Jamie Timmons

@agingroy You are completely correct. For two decades the largest science con I'm aware of, has brainwashed an entire generation of scientists working in exercise, metabolism & health. The originators of the defective & oft fabricated data, remain front & centre cell.com/cell-metabolis…

@KinglishMr @LibyaLiberty No tears, just pity.

@metapredict @LibyaLiberty mmmmh Jewish tears🥰

Same lies, no new evidence.

& so the cycle of crap nutrition science continues....

Who remembers this? Doctors surrounded by body bags, claiming that 500 people were killed at Al-Ahli Arab Hospital by the IDF, telling about how they were in the middle of surgery when the ceiling fell in and the hospital destroyed. Except none of it was true. And the hospital was still standing when the sun rose. The doctors in the press conference? Officials from Gaza's Health Ministry, which is part of Hamas. Independent sources soon verified Israeli claims that the damage was caused by a misfired rocket from Palestinian Islamic Jihad, and that it hit the parking lot of the hospital, not the hospital itself. Those same sources now estimate 50 or fewer people died, but nobody has ever been able to do an independent investigation of the site, Hamas will not let them. But ask anyone in Gaza, and they'll say that it happened just as Hamas claimed. It is a totalitarian society, and failing to toe the narrative of the party leads to horrific consequences not just for yourself, but for your family as well. It is remarkable the coordination of the lies and how many layers of lies there were around this incident. Why would anyone believe anything coming out of Gaza, particularly something that seems fairly incredible, without independent verification? Why do they want it to be true?

@MXHend Modesty & perspective assured 😂

We’re hiring a Postdoc in the Henderson Lab @ Van Andel Institute! Join our team studying neurodegenerative disease across scales (molecular → circuits). Flexible, high-impact projects and strong mentorship. Apply: vai.wd1.myworkdayjobs.com/en-US/VAICaree… Please share!

@HaithamElmasri1 Concrete & Tunnels. Terrorist Tunnels paid for by charity funds at the expense of their children & peace. You need help.

One of the most horrific crimes in history. Israel did not settle for destroying Gaza once; it returned to level its homes to the ground with tons of missiles and explosives, after having already destroyed them before. Israel left nothing standing; it turned Gaza into rubble and a desolate barren desert, devoid of any trace of life.

@implausibleblog lol. Yeh I don't pay my council tax until the leader of the council comes around and tells me.... Obviously keeping track of boats is harder that a house - but someone honest would enquire and then pay. Unless they are a dishonest cretin of course. Raynor Mark II.

There are ~200 berths at Lee Valley Marina Over 35 years, with normal turnover, that’s around 1,000 boats Dan Neidle revealed: only 1 ever registered for council tax Zack Polanski was one of the 999 who didn’t realise the rules applied. The council never chased anyone there. He’s now contacting them to sort any shortfall What was sold as “Zack Polanski dodging council tax” is actually a story about hundreds of boaters not understanding the rules, not paying, and a council not enforcing them A genuine mistake that’s being fixed So why has the media turned this into a full scandal suggesting he’s a tax avoider? This isn’t journalism — it’s a coordinated effort to tarnish Polanski over an error that 998 others at the same marina over 35 years also made Meanwhile, barely a peep about Nigel Farage’s £5m from his foreign crypto billionaire backer Double standards much?

@KinglishMr @LibyaLiberty Go back to your cave.

@LibyaLiberty Their God is the Devil, and they are his chosen people. Every accusation is a confession with these people...

@journeymanped @sh845274112872 @birchlse I think the term "cost effective" might be the clue to the intended ratio. 🤦‍♂️🤦‍♂️🤦‍♂️

@sh845274112872 @birchlse Princeton's per student endowment is ~$4million according to google. Are you suggesting that University of Sheffield only has 70 or so students?

UK universities are miraculous. A case in point is the University of Sheffield, which has a total endowment of £59m (about 21x Princeton's per-student endowment) and 6 Nobel prizes. We're losing one of the most cost-effective research juggernauts on Earth.

@KevinRhine_ @NatureCellBio Recent age - DN reg long gene length relationships is an artefact of RNAseq gene-length scaling issue. Using quantification methods not biased find opposite or distinct results. medrxiv.org/content/10.648…

Excited to share my lab's first paper -- a perspective piece in @NatureCellBio exploring how the mRNA lifecycle is affected by cellular aging! 🔬👴 nature.com/articles/s4155…

@BellaWallerstei Viking centre; no roses but well preserved.

We are visiting York for the first time this week and would love some suggestions (castles, museums, pubs and anything connected to Wars of the Roses!!) 😘😘

Apply Now to the Max Planck-Weizmann Joint Postdoctoral Program in the fields of: • Life Sciences • Chemistry • Physics • Earth Science • Math • Computer Science Includes a fully funded four-year position, split equally between the two institutions >>

The vasculature system as mapped by CODA. Color coded by radius size and Strahler order. We found that the vasculature for mouse, rhesus macaque, chicken, and turtle have the same scale-free space-filling fractal geometry (D = 3). Here: biorxiv.org/content/10.648…

@agingroy Unless dosing pharmacodynamically matched & the groups are extremely well matched (including for GLP1 related genetic influences) these trials are marketing bullshit. Let's be honest.

Sources and caveats (all links go to the actual papers): Weight loss head-to-head: SURMOUNT-5: Tirzepatide vs semaglutide, NEJM May 2025 doi.org/10.1056/NEJMoa… (Tirzepatide 20.2% vs semaglutide 13.7% at 72 weeks, n=751) Tirzepatide highest dose (SURMOUNT-1): 22.5%, NEJM 2022 doi.org/10.1056/NEJMoa… Semaglutide (STEP 1): 14.9%, NEJM 2021 doi.org/10.1056/NEJMoa… Retatrutide (triple agonist): 28.7% in Phase 3 TRIUMPH-3, Dec 2025 (Company data, not yet published in peer-reviewed journal. NDA filing expected late 2026.) 2. Heart attacks/strokes, SELECT: Lincoff et al., NEJM 2023 doi.org/10.1056/NEJMoa… 3. Blood sugar, SUSTAIN 1: Sorli et al., Lancet Diabetes Endocrinol 2017 doi.org/10.1016/S2213-… 4. Kidney, FLOW: Perkovic et al., NEJM 2024 doi.org/10.1056/NEJMoa… 5. Fatty liver, ESSENCE Phase 3: Loomba et al., NEJM 2025 doi.org/10.1056/NEJMoa… (FDA approved semaglutide for MASH with fibrosis August 2025) 6. Heart failure, STEP-HFpEF: Kosiborod et al., NEJM 2023 doi.org/10.1056/NEJMoa… 7. Sleep apnea, SURMOUNT-OSA: Malhotra et al., NEJM 2024 doi.org/10.1056/NEJMoa… (AHI reduction: 50.7% Trial 1, 58.7% Trial 2, per NEJM Table 2) What about Alzheimer's? Observational studies showed 40-70% lower risk, but Novo Nordisk tested semaglutide in two large RCTs (EVOKE, EVOKE+). Both failed. Program terminated Nov 2025. Not included because every item on this list has RCT-level evidence. What the tweet doesn't cover: - Common side effects: nausea, vomiting, diarrhea in 30-50% of patients - Muscle loss: you lose muscle alongside fat - Cost: $1,000+/month without insurance in the US - Retatrutide 28.7% is Phase 3 company data, not yet peer-reviewed - Benefits 2-6 tested with semaglutide specifically. Tirzepatide data for those conditions is still emerging.

Mounjaro beats Ozempic for weight loss. A head-to-head trial of 751 people proved it: 20.2% vs 13.7% at 72 weeks. And a triple-agonist in Phase 3 just hit 28.7%. But the weight loss isn't even the most interesting part. Here are 7 things these drugs do, ranked by strength of evidence: 1. Weight loss Mounjaro (tirzepatide): 20.2% in the head-to-head. Ozempic (semaglutide): 14.9%. A next-gen triple agonist (retatrutide) just hit 28.7% in Phase 3. 2. Heart attacks and strokes 20% fewer cardiovascular events in 17,604 people. The largest outcomes trial ever run on this drug class. (SELECT) 3. Blood sugar control 1.5-1.8 point drop in blood sugar markers, enough to get many people off daily insulin. Where the drug class started. (SUSTAIN, 8,000+ patients) 4. Kidney protection 24% fewer complications. This trial was stopped early because it worked so well they couldn't ethically keep giving placebos. (FLOW, 3,533 patients) 5. Fatty liver disease 37% of patients saw liver scarring reverse, vs 22% on placebo. Now FDA-approved for this. (ESSENCE, 800 patients analyzed) 6. Heart failure Patients could walk further, breathe easier, and reported much better quality of life. (STEP-HFpEF, 529 patients) 7. Sleep apnea 51-59% fewer breathing interruptions per hour. This used Mounjaro (tirzepatide), not Ozempic. (SURMOUNT-OSA, 469 patients) All 7 from randomized controlled trials. A weekly injection that started as a diabetes drug keeps passing tests nobody designed it for.

@Jay_Gallacher @RangersFC @JamTarts How do you open doors if you don't understand the difference between 2D & 3D? Are you amazed the door doesn't whack yer thick skull each morning?

Zack Polanski is not just the least intelligent person ever to lead a political party in the UK. He is also a chancer, a con-man and a fraud. The @TheGreenParty tying themselves to his mast to deflect from accusations of antisemitism would be laughable were it not so serious.

@doctoriaindarcy 🤡 "Tax lawyer Dan Neidle, founder of Tax Policy Associates, analysed Mr Polanski’s situation this week and wrote: “If the boat was in fact Mr Polanski’s ‘sole or main residence’ then he and/or his partner should have registered for, and paid, council tax for those three years.”

If Dan had researched this further, he would have found out that a lot of councils generally do not bill or enforced council tax on boat dwellers because if they did, they would have to offer he same amenities and the costs would far outweigh the money coming in.

@metapredict @RangersFC @JamTarts

Willie Collum and everyone that took part in this game all need to go their position is unattainable @RangersFC and @JamTarts need to apply pressure on them as decisions are deciding where the title can go

@MartyBowen11 I prefer that's he's just thick but another crook also works. You were right google clarified - absolutely is the same as a house if main residence - good job 👍🏻

@metapredict A houseboat on a mooring isn't the same as a house, chief, have a little Google. Maybe he does owe some in the end, but Niedle's half-arsed smear story doesn't try to find the evidence, besides asking the local laundrette how often they send their clothes. Desperate stuff.

So the story about Polanski dodging tax is actually wrong, and it's the council/marina who have messed up. Looks like a lot of folk living on those boats are getting an unexpected tax bill thanks to Dan. Labour are even pissing off the floating voters now lmao.

@MartyBowen11 Thanks 👍🏻 " ...the boat is your primary home, you are generally liable for Council Tax. The "Dwelling" Rule: Under UK law (specifically the Local Government Finance Act), a boat and its mooring together are treated as a "dwelling" if they are used as a sole or main residence"

@thelefttake @RightToBeMad 😂😂 No vaguely functional adult in the UK is unaware that they have to pay council tax at their primary residence He may have an argument for not knowing, given he's delusional and a wee bit thick.

@RightToBeMad If it was a deliberate act then sure, doesn’t seem like it was though.

Guys, nobody cares that Zack Polanski didn’t pay council tax on a boat he lived on from time to time. Nobody even knows you’re meant to pay council tax on a boat. Get a grip.