Val Pye

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Val Pye

Val Pye

@val_pye

Katılım Temmuz 2019
942 Takip Edilen315 Takipçiler
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Oliver Acton
Oliver Acton@OliverActon3·
Delighted to share that our manuscript describing the structural dynamics of SAMHD1 catalysis using time-resolved cryoEM and extensive biophysics is now available online. Fantastic collaboration between several labs and STPs @TheCrick nature.com/articles/s4146…
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Jacob Lewis 🧬 📷
Jacob Lewis 🧬 📷@Jacob_Lewis90·
🌟 Big News! 🌟 the Lewis lab is open for business @MolHorizons. A new chapter of discovery and learning awaits. Thrilled to start this journey and tackle some challenging questions!
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Thomas Miller
Thomas Miller@TCR_Miller·
Clocking off work for the year. Thanks to everyone in the group, @ccs_ku_dk and @UCPH_health for making 2023 so enjoyable. Thanks also to @sarahruidiaz for the amazing birthday cake today! Enjoy the holidays. Looking forward to 2024.
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Val Pye retweetledi
Peak Proteins
Peak Proteins@PeakProteins·
'Building' up to the Holiday Season - Day 15. Protein Structure Determination at Peak Proteins (part of Sygnature Discovery). This structure is ATP synthase which catalyses the formation of the energy storage molecule adenosine triphosphate (ATP).
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Peak Proteins@PeakProteins

'Building' up to the Holiday Season - Day 14. NMR at Peak Proteins (part of Sygnature Discovery). We’re very excited to be offering NMR data collection and interpretation for our clients and have a number of projects underway. 🙌🏽🧲

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Peak Proteins
Peak Proteins@PeakProteins·
'Building' up to the Holiday Season - Day 6. Protein Expression and Purification at Peak Proteins (part of @SygnatureDiscov ). At Peak Proteins we can express and purify proteins from E. coli, insect and mammalian cells. lnkd.in/d5Qa27t7
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Peak Proteins@PeakProteins

Day. 5 'Building' up to the Holiday Season - Day 5. Mass Spectrometry at Peak Proteins (part of Sygnature Discovery). In addition to part of our QC, we offer Mass Spectrometry as a standalone service. Find out more lnkd.in/d4GittbV

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Peak Proteins
Peak Proteins@PeakProteins·
'Building' up to the Holiday Season - Day 4. At Peak Proteins we use the Fida 1 platform from @FIDATechnology for a number of our client projects. 📖Read more about how we use Fidabio lnkd.in/eKy28Q_4
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Peak Proteins@PeakProteins

'Building' up to the Holiday Season - Day 3. We have a dedicated team of membrane protein scientists. Along with our colleagues at @SygnatureDiscov we recently published a review in, focused on the key aspects of modern GPCR drug discovery. lnkd.in/dTJWaFrJ

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Peak Proteins
Peak Proteins@PeakProteins·
'Building' up to the Holiday Season - Day 2. Day 2 - Horseshoe Crabs and Endotoxins! At Peak Proteins (part of @SygnatureDiscov), we are experienced in minimising endotoxin levels where required by our clients for assays. Read to learn more ! lnkd.in/et3JTn9T
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Peak Proteins@PeakProteins

'Building' up to the Holiday Season - Day 1. We're counting down to the holidays with a series of models highlighting what we do at Peak Proteins (part of @SygnatureDiscov ). First up is our bioreactor @InforsUK - read more peakproteins.com/labfors5-bench…

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Emma Hesketh
Emma Hesketh@HeskethEmma·
If you are interested in using #CryoEM and #Chemistry to study PROTACs for cancer treatment do a iCASE #PhD with James Hodgkinson, John Schwabe and me @LeicStructBio and @PeakProteins. Click here and scroll to the bottom ⬇️🔬more.bham.ac.uk/mrc-aim/phd-op…
@MRC_AIM_DTP@Impact_Aim_Mrc

🚨We are delighted to announce that recruitment for 2024 studentships is now open! Projects are across the 3 partner institutions @unibirmingham @uniofleicester and @UniofNottingham Application forms and information are available on the AIM website tinyurl.com/3x4zj3zk 🧵

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George Chiduza
George Chiduza@ChiduzaGeorge·
Excited to share another paper from my time @TheCrick! Thanks to everyone involved, @e_almacellas @Stefano_De_Tito @val_pye @Alex_van_Vliet @sharontooze01. Looking forward presenting this work @LivUniISMIB next week. #autophagy #atg9 #atg2 #lipid #scramblase
George Chiduza@ChiduzaGeorge

Autophagy is a conserved degradation pathway in eukaryotes. However mammals have two copies of the lipid scramblase ATG9. We report here a detailed molecular and functional characterization of the more rapidly evolving and understudied paralog, ATG9B. doi.org/10.1080/155486…

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The West Lab
The West Lab@SCWestLab·
Our latest paper uses structural biology, biochemistry & biophysics to reveal the two-step catalytic mechanism of the human nucleotide pool sanitiser DNPH1. This will aid the development of novel inhibitors, which may be of use in breast cancer treatment. nature.com/articles/s4146…
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Keşfet

@TheCrick @thermofisher @Jacob_Lewis90 @MolHorizons @TCR_Miller @ccs_ku_dk @UCPH_health @sarahruidiaz