Basem Al-Shayeb, Ph.D. 🧬 (@themicrobeguy) - Twitter Profili

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Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy·19 Ağu

🚨 Today, we’re thrilled to share our study expanding the gene editing toolbox to enable virtually any kind of edit in gene transcripts at the order of thousands of bases. A thread 🧵👇(1/n) biorxiv.org/content/10.110…

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Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy·2 Eki

A great day for RNA, and for groundbreaking science performed at biotech companies! #NobelPrize

The Nobel Prize@NobelPrize

“Ten years ago I was kicked out and forced to retire.” Our new medicine laureate Katalin Karikó (@kkariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges. Ten years ago, Karikó was still doing all her experiments by hand but today she has been awarded the medicine prize for her research on mRNA, which led to the development of COVID-19 vaccines. Listen now:

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Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy·28 Eyl

Thanks @Smanski_Lab for the invite! It was wonderful to share some of our work and hear from faculty and students. Till next time!

Building Better Bugs@Smanski_Lab

Thanks @themicrobeguy for a great seminar on engineered trans-splicing. Great our alumni crushing it @umncbs

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Building Better Bugs@Smanski_Lab·28 Eyl

Thanks @themicrobeguy for a great seminar on engineered trans-splicing. Great our alumni crushing it @umncbs

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Zak Doric, PhD@zakdoric·1 Eyl

Had a blast interviewing @themicrobeguy at our @SkyDeck_Cal x @a16zBioHealth student mixer last night. From spotting a synthetic biology flyer in undergrad to quickly becoming a trailblazing scientist-entrepreneur in that field -- what a remarkable journey it's been 🚀@UCBerkeley

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Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy·31 Ağu

Thanks to @JuliaBauman2 for this neat recap of our recent work! Stay tuned for updates 🙂

Julia Bauman@JuliaBauman2

A potentially high-efficiency alternative to making large genome edits: making large RNA edits via splicing! Very cool proof-of-concept from @jacobborrajo @Kamyab_J @themicrobeguy & @BlaineyLab in @biorxivpreprint

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Basem Al-Shayeb, Ph.D. 🧬 retweetledi

CRISPR Medicine@CrisprMedicine·22 Ağu

@MIT @themicrobeguy @jacobborrajo See also thread explaining Splice Editing by Amber Bio co-founder @themicrobeguy: twitter.com/themicrobeguy/…

Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy

🚨 Today, we’re thrilled to share our study expanding the gene editing toolbox to enable virtually any kind of edit in gene transcripts at the order of thousands of bases. A thread 🧵👇(1/n) biorxiv.org/content/10.110…

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Forbes@Forbes·6 Ağu

By targeting RNA rather than DNA, Amber Bio aims to treat multiple genetic diseases with fewer safety risks. trib.al/HOxDx7z

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BioWorld@BioWorld·7 Ağu

Newco news: With $26M in funding, RNA editing firm Amber Bio targets diverse mutations bioworld.com/articles/69970… #biotech #pharma

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CRISPR Medicine@CrisprMedicine·4 Ağu

Latest CRISPR news -> shorturl.at/fDIS7 🚀Amber Bio launches with an oversubscribed $26M seed financing round, which will be used to develop RNA-editing therapies for previously undruggable diseases. Co-founded by Basem Al-Shayeb, Ph.D. & Jacob Borrajo, & they are #hiring

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Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy·22 Ağu

We're on a mission to develop intrepid new approaches to RNA medicines. Towards commercialization, we’ve announced the launch of Amber Bio this ~AUG~, with funding from visionary teams at @Playground_VC, @a16z, @EliLillyandCo & more. If this work interests you, we're hiring!

Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy

🚨 Today, we’re thrilled to share our study expanding the gene editing toolbox to enable virtually any kind of edit in gene transcripts at the order of thousands of bases. A thread 🧵👇(1/n) biorxiv.org/content/10.110…

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Basem Al-Shayeb, Ph.D. 🧬 retweetledi

Kamyab Javanmardi, Ph.D. ⚛️@Kamyab_J·19 Ağu

Excited to share our recent study describing a new gene editing approach capable of extensive multi-kilobase edits. When DNA is giving you problems look into the RNA. Much more to come, so stay tuned. biorxiv.org/content/10.110…

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Arturo LoAIza-Bonilla, MD MSEd@DrArturoAI·19 Ağu

CRISPR-Cas and Splicing at kilo base level 🤩🤯👨🏻‍🔬👩‍🔬🧬

Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy

🚨 Today, we’re thrilled to share our study expanding the gene editing toolbox to enable virtually any kind of edit in gene transcripts at the order of thousands of bases. A thread 🧵👇(1/n) biorxiv.org/content/10.110…

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Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy·19 Ağu

@Dylan_Smock 🙏🙏

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Dylan Smock@Dylan_Smock·19 Ağu

@themicrobeguy Congrats Basem!! Awesome work 🎊🎉🥳

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Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy·19 Ağu

🚨 Today, we’re thrilled to share our study expanding the gene editing toolbox to enable virtually any kind of edit in gene transcripts at the order of thousands of bases. A thread 🧵👇(1/n) biorxiv.org/content/10.110…

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Basem Al-Shayeb, Ph.D. 🧬@themicrobeguy·19 Ağu

@l_loeff Thank you, Luuk!

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