and coaching change

@MogLifeLabs @DocAbirHealth yes bro, we are blessed to have these tools

@DocAbirHealth I owe more than I’d like to admit to GLP

This is one of the reasons GLP1s are such a game changer for many. Quietening the food noise so that you can make sensible decisions is unmatched. So many of us struggle with this very issue. It’s not easy to “have a little bit” or “just one” and then stop. When you are in total control and can logically make the choice “do I want to eat this?” when it’s something off plan is incredibly important. No guilt. No shame. No hating yourself. Just making a sensible decision. It’s a lot easier to incorporate little enjoyable things here and there than it is to go all out on one day or the entire weekend.