Joe Todisco

Ken Griffin is the American story. A kid trading out of a dorm room, who went on to build Citadel LLC into a global powerhouse. He didn’t inherit it. He built it. Took risk. Won. And what’s the result? More than 2,500 jobs in New York City. Over $2.3 billion in taxes paid to New York. Over $650 million in philanthropic contributions tied to this city. Thousands more jobs coming from major development projects. That’s not rhetoric. That’s impact. But instead of learning from that success, some politicians would rather demonize it. Because tearing people down is easier than building anything yourself. So let’s be very real: If Ken Griffin and firms like his leave New York… who replaces 2,500 high-paying jobs? Who replaces billions in tax revenue? Who funds the services you claim to care about? A government-run grocery store? That’s not economic policy. That’s fantasy. And to @ZohranKMamdani What have you actually built? How many jobs have you created? How many people depend on you for a paycheck? What real risk have you ever taken? We need builders. Not people who attack them.

@NJGov Its not a good joke if all of your constituents are excited about it and then its just a big joke to you. This obviously makes sense to most of NJ

Today, we are announcing plans to lift the statewide ban on self-service gas stations in New Jersey. We encourage New Jerseyans to familiarize themselves with gas pumps as this change is in effect immediately, April 1, 2026.

@EricTopol @bmj_latest @zalaly @Biostayan So reading this as what happens when people with type 2 diabetes stop taking their medication? The headline is deceiving, implies that the increased CV risk is tied to drug use as opposed to failure to manage a chronic condition

A new finding after stopping GLP-1 drugs in a large cohort with Type 2 diabetes: rapid erosion of CV benefit/protection New @bmj_latest by @zalaly @Biostayan bmjmedicine.bmj.com/content/5/1/e0… See thread: x.com/zalaly/status/…

I echo these sentiments. There are some really good people at both FDA and CMS working to make changes that genuinely help patients, increase access and/or reduce drug costs.

The biggest misunderstanding about pharma is that the PBM is the gate keeper to the patient. You pay the toll, or you don’t get access. The toll is a rebate.

In all my years of broadcasting, I'd never gotten emotional on air until tonight. It was impossible to hold back the tears. Jack Piccione of Tappan Zee lost his father suddenly last Sept. 1. Matthew Piccione died of a heart attack minutes after playing pickleball with friends. He was 51. Over the last three years, I got to know Matthew Piccione fairly well. One day back in 2023, he asked coach George Gaine for my number so he could call me just to say thank you for calling out Jack's contributions during Tappan Zee's championship run. Jack was a role player who averaged maybe 5 points a game as a freshman. But he started and never came off the court. "I know he doesn't score a lot of points," Matthew Piccione said. "But you are one of the only people who appreciates what he does for the team." Matthew Piccione kept a very low profile at games and reinforced in his son to be the emodiment of all the things that make Tappan Zee basketball different than any other program in the state. Play unselfish. Defend. Be coachable. Defend. Draw charges. Pass. Sacrifice for your teammates. And, of course, defend some more. Nobody in the history of Tappan Zee basketball since I have been covering has ever played that role better than Jack Piccione. He's the best best defensive player in the program and is on an elite level of players I've been around in Section 1. When Matthew died in September, I worried about Jack. I wondered what his senior season might be like. The person most responsible for instilling and reinforcing the values that made Jack great was now tragically gone. Tonight, Jack Piccione scored 5 points in the Section 1 Championship game. FIVE. Yet not only did his team because of his performance, I had the honor of handing him the MVP Trophy to prove it. In the final 90 seconds of the game, I shared the story of Matthew Piccione and his passing. You will hear the emotion in my voice. It's genuine, not because of any relationship I had with him. You just can't be a sports parent and not relate to loving your child and always wanting what's best for them. Because here's what I am going to tell you. And I really want all parents to read this and remember it: Your kids' youth - not just athletics, but all of it - is short and it's precious. You don't get this time back when it's over. It goes way too quick. And some don't even get to see it to the end. You have a choice: You can spend this period of their lives stressing about how many points they score, what awards or accolades they receive, begging people to vote in the online poll for Player of the Week, emailing the coach and complaining about playing time or lamenting the number of shots they get in a game. Go ahead. You can make all of that important for yourself and your child. Trust me, you won't be alone in doing so. Or you can do what Matthew Piccione did. Sit in the stands and enjoy watching your children compete. Teach them that it's team above all else, stress what it means to sacrifice and ensure them that, when you do those things and have success, the feeling of hanging a banner will far exceed any of the personal accolades think are important. And, sadly, God might choose that you won't be around to see it all anyway. Matthew didn't get to give his son a hug after he won tonight. And Jack didn't get to see the pride in his father's face. Think about that. If you are a parent, try to put your child in Jack's shoes. If God forbid your child was confronted with the same tragedy, you'd want them looking back on this sacred period of their lives the way Jack will forever recall them with his dad. Tonight was complete validation for Jack Piccione and all of the things his father always told him. Jack scored 5 points and won the MVP on his way to becoming the most decorated basketball player in Tappan Zee history. Nobody has ever won more in a TZ uniform than the most unselfish player they've ever had. He wouldn't trade his career with anyone, either. Take a moment to listen to myself and Pleasantville coach Nick Bonura from tonight's @SportsEngine broadcast of @TZeeAthletics @TZhoops

Please, please do this. If Congress does nothing else, other than KCAPA bill, do this

@mcuban @costplusdrugs I wish you luck and hope you succeed. If you can get your conversion cost under $6/1000 you have a shot.

@jt034 @costplusdrugs We aren’t installing it in our sterile plant. We have modularized our manufacturing. We use robotics and can turn a line in hours. What I will tell you is that we can sell the tablets for the same or less than what we do today , when we manufacture it ourselves. Ex- ANDA fees

Thank you ! Some thoughts. @costplusdrugs has the ability to manufacture generics here in the USA. Doesn’t matter whether they are OTC or prescription. The ingredients, their cost and the cost to manufacture, are exactly the same. We did the math. We can bring tablet manufacturing of generics to the USA. Take us about a year. But we can’t. If we want to manufacture 1,000 new drugs and get ANDAs for them , that’s 365m in fees to the FDA. (365k ea). Waive those fees. We will be up and running and selling them on CostPlusDrugs.com and TrumpRx for the same or less than it costs for those made overseas ! Thank you for your consideration !

I don’t doubt your ability to install an oral solid line in your small scale sterile plant and make a few products, what I doubt is your ability to manufacture 100 drugs (let alone 1000 drugs) at a scale sufficient to generate cost efficiency better than your current suppliers. What is your projected conversion cost per 1000 tabs (excluding raw materials and API)?

@jt034 @costplusdrugs We know exactly what we are doing. We already have a robotics driven manufacturing plant in dallas. We make sterile injectibles and biosimilars. We know how to add tablets.

Generic drugs just can’t be made here as cheap as India, but they don’t have to be. $5/100 is a reasonable price, but as long as CVS can pick the cheapest supplier, they will always go overseas. The solution is a law that says for any Medicare or Medicare patient, if a US made product is available, it must be given first.

@jt034 @mcuban @costplusdrugs What about not "now" but a long term play with a hybrid approach in the interim? US drug making may cost more upfront ($4-5/bottle vs $1 abroad) but overall it should cuts shortages, adds jobs & GDP to offset.

@mcuban @costplusdrugs And I would add to this that global Indian players like Aurobindo and Lupin are vertically integrated in at least the top 100 APIs, can make a 100ct bottle for less than $1.00 including API, where same drug in US costs $4-$5/100ct.

Respectfully @mcuban you have taken a fairly naive and dismissive view of the level of labor and sophistication required to develop and manufacture generic drugs. I applaud what you have done for distribution, and what you are trying to do relative to PBMs, but manufacturing generic drugs is not like making candy. Waiving GDUFA fees alone will not give Cost Plus Drugs the ability to manufacture 1,000 drugs within a year. Some issues to consider: 1. Where are you getting formulations, doing bioequivalence testing ($500k per drug assuming you pass), and generating 12 months realtime stability data to file an ANDA? Even if you acquire already approved ANDAs, tech transfers take time and money. Developing formulations that meet FDA guidelines for QBD take time and money. 2. Who is reviewing these 1,000 ANDAs at FDA in a timely manner? The purpose of GDUFA was to generate funding for generic drug review at FDA. Prior to GDUFA, ANDA reviews were 3-4 years. Will congress appropriate $100mm for OGD if Trump waives GDUFA fees? 3. Where are you sourcing raw materials and APIs? You need a global sourcing network to secure all APIs at a reasonable cost. You need a quality team to audit all of your API suppliers, do OOS investigations, etc. 4. How many sites will you need to manufacture 1,000 drugs at a large enough scale to be cost effective? I estimate you will need 5-7 large scale sites, all equipped with QC labs, stability chambers, etc.. Billion dollars of equipment and capex. 5. Will you sell to the big 3 or only through your captive pharmacy? Unless you negotiate to sell to retail pharmacy, you will end up writing off a lot of inventory that you had to make to bring production costs down (large scale batches to bring down per pill costs). These are just a few issues that come to mind.

For the first time in @HolmdelHS @HolmdelHornets history, the boys Varsity Football team @holmdelhornetfb is ranked Top 20 in the State!!!!! nj.com/highschoolspor…

@NJ_MVC it takes 6 points of ID to get a Real ID, but then to register my car the Real ID only counts for 1 point of ID. Shouldn’t really ID count as 6 points?

This is accurate

Just in time for Mother’s Day Holmdel Football fans!!! Buy a ticket for charity and win your wife or mom an amazing gift

@Matt_Smith56 Congrats Matty, you are going to a great school and football program

Official. Go Gate

@BillAckman @MrStand_Fast So the biggest question I have is why the military would conduct training missions in the landing path of DCA instead of somewhere over Chesapeake Bay

@MrStand_Fast Thank you. Helpful.

Someone who has piloted a Blackhawk please explain how this is possible.

Hoya Saxa

Barstool Pizza Review - TinyBrickOven (Baltimore, MD)