Michael Riffle

@ReedTimmerUSA @localmanweather Security through obscurity.

WHOAH! Someone tried to break into the Dominator 3 last night in downtown Minneapolis! Thankfully they didn’t know how to open the door but they broke off the door latch of @localmanweather side

@ucdmrt They'll ask for 10% next.

After being asked to try 5% FDR to identify a protein. #proteomics and #teammassspec things

Some words of wisdom from this year's chemistry laureate David Baker, whose work has made it possible to design new proteins from scratch. Read more and join us on tomorrow 8 December to hear his Nobel Prize lecture: nobelprize.org/prizes/chemist…

@chrashwood Hmm, I'd probably have it draw each shape as separate requests

New life hack unlocked: use ChatGPT to create SVG containing what I want in figures.

Watch the full event: youtube.com/live/BuJGTn7Oh…

The only acceptable use of UMAP.

@dschweppe1 That's 4.2e11 in ions per minute. Problem solved!

Addressing reviewer concerns today as a means to stay calm in the face of world events may not have been the best idea… Got dinged by R2 as our basepeak intensity was “only” 7e9. So that I can educate myself, what average basepeak intensity means “high quality” data to you?

Come join the OSU proteomics community! We're hiring a senior staff scientist at @OhioStatePIIO run by @Zihai to direct a mass spec proteomics facility to monitor immune proteins in cancer. A great opportunity for independent MS researchers! DM for details osu.wd1.myworkdayjobs.com/OSUCareers/job…

@J_my_sci But doesn't that mean that subsequent analysis has no value?

Needs to add a points and possibly a combo counter.

Metaproteomics conference in Norway in January sounds fun!

Great lineup!

Come listen to my boss yap.

Jayden Daniels Hail Mary but with Celine Dion singing

@wfondrie Ooh, I didn't know about this one. Nice.

5. timsrust - open-source access to data files from the Bruker timsTOF instruments. github.com/MannLabs/timsr…

Seems like a good time for a list some of my favorite truly #OpenSource #proteomics tools. In no particular order: 1. Comet - The Sequest algorithm for everyone. github.com/uwpr/comet

This is a very interesting exchange. It kind of blows my mind that @NIH -funded software isn't required to be open source.

@DemichevLab Mostly it's just that "the cloud" can mean so many different things to different people... Twitter doesn't allow enough room for me to really clarify, so I'll send a GitHub issue. Thanks for the reply

@sciencehacker Hi Michael, is it run on local infrastructure? I've been asked not to amend the clauses in the license though. It will however become more clear in the next couple of months what we want to do about cloud use in academia.

DIA-NN 1.9.2 is out! There are some major improvements, please check the release notes github.com/vdemichev/DiaN…

@byu_sam If it opens the doors more for non native English speakers, I think that'd be great for science.

What effect will chatGPT have on the quality and clarity of scientific publications?