medwireNews

Data analysis from ENSAT trial suggests effective hypercortisolism control is key to achieving favorable cardiovascular outcomes in patients with bilateral adrenal tumors, regardless of treatment modality @TheLancetEndo cushingshub.com/news/hypercort…

People with cyclic Cushing’s syndrome have a high risk for spontaneous adrenal insufficiency, delayed diagnosis, and inappropriate surgeries @TheLancetEndo cushingshub.com/news/study-hig…

Older women with a history of cervical cancer may benefit from screening for anal cancer, suggests research in @JAMANetworkOpen institut-servier.com/en/anal-cancer…

Measuring biochemical severity scores before adrenalectomy in people with mild autonomous cortisol secretion could help predict adrenal insufficiency, suggests research in @TheEndoSociety's JCEM cushingshub.com/news/biochemic…

Intensive blood pressure control strikes the right balance between cardiovascular disease and adverse events, including kidney-related events, suggests a study published in @TheLancet institut-servier.com/en/intensive-b…

Survivors of early invasive breast cancer have an increased risk of a second primary malignancy compared with women without a history of the disease, suggests research in @bmj_latest institut-servier.com/en/invasive-br…

Research indicates that targeted cancer therapies may be associated with a clinically relevant increase in the risk of arterial and venous thromboembolic events that varies with drug class and cancer type, as reported in @eClinicalMed institut-servier.com/en/targeted-ca…

Women who do not undergo surgery within 6 months of being diagnosed with ductal carcinoma in situ have an 11% increased risk of developing ipsilateral breast cancer over the following 8 years @bmj_latest institut-servier.com/en/invasive-br…

Artificial intelligence can speed assessment of tumour-infiltrating lymphocytes and immune phenotype identification in resected pancreatic cancer, research in @JAMASurgery demonstrates institut-servier.com/en/ai-analysis…

Paediatric hypertension is associated with a threefold increased long-term risk of major adverse kidney events, suggests research published in @LancetChildAdol institut-servier.com/en/childhood-h…

Low-dose olanzapine significantly protects against nausea and vomiting compared with placebo for women with breast cancer receiving anthracycline plus cyclophosphamide chemotherapy @TheLancetOncol institut-servier.com/en/low-dose-ol…

Adrenalectomy can help reduce hypertension in people with unilateral incidentalomas and mild autonomous cortisol secretion, suggest CHRIAC study findings in @TheLancetEndo cushingshub.com/news/minimally…

The neurokinin-targeted agent elinzanetant significantly improves vasomotor symptoms in women undergoing endocrine therapy for hormone receptor-positive breast cancer @NEJM institut-servier.com/en/elinzanetan…

Treatment with common psychiatric medications may be associated with an increased risk of amyotrophic lateral sclerosis, suggests a study published in @JAMANetworkOpen institut-servier.com/en/psychiatric…

The first randomised controlled trial of a CAR T-cell therapy in solid tumours has achieved a significant improvement in progression-free survival for advanced gastric and gastro-oesophageal junction cancer versus physician’s choice of therapy @TheLancet institut-servier.com/en/solid-tumou…

Risk-reducing surgery leads to improved overall survival for breast cancer patients carrying a BRCA1 or BRCA2 mutation, confirm two studies published in @TheLancetOncol institut-servier.com/en/mastectomy-…

Amiloride may be a suitable alternative to spironolactone as a fourth-line agent in patients with resistant hypertension, suggests a study in @JAMA institut-servier.com/en/support-for…

Childhood cancer survivors with severe-to-profound sensorineural hearing loss after chemotherapy or radiotherapy may be candidates for cochlear implants, US researchers report in @JAMAOnc institut-servier.com/en/childhood-c…

Patients with early-stage, deficient mismatch repair cancers may not require surgery after 6 months of neoadjuvant treatment with the PD-1 inhibitor dostarlimab, researchers report in @NEJM institut-servier.com/en/agnostic-dm…

Lorundrostat, a selective aldosterone synthase inhibitor, shows blood pressure-lowering potential in Advance-HTN trial participants with uncontrolled and treatment-resistant hypertension @NEJM institut-servier.com/en/lorundrosta…