Pranitha Vangala

No pandemic can stop me from celebrating this wonderful moment with @garber_manuel @GarberLab @GSBS_UMassMed @UmassMedbioinfo. Best thing is Manuel smiling in his regalia #UMassMedical20 👩‍🎓🎓

Discover the latest advancements in vitiligo research! Learn how the VIGOR project at UMass Chan Medical School is unraveling the complexities of this autoimmune condition. Join the conversation and explore how AI and data science are transforming our understanding and treatment of vitiligo using Via Foundry. #VitiligoResearch #AutoimmuneDiseases #MedicalInnovation #UMassChan #VIGORProject Read more here: medium.com/viascientificp…

We’re excited to announce that ViaScientific’s advanced technology now enables the Adaptive Immune Receptor Repertoire research group to effortlessly share reproducible pipelines with the scientific community. #reproducibility #empoweringscientists #bioinformatics #bigdata medium.com/viascientificp…

@bloodgenes @harvardmed @DanaFarber @BostonChildrens @broadinstitute Congratulations @bloodgenes

20 years ago I was finishing my first year at @harvardmed... Never did I imagine I would be here today. Grateful to all the incredible lab members past and present, amazing mentors, remarkable colleagues, and others who have made this possible! 🙏 for all those who wrote letters!

Congratulations Phillip Zamore of @UMassChan, newly inducted #NASmember! #NAS161 #genetics #medicine

@mithunmittir @DuttaShuvadip @ranjithpa That’s right many E-P loops don’t change even when the TADs are disrupted. So that’s why I was wondering if TADs provided that optimal space, disruption has little to no impact.

@mithunmittir @DuttaShuvadip @ranjithpa When TADs are dustrupted in CTCF Degron models, several groups showed minimal disruption of transcription. How does you model explain that ?

Our latest paper to wrap up the year. We propose that intersegmental jumps that leverage looped conformations of chromatin can lead to efficient search. Read the preprint at: biorxiv.org/content/10.110… Led by @DuttaShuvadip & Adarshkrishnan. Fantastic collab. with @ranjithpa (1/4)

@ranjithpa @mithunmittir @DuttaShuvadip Interesting, I have to think to see if any literature has a time course of expression captured with CTCF degron. Thank you !

@pranithakrishna @mithunmittir @DuttaShuvadip I see it in the following way: our model predicts that disruption of the TAD structure would make target-finding sub-optimal but not impossible. Naively extrapolating it to gene expression would imply that gene expression is possible, but the kinetics of expression could change.

@mitchguttman Can’t wait to read it! I have been waiting for it since Manuel told me about it!

Gene expression involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. We developed ChIP-DIP – a method for simultaneous, genome-wide mapping of hundreds of DNA-protein interactions in a single experiment. biorxiv.org/content/10.110…

@garber_manuel Still can’t get over the news. RIP Patrick. So many memories with you in Garber Lab

I want to take a moment to remember Patrick McDonel who passed yesterday. I owe much of the fun things I do in science to Patrick McDonel. He taught me to think about molecular biology and instilled the ethos of my lab. Join mein keeping his memory.

@anshulkundaje summaries what’s going on many minds. This is a horrible reality we all will see.

Despite modernisation, economic growth and rising proportions of employed women in the twentieth century, for a long period of time the earnings gap between women and men hardly closed. According to 2023 economic sciences laureate Claudia Goldin, part of the explanation is that educational decisions, which impact a lifetime of career opportunities, are made at a relatively young age. If the expectations of young women are formed by the experiences of previous generations – for instance, their mothers, who did not go back to work until the children had grown up – then development will be slow. #NobelPrize

Historically, much of the gender gap in earnings could be explained by differences in education and occupational choices. However, this year’s economic sciences laureate Claudia Goldin has shown that the bulk of this earnings difference is now between men and women in the same occupation, and that it largely arises with the birth of the first child. #NobelPrize

@_prashantbhat @Caltech @mitchguttman @uclacaltechmstp Congratulations 🎉

🎓Defended my PhD thesis @Caltech this week! Grateful to my incredible advisor @mitchguttman, the @uclacaltechmstp, and the countless individuals who brightened my years in graduate school into a delightful experience of intellectual growth and discovery. Cheers to science! 🧬

We are looking for passionate and creative Full Stack Developers and Bioinformaticians. Please spread the word to help us to find people with Comp./machine learning analysis capabilities to create an ecosystem to help scientists worldwide #fullstackdeveloper #bioinformatician

Wow! We had the solution for preventing COVID deaths all along. Will just add that you should also avoid aging & definitely stop doing silly things like getting immuno-compromised. Also forgot to mention the one thing that actually does prevent severe outcomes - take the vaccine

@elonmusk You delivered 310k new cars but somehow don’t care about existing customers. Not able to drive my Tesla due to broken windshield for the last 6 months. You say global glass shortage but have the glass for ur new cars. #Tesla #ElonMusk

@AouadiLab @DiabetesLUDC @VforVaz @Ceci_Morgantini @EmelieBarreby @laulevi84 @AchilleasFar @Ana_Vankova @_madbri @LeaDC_Naudet @7ohanssonAlex Congratulations

@ProgMolMed @nephantes @RogerJDavis1 @GSBS_UMassMed @UMassMedical Congratulations @nephantes !!

Congratulations to Alper Kucukural PhD - recipient of the 2021 GSBS Faculty Award!! tinyurl.com/f2wf8br8 @nephantes @RogerJDavis1 @GSBS_UMassMed @UMassMedical

@UMassMedical @theNASciences @FitzgeraldKate @UMassMedRTI Congratulations @FitzgeraldKate !!

Congrats to @UMassMedical's newest inductees into the National Academy of Sciences! Katherine Fitzgerald, PhD, is an international leader in the field of innate immunity, and Nikolaus Grigorieff, PhD, is a cryo-EM pioneer. #NAS158 @theNASciences @FitzgeraldKate @UMassMedRTI

This is just fantastic!!