Kosuke Kato

@tferriss @foundmyfitness Really enjoyed your conversation with Dr. Patrick! Just a quick clarification: the psilocybin dose was 5mg/kg, not 5mg per mouse. I believe our initial press release may have left out the unit. Appreciate the mention.

Rhonda Patrick on how to reverse 20 years of heart aging. cc: @foundmyfitness

@hubermanlab Highly recommend his episode on psilocybin, a clear, balanced discussion of both potential benefits and risks. youtu.be/eIxVfln02Ss?si…

Psychedelics used to be so edgy to talk about. Now, federal tax $ is used to study their effects in mice & there are human clinical trials completed & ongoing. People are discussing psilocybin for longevity. MDMA & ibogaine likely to gain FDA approval soon. Things. Have. Changed.

シロシビン (psilocybin) に老化抑制作用!? 私たちの研究により、シロシビンとその代謝物シロシン (psilocin) が、 -細胞寿命の延長 -老齢マウスの生存率改善 を示すことが報告されました。 精神医学を超えた、再生医療・抗老化の可能性を提示しています。

A study in @Nature_NPJ Aging provides evidence that treatment with psilocin, the active metabolite of the psychedelic psilocybin, extends cellular lifespan and psilocybin treatment promotes increased longevity in aged mice. go.nature.com/454uJCH

@bcmhouston Looking forward to continued collaboration here at BCM as we advance the science of psilocybin and longevity!

A recent preclinical study shows psilocybin may help slow down cellular aging. bit.ly/4kSo9Fb #aging #psychedelics

@EmoryMedicine @EmoryDeptofMed @EmoryBrain @bcmhouston Grateful for Emory’s support in enabling the first longitudinal study of psilocybin. Looking forward to continued collaboration and discovery together.

School of Medicine @EmoryDeptofMed, @EmoryBrain & @bcmhouston researchers identified psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms, actively delays #aging in cells & organisms, extends lifespan. Article ➡️ bit.ly/45YVCKm

シロシビン (psilocybin) に老化抑制作用!?
私たちの研究により、シロシビンとその代謝物シロシン (psilocin) が、
-細胞寿命の延長
-老齢マウスの生存率改善
を示すことが報告されました。
精神医学を超えた、再生医療・抗老化の可能性を提示しています。 論文はこちら nature.com/articles/s4151…
#老化 #再生医療 #サイケデリック #シロシビン #npjAging #psilocybin

Get High or Die: Antiaging Properties of Magic Mushrooms Demonstrated in Professional Study forum.worldhealth.net/articles/get-h… via @WorldHealth_Net

@PaulStamets Thanks for sharing our paper!

Could psilocybin could become a monthly neurotropic at high doses and/or a near-daily neurotropic vitamin at low doses? So exciting for this to be further explored. Will the U.S. government fund research? I hope so! Read more about this study: nature.com/articles/s4151…

'I was floored by the data': Psilocybin shows anti-aging properties in early study livescience.com/health/ageing/…

@DrGlorioso Thanks for featuring our new paper in your article!

Magic mushrooms and longevity (new studies) Contextualizing new studies that point to lifespan and healthspan extending properties of psilocybin mushrooms People have been asking me about magic mushrooms and Alzheimer’s treatment for a few years now and at first I was admittedly pretty skeptical. People with Alzheimer’s sometimes experience hallucinations and disorientation, which is not helpful for them or their care givers. Giving them a drug that could make that worse seemed to me like a pretty bad idea. About four years ago, I was looking at the data that was coming out of our platform of genes that relate to slow-brain aging and lo and behold, one of the brain receptors (5-HT2A receptor) that psilocybin mushrooms act upon, was pretty close to the top of that list. This was a piece of our own evidence that magic mushrooms, or other drugs that work through that receptor, might increase health of the brain... That’s when I started to pay attention. This past week a study came out in Nature Aging, which showed a 30% lifespan extension in aged mice given psilocybin. Additionally, a few months ago a small study showed decreased symptoms in people with Parkinson’s disease who had just one dose of magic mushrooms. Prior to the last few months, there have been >150 ongoing or completed clinical studies of psilocybin for mental health (depression, anxiety) in humans with pretty positive results. So while I wouldn’t say that I’m convinced— I’m a scientist after all and that bar is pretty high— I would say that I’m feeling pretty optimistic about the potential of psilocybin or analogue drugs to improve brain health or even extend lifespan. Should we all be taking psilocybin mushrooms? If so, what dose and how often? Are there versions of psilocybin drugs that retain the health benefits without the hallucinations?... Summary In summary, there is mounting, though early, evidence that psilocybin (and potentially other psychedelics) can lessen depression, anxiety, addiction, improve cognition, and even extend lifespan. This could be through their action on the 5HT-2A receptor or other receptors in the brain or telomere lengthening. Researchers are working on non-hallucinogenic forms of these drugs that may be available in the future. If you’d like to try them yourself (if you live in a location where they are legal), it seems like taking a standard dose every 1-2 months has the most evidence for health benefits. Read More: drglorioso.substack.com/p/magic-mushro…

Magic Mushrooms Promote Longevity Exploring Psilocybin's Extend Cell Li... youtu.be/a1fbrcEJQAc?si… via @YouTube

@rv_sehgal Nice summary

Is psychedelic medicine the next frontier in aging? Psilocybin preserved telomere length, activated SIRT1, and improved fur quality in 19-month-old mice. 🐭 #Geroscience #Psychedelics #Telomeres 🔗 nature.com/articles/s4151…

Psilocybin treatment extends cellular lifespan and improves survival of aged mice 👉 “We provide the first experimental evidence that psilocin (the active metabolite of psilocybin) treatment extends cellular lifespan and psilocybin treatment promotes increased longevity in aged mice, suggesting that psilocybin may be a potent geroprotective agent.” nature.com/articles/s4151…

Psilocybin treatment extends cellular lifespan and improves survival of aged mice nature.com/articles/s4151…

Psilocybin treatment extends cellular lifespan and improves survival of aged mice | npj Aging nature.com/articles/s4151…

Can you take an FDA-approved oral drug for Multiple Sclerosis, make it into an inhaled form, and potentially cure an entirely different disease? – Our research says you can! Check out our recent findings on drug re-purposing by lead author @kosukekatophd pubmed.ncbi.nlm.nih.gov/35326142/

Cigarettes Make You Weak: RANKL/RANK Link Changes in Muscle and Bone ✅ Just Accepted 🔗 ow.ly/LCxW50E3iOw

How is biological age calculated & can it be reset? 💪 Interesting new paper @ImpactJrnls #aging #health #medicine tinyurl.com/wze6hrd6