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🆕Our latest research @JAMA_current @JAMACardio:
🔎 objective biomarkers of #frailty in older adults undergoing #TAVR:
🥇 - The combined phenotype of osteosarcopenia
⬇️🦴 & ⬇️🥩 (D) was found to be associated with:
a) ⬆️3⃣-fold increase in post-TAVR mortality ✅
b) ⬆️2⃣-fold increase in incident disability ✅
🥈 Isolated findings of
low bone density ⬇️ 🦴 (B) or
low muscle mass ⬇️ 🥩 (C)
were not associated with mortality ❌ or incident disability ❌.
🥉 Opportunistic assessment of muscle mass and bone density is readily feasible from CT scans acquired for routine TAVR planning.
No extra testing!
@FrailtyMD
➡️ Future: developing of deep learning models #AI
coreslicer.com
@mcgillu @FINBAsturias @semeg_es
JAMA Cardiology@JAMACardio
Osteosarcopenia, as assessed by CT, is a novel geriatric risk factor that can be opportunistically measured prior to TAVR to inform decision-making and identify patients who may benefit from rehabilitation interventions. ja.ma/4dJHbes
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