Sean Callahan, PhD

@willaise is an awesome scientist (and person and father!). Profound findings and lots to follow up on! Congrats! My fav finding: transplanting healthy immune cells reduces pathology in other diseased host cells. How does fixing ~10% of the brain help the other 90%?!

Thrilled to share our published @eLife paper "Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages" by 1st author Dr. @Marisa_Egan11 (@CAMBUpenn alum, now an Assistant Professor at @swarthmore Biology)! 🧵(1/n) elifesciences.org/articles/90107

📢 JOB ALERT: Tvardovskiy Lab at @PennEpiInst is hiring at all levels! Interested in chromatin biology, quantitative proteomics, or epigenetic modifications? Learn more about our research and apply at tvardovskiylab.org Please RT

The rebalancing of the immune system at the maternal-fetal interface ameliorates autism-like behavior in adult offspring. @CellReports cell.com/cell-reports/f…

@joeyzacks @ScienceMagazine @WeissmanLab @_alexafluor @MgAlameh @CHOP_Research Congrats!!

Delighted to share our work developing an mRNA vaccine for C. difficile, published today in @ScienceMagazine. This study with @WeissmanLab was co-led by two truly amazing scientists: @_alexafluor from the Zackular lab and @MgAlameh (now at @CHOP_Research)! science.org/doi/10.1126/sc…

@MedicineUVA @BradySpencer12 @NIH Congrats @BradySpencer12!! You’re a star!!

Congratulations to @BradySpencer12, PhD, assistant professor in the Dept. of Microbiology, Immunology, and Cancer Biology, for receiving a 2-year, $250,000 @NIH-NIAID Career Transition award to study streptococcus and its role in immune responses. bit.ly/47IjIaT

Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutieres Syndrome neuropathology biorxiv.org/cgi/content/sh… #biorxiv_neursci

Trainee Tuesday!! Join us every Tuesday to meet the rising stars in Neurotrauma research 💫 Introducing Mia Pacheco, an outstanding NNS trainee! Mia won the Michael Goldberger Award at the 2024 National Neurotrauma Symposium for her impactful contributions to spinal cord injury research. Mia also serves on the NNS Planning Committee, and volunteers with the NNS Local Scholars Program. Congratulations on your research and thank you for your service to the society! 🏆🧠 @mia_rayne @TAMUNeuro @TAMU_Biology

Congratulations to @efeierman (@korblab/ @PennNGG) & Katherine Alexander (@berger_lab/ @PennCDB), recipients of the 2024 Kaushal Family Awards in Genetics! A ceremony with presentations by the recipients will take place on 10/25 at 1pm in the CRB Austrian Auditorium @PennGenetics

Happy Birthday Ben! Today would’ve been his 70th birthday. A renowned scientist who changed the way we see glia cells and the brain and a wonderful friend and advocate, Ben was an inspiration to us all.  #neuroscience #glia #advocateforwomeninStem #TransRightsAreHumanRights

Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system: Immunity cell.com/immunity/fullt…

It's here! I'm recruiting a #postdoc to work with me on an ANR funded project @institutpasteur! Check it out! We're in @Chrom_Inf & @BCI_Pasteur

Biggest medical discoveries of the week (🧵) 1/10 Spinal cord injury triggers activation of T cells, inflammation, and death of neurons Editing the T cell receptor, using mRNA, suppressed this, and helped recovery from the injury (in mice!) (Paper: nature.com/articles/s4158…)

Excited to share our recent work on a GBS T7SS LXG toxin @alyx_job @KdoranLab —now out in mBio!🎉

Excited to announce the launch of the Center for Microbial Medicine @CHOP_Research! This new translational Center of Emphasis at CHOP will be dedicated to finding cures and improving pediatric health through the lens of the microbiome research.chop.edu/cornerstone-bl…

So excited to attend my first neuro and glia meeting! Can’t wait to learn all things glia and talk about my work with microglia epigenetics! #CSHLGlia

ONE SLEEP! #CSHLGlia @cshlmeetings

🎉🌟Andrea Anaya Sanchez @UCBerkeley won a FEBS Letters #PosterPrize at the #GordonResearchConference on #MicrobialToxins & Pathogenicity, recently held in Waterville Valley, New Hampshire, USA! 🏅Congratulations, Andrea! 👏👏👏 @GordonConf

🏅🌟We congratulate Nestor Ruiz @UTSWMedCenter, on winning a FEBS Letters #PosterPrize at the #GordonResearchConference on #MicrobialToxins & Pathogenicity, recently held in Waterville Valley, New Hampshire, USA! 🎉👏👏👏 @GordonConf @NestorRuiz2411

interested in knowing what glia cells will be discussed at #CSHLGlia @cshlmeetings next week? here is a breakdown \\ take homes: 1. astro, oligo, micro make up most of the community 2. we pushed hard to have extra peripheral glia in the oral presentations 3. 5 SLEEPS!