ok
83 posts


@sokrypton I think TMalign actually does find those similarities. It’s undocumented, but worked for me on a real example. Will certainly check out the domains from the paper for my lecture next week on protein structure comparison!
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🚨 For those training DL models on proteins, it's possible your "structural" train/test split might have leakage cus tools like foldseek/TMalign (and CATH/SCOP databases) do not always account for structural relationship of circularly permuted proteins:
Aiden Kolodziej@aidenosinetrip1
Excited to share my recent work, CIRPIN 🐍 with @sokrypton and @MazAbulnaga on the discovery of thousands of naturally occurring circularly permuted protein domains
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I am pleased to announce that our latest work on comparative metagenomic analysis of COPD and health control samples has been published today: doi.org/10.3389/fmicb.…. This marks a meaningful milestone in my PhD.
Deep thanks to my supervisors @ok55991 and Prof.Dr.Dr Robert Bals.
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What an exciting week it's been at the #ISMBECCB2025 conference! The Drug Bioinformatics group had a fantastic presence, with six members presenting their latest work across various COSIs.
linkedin.com/feed/update/ur…
@nosirrag9 @AnastasiaK15988 @amay_agrawal @JeSuisAlper @ok55991
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DataSAIL's "press tour" stops @MlcsbC @ISMBinfo in Liverpool for a talk and a poster. If you're in ML, come around and check the data splitting out.
I'm looking forward to this and the keynotes by the Nobel Laureates John Jumper and David Baker!
@ok55991 @dbblumenthal
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@not_a_reptiloid Не стоит. Желтый пакет - это не recyclable мусор, это обычный мусор, только бесплатный. А на мытье ты больше воды и мыла потратишь
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@LindorffLarsen @BBKrage I am starting to teach my structural bioinformatics course next week, and I have an idea for an excellent opening slide :D
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Excellent planning by @BBKrage on our BSc level Protein Science course
Yesterday I was teaching protein structure prediction and tomorrow we will discuss protein design
Maybe I should add a new slide




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A Perspective from @itisalist @judith_bernett @RomanJoeres @ok55991 @FloHasee @dg_grimm @bit_tumcs & @dbblumenthal discusses the issue of data leakage in machine learning models and presents 7 questions to identify and avoid problems as a result. nature.com/articles/s4159…

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@not_a_reptiloid Или между гравелом и гравелом) Приезжай, их есть у меня, хотя шоссер старенький
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@not_a_reptiloid Между чем и чем? Между разными великами или между контактами и нет? В обоих случаях - да, чувствую, но я не молодой спортивный мужик
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@not_a_reptiloid Могу одолжить шоссер - мне кажется, ты по росту подойдешь. Оценишь разницу)
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