Tim

@hubermanlab What are your thoughts on magnesium taurate? It seems more calming than any other magnesium. Curious if you’ve tried this variant @hubermanlab

If your dreams are too vivid, drop the theanine. And yes Mag Bisglycinate and Threonate are interchangeable for sleep but Threonate has some additional benefits. Find a brand with 3rd party testing. Oh and apigenin alone does the job for some people. Sweet dreams.

After being inactive for the last two months (1 month ago I had acl surgery), my vo2 max hasn’t plummeted as much as I would have thought. It could be that Apple Watches only let u decrease by a maximum of 1 point per measured event. However, if I truly only lost 5 points of vo2 max after tearing and reconstructing the acl, along with breaking a bone, I’ll be overjoyed. At the time of the acl injury, I was around a 3:50 marathon runner. Today I was a 19 minute half mile walker! One thing I love about cardio is watching numbers get better. Well, it’s only up from here! Hopefully I’ll be able to tolerate these walks. This was my first walk without a brace.

@davidfowl @aspiredotdev We are even more vendor locked on aws lol. But yeah I completely agree.

@timdoke @aspiredotdev Being vendor locked isn't the end of the world, until it is.

This was a pretty incredible journey. I rememeber when .NET had its own version of distributed tracing (didn't everyone before otel??). Now it's a no brainer, if you aren't using otel for tracing you should be. aspire.dev/dashboard/stan… #otel #aspiredev @aspiredotdev

Yeah we’re in a tricky situation now where if i were to add otel, it would just duplicate everything from dd. So thats a no-go. Especially when we’re talking about the scale my job has. Even if i were to start over (no devops setting up apm for example) I doubt i could get us to switch.

@timdoke @aspiredotdev Yea that’s the point of the standard 😬. You can always be vendor locked

@baldguy_58 @hubermanlab Yep. I completely get it. But there are doctors who prescribe this stuff. Doubt they are surgeons though.

@timdoke @hubermanlab She's supposed to say no. She's covering her own ass. Surely you understand that?

If BPC-157 is banned by USADA does that mean that it works?

@WilliamPenn88 @hubermanlab Wish my dr did that

@timdoke @hubermanlab My doc ordered it for me

@DrJesseMorse Do u get this stuff from an online shop, or from a compounding pharmacy?

I practice what I preach. Here is the current peptide stack I’m currently on for health optimization, cutting, energy optimization and healing: Monday Reta - 1 mg AM NAD+ - 25 mg AM CJC/Ipa (no DAC) - 250 mcg QPM GHK-Cu / BPC-157 / TB-500 - 1.5 mg / 500 mcg / 500 mcg AM Tuesday Thymosin Alpha 1 - 1.5 mg AM CJC/Ipa (no DAC) - 250 mcg QPM Wednesday NAD+ - 25 mg AM CJC/Ipa (no DAC) - 250 mcg QPM GHK-Cu / BPC-157 / TB-500 - 1.5 mg / 500 mcg / 500 mcg AM Thursday Reta - 1 mg AM CJC/Ipa (no DAC) - 250 mcg QPM Friday NAD+ - 25 mg AM CJC/Ipa (no DAC) - 250 mcg QPM GHK-Cu / BPC-157 / TB-500 - 1.5 mg / 500 mcg / 500 mcg AM I recently completed my annual cycles of Epithalon (sleep), and mitochondrial rejuvenation (MOTS-c, SS-31). Up next anti-aging: FOXO4-DRI Mind you this is only the injectables, I have about 30-40 oral supplements that I take daily to complement the injectables. THIS IS NOT MEDICAL ADVICE. THIS IS ME BEING TRANSPARENT.

@Halmsy @hubermanlab Injectable or pill? Also, what kind of graft are u getting? I got a quad graft and while it may me better long term, the swelling u get is crazy. I had tried the pill before a long time ago. It gave me all kinds of stomach issues.

@timdoke @hubermanlab I'm getting ACL surgery. Intend to use it

@Kmart3501 @hubermanlab That sounds insane. At least if it’s a pharmacy, you should be confident in getting a good source, even if it’s Chinese. With online sales, they can just put a research label on it and be free from consequences.

@timdoke @hubermanlab No American pharmacy compounds BPC-157. They buy Chinese peptides and mix them up for you.

I suspect it’s a bit different when u are absolutely going to get surgery. If, for example, I got some kind of cancer in 2 years around my knee because peptides caused unconstrained growth, the surgeon doesn’t want any culpability. I personally don’t trust these online sources. I took oral bpc157 a few years ago and wound up getting extreme stomach aches.

@timdoke @hubermanlab I have a torn meniscus (no surgery yet 🤞) and grade 2 MCL sprain. My doc said “you can try, I don’t think it’ll make it worse” lol

Yeah they never bothered to tell me that once u get a fusion, u get stuck in a cycle of needing more. I was extremely angry when I found that out. So far at least, ive been able to avoid further surgery on my neck. May not be possible for my whole life, but i can hope. Your situation is much better.

@timdoke Yeah, that's why I'm really happy I'm able to do the replacement, especially since I have a bulge at C5-6. If I did a fusion at 6-7, I would almost be guaranteed to have to do another fusion at 5-6 in a few years.

Well, won’t be setting any PRs this summer. Neck surgery in 2 weeks to fix a disc extrusion that hasn’t responded at all to conservative treatment. Weakness has continued to worsen after PT, prednisone, and two cervical epidurals. Currently, I can do 22 reps of a 30 lb dumbbell skull crusher with my right arm and (barely) 2 with my left. At this point, the longer I wait to have surgery, the less chance there is that the nerve makes a full, or close to full, recovery. Likely won’t be able to do anything other than walking for ~2 weeks, no running for 4+ weeks, and no heavy lifting for ~12 weeks. Honestly, the hardest part will be not being able to pick up/throw/play with my kids for a few weeks after surgery. 2 main goals after surgery: 1. Don’t do anything dumb that extends recovery. 2. Don’t get too fat. 😂

@Brady_H Ok. Talking u out if it. This may just be me spouting nonsense. But, have u tried ice baths after running? Those are amazing for recovery/soreness etc.

I’m *this* close to purchasing compression recovery boots. Talk me out of it (or into it).

@Polymarket Now we need ebola to mix with hantavirus so all the science nerds can get a hardon.

JUST IN: Congo confirms major Ebola outbreak, with 246 suspected cases.

I just had acl surgery. While the surgeon was “under the hood” she checked out the full status of my knee. She said my knee was pristine, with zero wear and tear damage. This is despite running for the last 2.5 years. So I definitely agree with you! Hopefully after recovery, my knee will still be pristine.

Running and Knee Osteoarthritis... I treat a lot of runners... one of the most common questions I get is whether running is bad for your knees. Their friends tell them to stop running... online influencers occasionally scream it into the ether. Your friends are not right. After 30 years in practice and a continuous, and pretty thorough look at the research, I can tell you that the evidence consistently points in the opposite direction. Running, at recreational levels, appears to be protective against knee osteoarthritis, not harmful. Let's get into this...

@JoeMama420lmao2 @elonmusk I’m a fan of the Oakenfold version as well. I think it got dmca’ed tho cuz i can’t find it on most streaming platforms.

@elonmusk There’s a Paul Oakenfold CD where he mixes this into the beginning of a song. It’s brilliant.

Name a video game that you've easily put 1,000 hours into Gifs only

@tiga_style How the heck do u avoid serious injury running like this? I tore my acl and had it surgically repaired 2 weeks ago from a hyperextension during marathon training. It wasn’t even close to this fast. That speed would make me incredibly nervous now, even if I could do it.

POV: you refuse to get dropped on the long run. The pros and cons of running with people faster than you: Pro: they make you better. Con: they make you question every life decision that led you to that moment. I can’t let them keep getting away with this…