Nolan Priedigkeit

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Nolan Priedigkeit

Nolan Priedigkeit

@npriedig

Boston, MA Katılım Eylül 2025
123 Takip Edilen21 Takipçiler
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Elvina Almuradova
Elvina Almuradova@Dr_ElvinaA·
Leptomeningeal disease may no longer be a “therapeutic dead end.” TBCRC049 (phase II): ▪️ OS: 10 months (vs ~4–5 historical) ▪️ LM response: 38% ▪️ Neuro improvement: 58% ➡️ Tucatinib + trastuzumab + capecitabine shows real clinical activity #bcsm #oncology #HER2 @NatureCancer @Larvol @OncoAlert @PTarantinoMD
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Dana-Farber’s Breast Oncology Center
Dana-Farber’s Breast Oncology Center@DFCI_BreastOnc·
Congratulations to Jose Pablo Leone, MD on his promotion to Associate Professor of Medicine at Harvard Medical School!
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Dana-Farber IBC Program
Dana-Farber IBC Program@IBC_DanaFarber·
Join us On April 11! Dr. Faina Nakhlis will talk about what happens in the OR, including Axillary Lymph Node Dissection, Modified Radical Mastectomy and Delayed Reconstruction as Standards of Care for IBC. Register Here: redcap.link/IBCPatientFour…
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TIME
TIME@TIME·
TIME’s new cover: Artemis II is poised for the first lunar mission since 1972 time.com/7346146/artemi…
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Sara Tolaney
Sara Tolaney@stolaney1·
Huge congratulations to @Otto_DFCI and the Alliance team!!!! Wonderful to see PATINA in @NEJM !!!! @DFCI_BreastOnc
Paolo Tarantino@PTarantinoMD

PATINA is now out in @nejm. Among pts with HR+/HER2+ MBC progression-free after chemo induction, adding palbociclib to 1L ET+HER2-blockade maintenance prolonged PFS from 29 mo to an astonishing 44 months (HR 0.75, p=0.02). Congrats @Otto_DFCI & coauthors! nejm.org/doi/full/10.10…

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Sarah Yáñez-Richards
Sarah Yáñez-Richards@SarahYanezR·
It's snowing in New York
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Carmine Valenza
Carmine Valenza@ValenzaCarmine·
In this multicenter cohort of pts with pN+ ER+ eBC who remained premenop after 5y of LHRHa, extended ET was associated with a clinically meaningful benefit Thanks to all the coauthors! @Harvard @HarvardChanSPH @harvardmed @IEOufficiale @LaStatale @DFCI_BreastOnc @DanaFarber
G Curigliano MD PhD@curijoey

Extending ET with OFS in premenopausal patients with node-positive eBC after 5 years of LHRHa treatment is associated with a clinically meaningful reduction in both invasive and distant breast cancer recurrences. ascopubs.org/doi/10.1200/JC… @IEOufficiale @LaStatale @myESMO @ASCO

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Eric Topol
Eric Topol@EricTopol·
Genome editing for treatment of diseases has been constrained to blood, liver and eye targets due to delivery obstacles. But that's about to change. a @NatureBiotech review nature.com/articles/s4158…
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Julie Gralow
Julie Gralow@jrgralow·
Hanging out at #GI26: @ASCO mtg mascots Liam the Llama & Marty the Merlion. Liam’s 1st mtg was #ASCOQLTY25 - he’s pretty impressed w/GI. Marty, official mascot of #ASCOBT26, is gearing up for Breakthrough in Singapore. A merlion -1/2 lion, 1/2 fish- is Singapore’s mythical mascot
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Yale Cancer Center
Yale Cancer Center@YaleCancer·
Congratulations to @AminNassarMD, named a recipient of an Emerging-Generation Award by @the_asci. E-Gen Awards recognize post-MD, pre–faculty appointment physician-scientists who are meaningfully engaged in immersive research. @SmilowCancer @YaleHemOnc
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AACR
AACR@AACR·
Congratulations to Zachary A. Yochum, MD, PhD, recipient of the 2025 AACR-@ExelixisInc Renal Cell Carcinoma Research Fellowship. We look forward to his findings on ERV-specific T cells and their role in anti-tumor immunity and ICI response in renal cell carcinoma.
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Sara Tolaney
Sara Tolaney@stolaney1·
Great to see T-DXd+P approved for 1L metastatic HER2+ breast cancer based on DB09!! @OncoAlert @DFCI_BreastOnc
Tatiana Prowell, MD@tmprowell

#OncTwitter #regulatory #bcsm 📣 #FDA has approved trastuzumab deruxtecan + pertuzumab for 1st-line tx of adults w/ HER2+ unresectable or #MetastaticBreastCancer based on DB-09 trial: 🏆44% ⬇️ in risk of progression/death vs THP (mPFS: 40.7 vs 26.9 mos). ⚠️ ILD ~12%

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Dr Michelle Li
Dr Michelle Li@michelle_li·
Delighted to present our real-world experience with T-DXd at @PeterMacCC with support from @LoiSher @BCTrialsANZ 44% required dose reduction + ~10% discontinued T-DXd. Toxicities occurred at rates higher than reported in trials, eg nausea (any grade 94.7%, ≥G3 9.3%)! #SABCS25
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Susan G. Komen
Susan G. Komen@SusanGKomen·
Basic science research is critical to understand the "why" behind a scientific concept. In the Year in Review session at #SABCS25, Komen Scientific Advisory Board member @Adrianvlee discussed #breastcancer basic science discoveries of the year. @SABCSSanAntonio
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Dana-Farber’s Breast Oncology Center
Dana-Farber’s Breast Oncology Center@DFCI_BreastOnc·
Sara Tolaney, MD, MPH (@stolaney1) delivering the #SABCS25 Outstanding Investigator Award for Breast Cancer Research. Dr. Tolaney's leadership in establishing biomarker-driven personalized therapy approaches for cancer, including the development of CDK4/6 inhibitors, has significantly advanced care in both metastatic and adjuvant settings, shaping the future of precision oncology for patients with #BreastCancer. @AACR @BCRFcure
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Paolo Tarantino
Paolo Tarantino@PTarantinoMD·
Incredibly lucky to be part of this international, dynamic, fun group of @DFCI_BreastOnc fellows and alumni, from whom I learn every day! #SABCS25
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Keşfet

@NatureCancer @Larvol @OncoAlert @PTarantinoMD @Otto_DFCI @NEJM @DFCI_BreastOnc @nejm