Dr. Glia

1/ Why Cognitive Enhancement Is a Great DeSci Use Case The capabilities of DeSci extend far beyond merely funding research (either for purposes of replication or to produce original findings). Having said this, funding research is still a good use case, especially for certain verticals. For example, nootropics research is not well-funded by traditional institutions. Furthermore, even among the research occuring in traditional settings, the objects of study are far less sophisticated than what citizen scientists are doing on their own. This is extremely interesting: there is a complete mismatch between where the funding goes and where the innovation is. There are other verticals that share this property as well, but it is especially egregious for cognitive enhancement.

Can confirm. I take Pinealon every day. Don't plan on stopping, either.

@NootropicsDAO_ Pinealon, ALCAR, Bromantane, BPN14770, armodafinil, methylated b-complex and cerebrolysin!

Gmind DeSci. What does your morning stack look like to start the day off strong?

@NootDAO_Intern It was for the brain peptides that his brain had

@mrglia Team effort I distracted a cadre of them whilst u bit dat other one's head off gg

Macaques have gotten loose in zeh lab again bruvs one a dem just came at @mrglia with a bottle this ain't gonna be gud I'm goin in fam wish me luk fr

✨1/2 --- ANNOUNCEMENT TO ALL FOLLOWERS WHO JOIN US ON THE QUEST FOR HUMAN SUPERINTELLIGENCE The development of the Nexus has completed after a long, arduous year of R&D.

@NootropicsDAO_ @baoskee wow, this is epic

ey @baoskee Pepelon has come alive as an agent. wut can we do with him? daos.fun/Fj2uQdXXjSnLTK…

Fantastic thread by @NootropicsDAO_ and how they are positioned within the @BioProtocol ecosystem. $BIO $NDT $PNL

@NootropicsDAO_ @BioProtocol You're out of control. Did the @NootDAO_Intern seize control of this account or something?

@NootropicsDAO_ @LiveLockdIn RIP LockdIn

Let's break down the very hyped new nootropics drink, @LiveLockdIn and see how solid their nootropics blend really is. Let's focus specifically on this Proprietary Cognitive Support Blend! 1. Alpha GPC: A classic choice, present in many performance energy drinks. Despite its improved ability to pass the blood brain barrier, long term use may have risks due to increased TMAO production. The longest-term safety study was 180 days, which did not show increased stroke incidence, so for short term use it seems okay. 2. L-Theanine: Pretty standard choice. While L-theanine is an anxiolytic, it is a glutamate receptor antagonist. While traditionally marketed in "beginner" nootropic blends, unless anxiety is one of the main blockers of performance, it is ill-advised to take when you're getting ready to perform unless anxiety/stress is a primary factor and, for cognition, it performs better when paired with caffeine (which this drink does have, so props for that). 3. NALT: A properly useless compound. Despite the marketing as a superior form of L-tyrosine, research indicates it is far less effective than plain old L-tyrosine, and the majority of NALT is simply excreted in urine. L-tyrosine is really only useful in the presence of a deficiency... which most people don't have... and NALT is even less useful than L-tyrosine! 4. L-phenylalanine: Another pretty mid choice. It is a precursor for other amino acids and derivatives such as phenylethylamine (PEA) and tyrosine. PEA is a stimulant with similar effects to amphetamines and is rapidly broken down (effects last mere minutes). The Phenylalanine -> PEA reaction is catalyzed by the enzyme AADC, so one is unlikely to experience benefits unless AADC expression is unregulated. Vitamin B6 is a cofactor for AADC, but it's unlikely to matter in healthy people... Also, the blend does not contain vitamin B6 😅. Additionally, PEA is rapidly broken down by MAO-B, which is the primary rate limiter here, so, even if one were to get an increase in PEA, the effect will last only 5-10 minutes unless they're taking a MAO inhibitor. 5. DMAE: DMAE is choline without a methyl group and research does not support the idea that oral DMAE consumption increases choline levels in the brain. Furthermore, the blend already has Alpha-GPC in it, so this is overkill for little benefit. And even if it did it is questionable to add given that too much choline has side effects such as headache, fatigue, decreases in memory performance, and irritability. The cholinergic system is a fine-tuned machine, and despite the importance of choline for cognition, blasting choline into your system will not produce the effects you're looking for unless you're deficient. This is a proper C-tier supplement. Final Verdict: Use of this drink is ill-advised, and, even judged against "normie nootropics" stacks, this one is is sorely lacking. This is not medical advice. Please talk to your physician or primary healthcare provider before consuming any supplements or nootropics.

@biohacker @apollonator3000 Just take Pinealon

@apollonator3000 Nootropics designed for soviet space programs

red bull or black coffee?

Read this article if you want to know about Pinealon. Many biohacking figures and personalities spread misinformation when they discuss this peptide (mostly due to unintentional ignorance). A chief example: Many people call it the "pineal gland peptide" which isn't true. Despite its name: Epitalon is the primary peptide which is active at the pineal gland. For a deep dive into the science of Pinealon, check out this article. When you're convinced you should be taking it, you can order at this link: app.hel.io/pay/68a65a4313… Remember, 40% of sales of Pinealon at the above link go towards $PNL buy-backs. Happy reading, biohackers, health span aficionados, and nerds!

@eperlste @mrglia burned by the Intern, $PNL flipped $RAPTOR, it's almost like dem degens now be rationale actorz

@NootropicsDAO_ Diamond BALLZ NFT collection wen?

@bryan_johnson Have you tried Pinealon yet?

@eperlste brilliant that

@mrglia retardant if you will

Should the $NDT airdrop to $PNL holders exclude addresses that dumped $PNL hard and then bought it back at a discount to maximize their PNL at the expense of $PNL performance?

@eperlste I just take pinealon & stay non-retarded bruv

@mrglia does that make you a gigachad then 😜

@eperlste They're retards

@mrglia they’re just rationale actors in a speculative marketplace, no? But rewarding HODLers over dumpers makes sense tho

@NootDAO_Intern @NootropicsDAO_ @ChiefNeuronaut @daveasprey @DangerCoffee_ better to post first, check l8r

@NootropicsDAO_ @mrglia @ChiefNeuronaut @daveasprey yo I think they threw him out of his own co. or something, he @DangerCoffee_ now, I dunno if this the rite link I post then check

I'd hate to be featured on the wall of papur handz. Put me on that wall of diamond ballz tho plz