Travis Lines

Urinary nitrite testing introduces diagnostic confusion without adding value with regard to the decision to treat False +ve: asymptomatic bacteriuria, contamination False -ve: UTI due to non nitrate–reducing bacteria (e.g. Enterococcus, Acinetobacter species) H/t @ABsteward

What is the role and the sensitivity and specificity of a urinalysis for the diagnosis of urinary tract infections? 🧪🧫🔬

Great recap, @PaulSaxMD. Just sharing a few other #ESCMIDGlobal2025 pearls from the slides that caught my eye: - Mortality was ~3x higher when source control lagged - antibiotic choice only goes so far. - Flu(clox)acillin nephrotoxicity is real, not just an AKI epiphenomenon. - PCN G may be better than ASPs for PSSA (posterior Pr superiority 0.89 for mortality, 0.98 for nephrotoxicity). - Cefazolin non‑inferior to fluclox with lower early mortality and less nephrotoxicity; HR 0.87 (95 % CI 0.67–1.15). And < 1 % of > 6,200 patients in high‑quality SAB RCTs (SNAP + BALANCE) were enrolled in the U.S. 😬 #SNAPtrial #StaphBacteremia @syctong @Josh_S_Davis

SNAP/COLCEBA trial session starting now @syctong @Josh_S_Davis @ABsteward Staph aureus causes 1 million deaths per year worldwide. Less than 4.5k randomized in staph aureus bacteremia. Randomized care is better than random care. SNAP platform started on a napkin. #ESCMIDGlobal

You could be forgiven for taking from this graph that Twitter users in the UK have well more than halved, where the decline is a more modest 30%.

@LiangRhea That line genuinely helps. For all intents and purposes I dressed as I would have done on a normal clinical day, just picked my nice outfit.

@travislines I'm intrigued that it specifically says NO suits, ties or jackets 🤯

A possibly radical thought, but founded on good #MedEd and #equity grounds- surely the time is ripe for a progressive College (any College!) to say y'know what? You're right. Please present for examinations in any dress that is tidy and appropriate. 1/2

Huge loss for nurses.

This is a brilliant way to display seats and I'm shocked it's never been done before. economist.com/interactive/uk…

The national service nonsense does give me the opportunity to tweet one of my favourite recent bits of polling when Ipsos actually ran the famous "Yes Minister" questions as a randomised experiment, and showed that it worked.

🧵 1/ What’s at stake with race-based equations for lung function? Clinical, occupational, and financial reclassifications for millions of patients. I’m delighted to share this labor of love, published today in @NEJM and unveiled at #ATS2024. nejm.org/doi/full/10.10…

Matt Guelfi kept his promise 🥰 The Bombers favourite had a beautiful reason for his painted nails in Saturday's win.

Very pleased to see a positive step here; however, boggles that other disciplines such as physios and med students have not been included. Our students show up, work, and are excellent members of the team. They should not be made to do it for free. abc.net.au/news/2024-05-0…

Nothing portends the collapse of society quite as much as the way people stand right next to the baggage carousel at airports when their bags are nowhere in sight.

@MayoClinicINFD Strep bovis/gallolyticus

Weekend Digest Name the Pathogen Five Clues 1. Gram-positive coccus 2. Bacteremia 3. Endocarditis with large vegetations 4. Colonic neoplasia 5. Penicillin / ceftriaxone treatment

@PeterDTAdams @realCarrickRyan It’s also worth noting that this is much less than the 170K that Google gives. (And also worth thanking you for highlighting that students are not paid on placement but ought to be!).

@PeterDTAdams @realCarrickRyan May assist with this discussion to know that junior doctors’ wages in each state are set by an enterprise bargaining agreement, not the award (which you’ve referenced here). Interns make about double what’s in the award + overtime. Most make about 100K #page22" target="_blank" rel="nofollow noopener">qirc.qld.gov.au/sites/default/…

Policing is probably the only industry where collective punishment against them is cheered on. There are 60,000 Cops in Australia. Nearly all have chosen a poorly paid career because they genuinely want to help their community. Yet are despised due to the actions of a few.

@laocarinadetapi @DrNeilStone Yep!

@DrNeilStone So... How do you say encephalitis? "Enkephalitis"? With a hard "k"?

For the cephalosporin antibiotics in the UK we say kefazolin, keftazidime,keftriaxone rather than Sefazolin, seftazidime, seftriaxone as in the US. I think the hard "k" is correct as the "ceph" is from the Greek word"kefali" - meaning "head"

26/26 Small things like these by Claire Keegan. Rounding out the Keegans, and rounding out the reading challenge, this short story sees a fundamentally ordinary man grapple with the horror of Magdalen laundries. It’s quietly excellent

25/26 So late in the day by Claire Keegan. A novella set in County Wicklow that tracks the breakdown of a relationship and subtle misogyny. Very good.

Another year another reading list. This year will be a busier one at and outside of work, but I’m determined to keep to a goal of 26 books read. Keep me honest below!