Maanav Khaitan
6K posts
v interesting work from Kalyan and Rohil on reducing controllable risk in clinical trials. hopefully we see more high-risk biology being funded
Kalyan Palepu@kalyanmpalepu
Many of the most important drug classes in modern history were nearly abandoned by their financial backers. If we can solve the structural risk-aversion that almost prevented these drugs from getting to patients, then we can dramatically accelerate medical progress.
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I have learned everything I know about the craft of investing from my time working alongside my partners at @multicoin.
Eternally grateful for the opportunity to do this work in a culture defined by intellectual honesty, a deep respect for the founders we are fortunate to be partnered with, and the ambition to help reshape trillion-dollar markets.
Honored to step into this next chapter alongside my partner @SpencerApplebau
Tushar Jain@tushar_jain
I am excited to announce that @shayonsengupta and @SpencerApplebau have been promoted to General Partner and Co-Heads of Venture at Multicoin Capital. Over the past several years, both have taken on significantly more responsibility across every dimension of our business. They’ve not only continued to identify, source, and lead deals at an increasing rate, but have also increasingly taken on more ownership of the strategy, operations, and long-term direction of Multicoin. Multicoin was founded on the belief that crypto will fundamentally reshape global markets. We recently published our updated thesis for the next decade of crypto. We couldn't be more excited about the future of crypto and opportunity to invest in these theses.
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Excited to announce I am no longer unemployed!
Last June, I quit my job, emptied my apartment in San Francisco, and drove eight hours south to the suburbs of San Diego, where I moved into my friend Albert’s apartment.
For nine months, we lived on Tasty Bite Madras lentils and Shin ramen, working 10/10/7 from two desks in the living room, building an all-new clinical trial system-of-record from the ground up.
@runharbor is now providing electronic data capture for five different studies, ranging from internal feasibility to multisite and multinational — saving our customers weeks of database build time and hours of manual transcription effort.
Excited to finally launch publicly as part of @ycombinator's Spring 2026 batch — and if you’re a sponsor wondering why your clinical trial is taking so long, talk to us.
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as always the best thing for most people to do in markets is nothing
sid's writing has been quite thoughtful, rec checking it out
Sid⚡️@sidrmsh
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As oil crosses nearly $1B+ in traded volume on Hyperliquid, I made a real-time dashboard tracking WTI/Brent futures curves + volume/OI for traders.
Notably, summer month expiries spiked today. Markets are pricing in prolonged shortages.
Check it out:
oilfuturescurves.vercel.app
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tbh feels like a decent strat to just long hype anytime a major world event happens because people are gonna fomo in after seeing hip3 volumes
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Excited to announce that today is my first day at the @SolanaFndn working on growing the consumer ecosystem.
The mission is to accelerate Solana ecosystem teams to bring billions onchain. Grateful to continue the work I love: find exceptional people and help them turn their ideas into reality.
I have utmost conviction that Solana is and will continue to be the consumer chain, home of internet capital markets, and more. There's still so much work to do, we're still early, but even from glimpses so far it's clear: builders are here, momentum is real, and the best is ahead of us.
If you're building something interesting, DMs are open - let's chat!
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incredibly impressed with OpenAI Grove Cohort 2, looking forward to the next batch
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check out my paper w/ @SemiAnalysis_ !!!!!
SemiAnalysis@SemiAnalysis_
Are AI Datacenters increasing the electric bill of all American households? Power prices misconception, PJM's poor market design, Capacity prices 9.3x growth, ERCOT vs PJM gird reliability and expansion @TradeADMIS @ash_locked semianalysis.substack.com/p/are-ai-datac…
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@j0hnwang the weather doesn’t matter when you’re inside mission bro
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