


LYACTS-CIRI
129 posts

@lyacts
LYmphocyte ACtivaTion and Signaling. Team leader Dr Thierry Walzer






Jeanpierre, Cognard, @FRLab1, @AlexandreBelot, Mathieu @CIRI_Lyon et al. performed exome sequencing in pediatric systemic #lupus and Evans syndrome and identified six novel monoallelic PTPN2 mutations, impairing its regulatory function. hubs.la/Q02HrHBb0 #autoimmunity

Jeanpierre, Cognard, @FRLab1, @AlexandreBelot, Mathieu @CIRI_Lyon et al. performed exome sequencing in pediatric systemic #lupus and Evans syndrome and identified six novel monoallelic PTPN2 mutations, impairing its regulatory function. hubs.la/Q02HrHBb0 #autoimmunity

Jeanpierre, Cognard, @FRLab1, @AlexandreBelot, Mathieu @CIRI_Lyon et al. performed exome sequencing in pediatric systemic #lupus and Evans syndrome and identified six novel monoallelic PTPN2 mutations, impairing its regulatory function. hubs.la/Q02HrHBb0 #autoimmunity


Excellent review on monogenic SLE: link.springer.com/article/10.100…




Thierry Walzer porte un projet financé par la Fondation ARC qui vise à mieux comprendre les liens entre cancer et vieillissement du système immunitaire. Il est revenu pendant l'émission Têtes Chercheuses sur le rôle du système immunitaire. L'émission : ow.ly/88sC50QzC6z








A study suggests that prepandemic and SARS-CoV-2–negative cases that are indistinguishable from MIS-C are characterized by Vβ21.3+ T-cell expansion and may be triggered by other pathogens. Read the full correspondence: nej.md/49SwOTT

A study suggests that prepandemic and SARS-CoV-2–negative cases that are indistinguishable from MIS-C are characterized by Vβ21.3+ T-cell expansion and may be triggered by other pathogens. Read the full correspondence: nej.md/49SwOTT

A study suggests that prepandemic and SARS-CoV-2–negative cases that are indistinguishable from MIS-C are characterized by Vβ21.3+ T-cell expansion and may be triggered by other pathogens. Read the full correspondence: nej.md/49SwOTT


Thrilled to share our paper in @NEJM on pre-COVID and SARS-CoV-2 negative MIS-C. This condition predates the pandemic but was incredibly rare and often misdiagnosed as Kawasaki Disease Shock Syndrome or Toxic Shock Syndrome without identified bacteria nej.md/49SwOTT 🧵

