Cisy

Excited to see our work with @enigmabrains CHR-P WG come out today in Molecular Psychiatry! CHR-P showed global #topology differences in #brain structural covariance network compared to controls, while future transition linked to frontotemporal networks nature.com/articles/s4138…

🎉Our paper is published on Alzheimer's Research & Therapy! We show that MBI-related functional network disruption is linked to worse function and faster amyloid-dependent cognitive decline. 🔗Check the paper now: doi.org/10.1186/s13195… @HelenJuanZhou

Do developmental variations in functional connectivity really mean what we think? Byeon, @TingsterX, et al. suggest they may actually reflect shifts in how brain activity spreads. Intriguing implications for measuring and understanding brain development! biorxiv.org/content/10.110…

Our latest work is online today @ScienceAdvances ➡️Brain connectivity in carriers of high risk mutations for #autism and #schizophrenia U-turns across adolescence (hyper -> hypo) ➡️This switch is driven by synaptic remodeling science.org/doi/10.1126/sc… Full explainer below 👇

Using the connections of commissural neurons as an example, Lent et al. propose that expanded brain circuits may constitute a “connectomic reserve” that enables neuroplasticity to occur throughout life, and that may be a proxy for cognitive reserve. shorturl.at/5HNlS

Brain structural networks underlying language | Physiological Reviews | American Physiological Society journals.physiology.org/doi/full/10.11…

You don’t need a brain to benefit from a good night of sleep. Despite lacking a central nervous system, jellyfish and sea anemones have sleep patterns remarkably similar to those of humans, researchers report. Learn more: scim.ag/49qn4k2

Today in @NatureMedicine we report that AI can predict 130 diseases from 1 night of sleep🛌 We trained a foundation model (#SleepFM) on 585K hours of sleep recordings from 65K people—brain, heart, muscle & breathing signals combined. AI learns the language of sleep🧵

Long-range axon branching: contributions to brain network plasticity and repair — a Review by Linda J. Richards, Cheng Huang, Adam Q. Bauer & Jin-Moo Lee nature.com/articles/s4158…

Bottom line: We may have been measuring the wrong things about sleep. Total hours, REM percentage, deep sleep duration - none predicted brain cleaning as well as norepinephrine pulse frequency did. cell.com/cell/fulltext/…

🧠Researchers from NUS Medicine and the Institute of Mental Health #IMH have uncovered how brain networks are organised differently in young individuals at Clinical High Risk for psychosis, offering fresh insights into how the condition may develop. medicine.nus.edu.sg/news/researche…

Tsang et al. reviewed 13 studies combining TMS with intracranial EEG in humans and non-human primates. They found that stimulation can rapidly alter neuronal activity and connectivity, with some effects persisting for extended periods. tinyurl.com/yver3s93

Sleep deprivation causes intrusive memories via the disruption of neural circuits.

p-tau217, the breakthrough blood test, prediction of amyloid-β burden and Alzheimer's disease in people with no symptoms, no cognitive impairment jamanetwork.com/journals/jaman…

Very insightful and inspiring talks and fruitful discussion in the morning. A great line-up in the symposium of TMR. Come join us if you’re nearby

Can't say thanks enough to @HelenJuanZhou, @Jimmy_Lee_CK, Maria Jalbrzikowski, @hernaus_tweets, @MNNDL_Lab and @enigmabrains Clinical High Risk for Psychosis Working Group giving really valuable feedback and support along the way.

Excited to see our work with @enigmabrains CHR-P WG come out today in Molecular Psychiatry! CHR-P showed global #topology differences in #brain structural covariance network compared to controls, while future transition linked to frontotemporal networks nature.com/articles/s4138…

Epic work led by @ganjgahi is out in Nature Medicine... data-driven clustering of MS finds 3 distinct states, early/mild, active, advanced, w/ transition to the advanced state only occuring through the active state... replicated twice! doi.org/10.1038/s41591…

Depression often co-occurs with chronic illness, e.g. heart disease, diabetes and obesity, which may be explained by chronic inflammation & metabolic dysfunction. But, what is the course of immunometabolic dysfunction in depression and how that may relate to brain changes?🧵1/6

Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan | doi.org/10.1371/journa… How does blood perfusion map onto canonical features of brain structure and function? @AsaFarahani investigates @PLOSBiology ⤵️

NetBat - a new method for harmonizing structural connectomes based on stochastic block models Seems to perform better than Com- and Cov-Bat when applied to connectivity matrices sciencedirect.com/science/articl…