Saurabh Patel 💊🏏🏀📑

@TradingThomas3 Deadline to extend the deadline is Monday night!

Deadline is Monday night.

@PensareBBall Ummm, love Scottie as PG and he should be full time PG. Make roster moves around Scottie as PG. Dump Poetl and Quickley off season and get Nixton and Simmons off season. Also on this play 1 vs 4 which just shows how dangerous Scottie is in the paint!

Point Scottie. "everybody eats"

@TrendSpider You can have 100 different technical analysis! Look at Wyckoff and you will see shake out and accumulation starting. Look at Elliott Wave theory and you see wave 4 forming! Both are extremely bullish. What matters is SoFi is delivering+ve results! Charts will catch up!

Down 39.5% YTD and insiders are trying to catch the falling knife 🔴🔪 $SOFI

@BradSpellberg @ABsteward @DrToddLee I wish we had PCT and most hospitals in Toronto areas don't use PCT to stop abx. Last time I checked with the lab it was about $100 per test which didn't make sense from $$. Thanks for the input.

@sarubactam @ABsteward @DrToddLee 5) Thank you procalcitonin and Biofire. if I get a virus back and procal low, Im stopping.

Time to revisit empiric atypical coverage in non-severe CAP? 🆕⚡🔴Target trial emulation using a propensity-weighted cohort from 68 hospitals in Michigan >66,000 patients: • No difference in time to clinical stability • No difference in ICU transfer or antibiotic duration • No difference in 30-day mortality • But ↓ composite 30-day mortality/rehospitalization with azithromycin Signal… or bias?” academic.oup.com/cid/article-ab…

@BradSpellberg @ABsteward @DrToddLee How do you do that empirically? We struggle as there are RCTs to use and not use macrolides with BL. We have no idea what is our atypical rate is and many "CAP" are either viral, no pathogen isolated.

@ABsteward @DrToddLee I wish people would stop with this “target trial emulation” business. You did a retrospective observational study with propensity matching. Period. Be honest & call it that. Result won’t affect my practice. If atypical pna possible give azithro. If it’s a typical pathogen, don’t.

@DrJStrategy agree! Canada has already met the 2% NATO spending in a year, something we thought would take a decade! Trump lit a fire. However, there are consequences to his actions. Allies will decouple from the USA. It will no longer be able to call shots & may be that is what it wants

Food for thought. Trump, Hormuz and the End of the Free Ride For half a century, Western strategists have known that the Strait of Hormuz is the acute point where energy, sea power and political will intersect. That knowledge is not in dispute. What is new in this war with Iran is that the United States, under Donald Trump, has chosen not to rush to “solve” the problem. In Hegelian terms, he is refusing an easy synthesis in order to force the underlying contradiction to the surface. The old thesis was simple: the US guarantees open sea lanes in the Gulf, and everyone else structures their economies and politics around that free insurance. Europe and the UK embraced ambitious green policies, ran down hard‑power capabilities and lectured Washington on multilateral virtue, secure in the assumption that American carriers would always appear off Hormuz. The political class behaved as if the American security guarantee were a law of nature, not a contingent choice. Their conduct today is closer to Chamberlain than Churchill: temporising, issuing statements, hoping the storm will pass without a fundamental reordering of their responsibilities. Trump’s antithesis is to withhold the automatic guarantee at the moment of maximum stress. Militarily, the US can break Iran’s residual ability to contest the Strait; that is not the binding constraint. The point is to delay that act. By allowing a closure or semi‑closure to bite, Trump ensures that the immediate pain is concentrated in exactly the jurisdictions that have most conspicuously free‑ridden on US power: the EU and the UK. Their industries, consumers and energy‑transition assumptions are exposed. In that context, his reported blunt message to European and British leaders, you need the oil out of the Strait more than we do; why don’t you go and take it? Is not a throwaway line. It is the verbalisation of the antithesis. It openly reverses the traditional presumption that America will carry the burden while its allies emote from the sidelines. In this dialectic, the prize is not simply the reopening of a chokepoint. The prize is a reordered system in which the United States effectively arbitrages and controls the global flow of oil. A world in which US‑aligned production in the Americas plus a discretionary capability to secure,or not secure, Hormuz places Washington at the centre of the hydrocarbon chessboard. For that strategic end, a rapid restoration of the old status quo would be counterproductive. A quick, surgical “fix” of Hormuz would short‑circuit the dialectic. If Trump rapidly crushed Iran’s remaining coastal capabilities, swept the mines and escorted tankers back through the Strait, Europe and the UK would heave a sigh of relief and return to business as usual: underfunded militaries, maximalist green posturing and performative disdain for US power, all underwritten by that same power. The contradiction between their dependence and their posture would remain latent. By declining to supply the synthesis on demand, and by explicitly telling London and Brussels to “go and take it” themselves, Trump forces a reckoning. European and British leaders must confront the fact that their energy systems, their industrial bases and their geopolitical sermons all rest on an American hard‑power foundation they neither finance nor politically respect. The longer the contradiction is allowed to unfold, the stronger the eventual synthesis can be: a new order in which access to secure flows, Hormuz, Venezuela and beyond, is explicitly conditional on real contributions, not assumed as a right. In that sense, the delay in “taking” the Strait, and the challenge issued to US allies to do it themselves, is not indecision. It is the negative moment Hegel insisted was necessary for history to move. Only by withholding the old guarantee, and by saying so out loud to those who depended on it, can Trump hope to end the free ride.

@DrJStrategy We will find out in 2-3 weeks who got it right and who got it wrong. However, an incoherent and rambling messaging doesn't help and that is what the market is reacting to, the uncertainty!

Food for thought. Markets again misread Trump’s Iran speech by taking him literally, not seriously. His “Stone Age” threats are leverage, not a base‑case plan. If credit markets truly believed him, the 10‑year Treasury yield would be well north of 4.5%; it sits closer to 4.37%. Objectives have essentially been achieved, so given the TDS saturating Wall Street and the media, last night’s emotional overreaction should surprise no one.

@RaptorsShaq if you look at the entire season, Darko is always a step behind, wrong substitutions and combination on the floor! Shead is great at defense but bad at offense! You see glimpses of great basketball but mostly inconsistency. No hunger to compete except for Scottie/CMB/Jakobe...

Fire Darko Fire Bobby Trade literally everyone zero excuse dropping a must win game at home against the worst team in the league

@hamids @garyblack00 A great point! Honestly, after seeing what Elon has done with Tesla and X, not too keen on jumping at IPO...happy to see the results before investing.

@garyblack00 Any fund manager who thinks sitting out of a single stock is “too risky” should not be a fund manager. No investor should be thinking they have to make money on everything!

SpaceX's IPO is expected to create intense pressure on professional investors to participate, even at a valuation north of $1T, simply because sitting out may be too risky, The Information's reports. That urgency has only grown after Nasdaq approved rule changes allowing very large companies to join its major index just 15 days after listing, which is far sooner than the previous three month wait and float requirements. Fund managers fret that if they sit out the SpaceX offering and the shares soar, their performance will look dismal. Musk and his bankers are well aware of the buying pressure they're putting on fund managers, with a record $75B worth of stock to sell. $TSLA theinformation.com/briefings/nasd…

@AverageDipBuyer @anthonynoto @Dboybruh @elonmusk This is an insult to Noto, sorry!

@anthonynoto @Dboybruh @elonmusk @elonmusk if you didn’t know Anthony Noto yet, you’ll soon get to know him anyway. I personally know no other CEO who reminds me of you like he does.

@elonmusk DM me if we can help with anything 😉

@DrToddLee @JAMAInternalMed We have a similar situation in the hospital too! Floor outbreak, everyone gets tamiflu

@JAMAInternalMed Realistically, if you're going to expose tens of thousands of people to a drug which causes vomiting with a number needed to harm of six, the data needs to be stronger than this. The data needs to be randomized.

In US nursing homes, initiating oseltamivir chemoprophylaxis for ≥70% of residents within 2 days of influenza outbreak detection reduced 14-day hospitalization risk without affecting mortality. ja.ma/4118g7T

@Tablesalt13 Shit who would have thought?

🚨NEW Sent to me from Ontario - ITS STARTING Builders are RAISING their prices, because starting tomorrow, the province and the Feds are offering huge tax discounts. Pure scum!!

@mbehr_mcgill Monte Carlo simulations and wild type ECOFF mic are woodo magic to come up with new MIC. Don't believe me, have a look at the rationale for AMG breakpoint discussion....btw none of this matters if fda doesn't agree and labs won't upgrade their devices!

I'm curious how we can generate new NTM names faster than most of us can learn, yet they come with interpretative criteria in the susceptibility results. Do we not need some clinical experience to know what works in patients?

@PensareBBall I had the pleasure of watching Scottie play against OKC in his first year from the court side. The dude has an uncanny ability to scan and read the floor while we had FVV. He always said he felt like he was PG and then we kept giving him different roles!

I've waited for 4 years for Jack Armstrong to say this. I've criticized him for 4 years for NOT saying this. I've hated this media space for 5+ years for pushing this idea that he's a big. Hearing this...okay. respect. Beef squashed.

@BradSpellberg @zacroBID @IdVilchez @JulianVentres @ABsteward @DrToddLee Damn you are so blunt Dr. Spellberg. I keep those thoughts to myself but I agree!

@sarubactam @zacroBID @IdVilchez @JulianVentres @ABsteward @DrToddLee When we eventually win the battle against opinion-based shmidelines, the next major front in the war on nonsense will be CLSI. Breakpoints are made up.

Curious on others practices for oral therapy in gram-negative bacteremia from urinary source. Are you using keflex, amox/clav, plain amoxicillin? Other oral b-lactams? MIC cutoffs? Dosing? @BradSpellberg @ABsteward @DrToddLee @IdVilchez

@NotA_Bull It's a ponzi stock! Forget the valuation. Core business struggling yet keep selling grand visions of robotaxis and humanoids.

Sold my $TSLA for a profit … I get the hype, but a 360 P/E goes against everything I’ve learned about investing. Are you still holding $TSLA at these levels, or is the math not mathing? lol

@JeffreyLuscombe Most ppl have no clue how the MAID process works to begin with! There are multiple evaluations done to make sure it is the right choice for the patient!

I had a loved one in my family choose MAiD when he was in the last months of painful bladder cancer. I see a lot of people on this platform calling it immoral. The only immoral thing I see is making people suffer when they choose to die on their own terms with dignity.

@FoodProfessor Sure, but they do employ CDn workers and carry CDN products! You are allowed to choose what to cut and what not to cut. For example, I stopped buying American lettuce because the Canadian lettuce is much more tasty and pesticide free! I will pay extra to support CDN products

"It’s been interesting to watch Canadians boycott American products, yet never hesitate to shop at U.S.-owned Costco and Walmart for deals. The boycott has been incredibly selective."

@zacroBID @IdVilchez @BradSpellberg @JulianVentres @ABsteward @DrToddLee There was an opinion aper where a bunch of IDs said use non-B-lactam antibiotics and use at high does. Most authors are GN IDSA guidance doc: pmc.ncbi.nlm.nih.gov/articles/PMC85… These recommendations don't make sense and we have had no issues with normal doses of amoxicillin/cephalosporins!

@zacroBID @IdVilchez @BradSpellberg @JulianVentres @ABsteward @DrToddLee This right here is what people miss! The antibiotics concentrations far exceed MIC. That is why we don't see any issues even in bacteremia with GU source work 1st Gen ceph. Most pts have lead in IV. Oral just mopping up whatever little 🦠 left @BradSpellberg