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Kari Hoffman
1.1K posts
Kari Hoffman
@perpl_lab
PI at Vanderbilt University. See @[email protected]
Nashville, TN Katılım Mart 2015
274 Takip Edilen690 Takipçiler
Kari Hoffman retweetledi
2/2 Abilities of inhibitory control, WM updating, and shifting distinguished cognitive phenotypes in NHP's; expl. factor analysis suggested 1) WM updating 2) Shifting/Learning, and 3+4) inhibitory control of interference from external vs internal sources are 4 sep. cogn. factors.
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Kari Hoffman retweetledi
New paper shows causal effects of gaze-contingent stimulation on learning feature-based attention: Treuting et al. (2025) Adaptive Reinforcement Learning is causally supported by Anterior Cingulate Cortex and Striatum. Neuron cell.com/neuron/fulltex…
1/2
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Kari Hoffman retweetledi
Experience reorganizes content-specific memory traces in macaques 🐒🧠. @perpl_lab @AymanAljishi
tinyurl.com/Perpllab-react
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Kari Hoffman retweetledi
🌟 Cai Lab @Nature paper alert! In new work led by @mysteriousjoe_, we find that rest periods after learning not only stabilize new memories BUT ALSO integrate new memories with older ones from days past! (1/9)
Read it here: nature.com/articles/s4158…
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Kari Hoffman retweetledi
I am and have been fascinated with how memories are formed and stored. A big challenge, not unique to memory, is synthesizing concepts across scales of anaylsis - from molecules to computation. Here I try to distill how we can move forward in understanding memories. Thanks /1
The Transmitter@_TheTransmitter
Jason Shepherd @JasonSynaptic asks eight scientists to weigh in on what makes memories last—dynamic ensembles or static synapses? thetransmitter.org/the-big-pictur…
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@Timothy0Leary “Silent” residual Ca++ and WM. Counterintuitive to some, and still not fully embraced in chunks of the literature: science.org/doi/10.1126/sc…
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what are your top 1-3 computational neuroscience papers that told you something counterintuitive about the brain?
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What makes memories last—dynamic ensembles or static synapses? | The Transmitter: Neuroscience News and… disq.us/t/4r3afea Thanks to @JasonSynaptic for organizing!
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Come to U10 U11 this morning if you’re interested in NHP cell assemblies, memory replay, wireless recording 100s of units during learning of new and old context-specific sequences, all in freely moving (and sleeping) monkeys #sfn2024
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Kari Hoffman retweetledi
Kari Hoffman retweetledi
New research from @perpl_lab sheds light on the circuit organization that supports memory and spatial cognition. 🧠 This discovery helps with our understanding of how our brains process complex cognitive tasks.
🔗 Read the full study here 👉
cell.com/cell-reports/f…
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Kari Hoffman retweetledi
New Paper in @CurrentBiology! Chimpanzees across FIVE communities take rapid turns in gesture-to-gesture exchanges resembling human conversational patterns. Language may not be a pre-requisite for fast-paced, coordinated communication in social species sciencedirect.com/science/articl…
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Kari Hoffman retweetledi
Women are consistently under-cited in neuroscience. @anne_churchlandand and @FDavatolhagh share tools that can help assess citation diversity.
thetransmitter.org/publishing/wom…
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Kari Hoffman retweetledi
Cortical interneurons learn on the job! Speculated this was true a decade ago! @JJSherryWU and @artofbiology finally provide evidence! biorxiv.org/content/10.110…
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@GeorgeDragoi2 @markbrandonlab @NatureNeuro @YalePsych @YaleNeuro @WuTsaiYale @YaleMed @kefei_6 This looks amazing - congratulations!
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Most knowledge of sequence p/replay comes from single experiences. Now we reveal principles of generative coding enabling HPC to parallelize & bind time-compressed representations of 15 discontinuous experiences in single events in sleep @NatureNeuro: rdcu.be/dOjCv 1/6
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Kari Hoffman retweetledi
Monumental new work from the @GeorgeDragoi2 lab tackles the question of how replay can parallelize, bind, and compress representations of 15 (!) unique linear track experiences: nature.com/articles/s4159…
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@perpl_lab @SAbbaspoor @CellReports @DiagBiochips Nice work! Interested in hearing more about the DA probes!
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📢The latest from talented @SAbbaspoor 's PhD is out in @cellreports! You into ensembles (@DiagBiochips DA or #neuropixels in #nhp)? ❤️CA1 microcircuits? Wonder why we don’t know how they support #memory or behavior in #primates? Like inhibitory cell types? Cell Assemblies in😴?
Saman Abbaspoor@SAbbaspoor
Excited to share that the latest @perpl_lab paper is published in @CellReports. We describe the dynamics of superficial and deep CA1 pyramidal cells and identified putative groups of inhibitory cells in freely moving, thinking, and sleeping macaques. 1/n
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@okaysteve Downloaded! I may start at the end b/c this chapter from @TJRyan_77 looks especially promising:
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