Fully Integrated and Maximally Entangled

most ppl accept stress can cause high blood pressure/heart disease and that those are nevertheless very real and serious conditions. but if you say stress can cause long covid, me/cfs, fibromyalgia etc, one side denies it and the other thinks it means those conditions aren’t real

@SteveJonesmt your position frees either spouse from any obligation to participate in sex at all AND legitimizes making out wantonly without any intention of participating in sex

@SteveJonesmt most people who have sex within a romantic partnership want their partner to take and active interest in and participate in their orgasms. you and your spouse are of course free to make any other arrangement that works for the two of you. but…

if every time a woman made out with her husband before bed she got to have a mind blowing orgasm i bet we wouldn’t have to have this cursed discourse

Housing shortages discourage younger families from moving in and older residents from downsizing; school enrolments fall and communities age even faster than they otherwise would economist.com/interactive/un…

@RagingZionist23 every relationship is different but i stand by what i said, purely as an issue of statistical probabilities

@seran72 Do you know anything about the fucking topic? Having an orgasm isn't what makes a woman want or not want sex in dead bedrooms. You don't even understand the topic but have a lot of thoughts on it.

@JPaulNorton doesn’t sound like “marriage” to me but you do you

@seran72 I bet if we all accepted the fact that women are far less responsible for their husband’s orgasms and far more responsible for their own, they wouldn’t have this issue at all.

@enigmartyr you’re projecting your own issues onto what i said

@seran72 Why is the utmost extreme of human pleasure the mortal flesh can muster the bare minimum price necessary to get a woman to do anything that isn't perfectly self-serving?

@__TheBaron__ and there are men who intensely dislike their wives or don’t find them hot enough or whatever. neither one changes what i said

@seran72 Unlikely, there are a number of people here who REALLY despise their husbands. Perimenopause has some serious intense effects on some people.

@SonsofLiberty72 you’re making a lot of assumptions about how other people’s relationships work

To be quite honest if she’s married and hasn’t taken the time to explain what gets her off to her husband and practice it to the point that he knows what to do without being told…that’s on her. Sure for a bit it would feel like work. But eventually it would happen without question and on a regular basis and it wouldn’t even be a second though. Communication.

@seran72 EXACTLY. Speak on it, sister! 🎙️

Nobody says insulin is overused because diabetes is common. Nobody says inhalers are overused because asthma is common. But when depression is treated, suddenly people call it "overprescribing." Mental illness is still judged differently from physical illness. p.dw.com/p/5ECyE?at_med…

this is a pro moss account

In my model, continual mast cell activation acts on the GR to continue the "cortisol blind" leading to hypervigilence and sustained inflammation. It continues the norepinephrine cascade until exhaustion sets in. At some point the systems can no longer sustain the energy production needed for hyperimmune responses.

A hidden viral protein may be one of the key drivers of severe COVID-19 lung damage. ➡️ Researchers found that #ORF8, an accessory protein secreted by SARS-CoV-2, can “reprogram” lung macrophages, making them more susceptible to infection and triggering pyroptosis—a highly inflammatory form of cell death. 1/

Another study shows cerebral hypometabolism in #LongCovid patients with PEM. Cerebral hypometabolism is a decrease in the brain's ability to turn glucose into energy, leading to a severe cellular energy deficit. journals.sagepub.com/doi/full/10.11…

Long Covid threatens too many systems at once: labor policy, disability systems, infection-control(/narratives), health-care capacity, psychiatric and functional medicine turf, public-health credibility, and economic normalization. When a disease is expensive to acknowledge, institutions($$$$) tend to invest in disease explanations that offload liability: Stress. Beliefs. Deconditioning. Anxiety. Maladaptive nervous system patterns. These explanations may describe one layer of illness, but they also conveniently relocate responsibility back into the patient. This also happened with ME/CFS and HIV/AIDS.

C'mon @WIRED, you have a chance to do better. Instead of amplifying pseudoscience, why not talk to the patients living with #LongCovid and the researchers studying its biology? Levinovitz is not a physician, neuroscientist, or virologist. His expertise is in religion. Try again!

@bdquinn The irony is that Trump is the most socialist president since Nixon

A few things come to mind. One of the most important lessons from modern medicine is that progress follows biology. Patients with diabetes aren't asked to prove their illness through symptom questionnaires alone. We measure glucose metabolism. No one diagnoses a heart attack based solely on fatigue and chest discomfort. We measure biomarkers, blood flow, and tissue injury. We don't debate whether skin cancer exists because a patient reports a suspicious mole. We examine the tissue, study the biology, and make a diagnosis. The path to treatment has always been the same: understand the biology. That is why I find the comparison in this paper between complex disorders and multiple sclerosis compelling. The transformation of multiple sclerosis did not occur because people became more sympathetic to patients. It happened because researchers developed tools that allowed them to see the disease. MRI revealed lesions. Immune profiling uncovered underlying mechanisms. Biomarkers provided objective measures of disease activity. Biology changed everything. Complex disorders are in the midst of the same scientific ambition. The future is not asking physicians, researchers, policymakers, or society to simply believe patients more. The future is generating a level of biological understanding that makes these diseases impossible to ignore. In this paper there are excellent highlights for deeper testing and I agree, we should be investing aggressively in: • 7T MRI to visualize the brainstem and autonomic control networks• • PET imaging to understand neuroimmune activity and neuroinflammation • Advanced immune profiling to characterize the cellular and molecular drivers of disease • Cerebral blood flow measurements to quantify physiologic dysfunction • Longitudinal studies that connect biological changes to patient outcomes (oh how we need these). • I'd also add AI-driven research to add speed and depth These technologies and approaches give us the opportunity to move beyond broad symptom categories and begin identifying the biological pathways that drive illness. Medicine advances because better biology leads to better diagnostics. Better diagnostics lead to better clinical trials. Better clinical trials lead to better treatments. Better treatments lead to health. That is how we transformed diseases like multiple sclerosis. That is how we transformed cancer. That is how we transformed cardiovascular disease. And that is how we will transform and treat complex neuroimmune disorders. When patients ask me why research matters, when all they need is better care: This is why. Better science drives better care. And the exciting part is that we can do this now. We have technologies that previous generations of researchers could only dream of. We have advanced imaging. We have immune profiling. We have AI. We have wearable devices. We have large clinical datasets. We have unprecedented computing power. The challenge is bringing the data, technologies, researchers, clinicians, and patients together in ways that allow us to see the biology more clearly. That is why expert collaboration matters. No single lab, institution, specialty, or dataset will solve these conditions alone. Progress will come from connecting expertise across neuroscience, immunology, autonomics, imaging, computational biology, and clinical medicine. The opportunity is here. @CODA_research is following a specific path: finding answers for patients. CODA CCD unites 8 experts in the field and then will go out to 50 more experts on the best ways to evaluate and treat craniocervical dysfunction. Immune studies (Anktiva and Inspiritol) are based on specific exploration of biomarkers, subgroups. Vagus nerve modulation shows huge promise for RA - how do we bring it to our diseases. AI data specialists - both internal and our partners - are using multiomics and clinical data to subtype and get a clearer picture of underlying biology. This is just a small amount of where we're going with our partners. And we partner with as many leading scientists and other foundations - we believe we are stronger together. One of the greatest moments we had this year, was coming together with @actionforme Schmidt Initiative for Long COVID, @PlzSolveCFS @weandmecfs to get a massive @DecodeMEstudy long-read genomics study launched - with an amazing ￡4.5 invested by th UK govt because of this partnership. That wasn't my idea - it was @SonyaChowdhury and team's brilliant idea and we were glad to be a part of it. I have a child in this space and I talk to patients every single day who are suffering beyond measure. I know patients can't wait for better care. The more we work together, the more experts engage, the better we can use science to accelerate real progress and the more people we can help. Quickly. Thank you @dysclinic et. al. for the paper. And @BrainInflCollab for calling it out for me this morning. buff.ly/HqR7NKH

“The scheme worked because of the system, not in spite of it. The secrecy walls built to hide operations from China and Russia hid the fraud from the CIA itself.” if proven, this would constitute a deep state