Tassilo Wachsmann

I am so excited to share our new paper in @Nature: the first programmable, site-specific integration of a large DNA payload into T cells in vivo. A single IV injection results in therapeutic levels of TRAC-targeted CAR T cells in multiple models. #Ack1" target="_blank" rel="nofollow noopener">nature.com/articles/s4158… a 🧵

What if we could engineer T cells in the body, making CAR T vs cancer, autoimmune diseases, and other applications far more practical, much less expensive? A step forward today via genome editing T cells nature.com/articles/d4158… nature.com/articles/s4158…

We are recruiting! If you are passionate about technology development, protein engineering, computational design, directed evolution, chemical biology - please reach out! (The setting is pretty nice too…)

Thrilled to share our new review article from our lab titled 'Rewriting the epigenome: CRISPR tools for biological discovery and therapeutics.' led by @cotero926. Free download for the next 50 days! #epigenetics #crispr #synbio sciencedirect.com/science/articl…

CRISPR tools for T cells: targeting the genome, epigenome, and transcriptome cell.com/trends/cancer/…

Durable epigenetic silencing with a TALE-based editor #NBTNV go.nature.com/4q3YvRE

New Qi Lab Review out on CRISPR Tools for T-Cells led by @waxtla ! @Stanford_ChEMH @bioe_stanford @trendscancer @CellCellPress . Link to DOI in replies.

If you work with T cells, chances are high that you've used CRISPR/Cas9 to knockout genes. But did you know that CRISPR tools can not only engineer the genome, but that you can also directly engineer epigenetic regulation or process RNA, completely without DNA-damage?

When the production editor thinks it's more likely that you used psychedelics rather than a statistical test #publishing #AcademicChatter

@UniFreiburg @LabMinguet @dfg_public @BUnifr @CIBSS_UniFR Congrats Susana, exciting!

Dr. Susana Minguet García/@LabMinguet erhält zum 1.4.2023 eine Heisenberg-Professur der @dfg_public für Synthetische #Immunologie, die an der @BUnifr angesiedelt ist. Außerdem fördert die DFG ihre Forschungen zum Verständnis der Aktivierung von T-Zellen. ufr.link/heisenberg-min…

Great to see our close collaboration with Maastricht UMC+ being published in @AjHematology ! onlinelibrary.wiley.com/doi/10.1002/aj…

New #JITC article: T cell receptor engineering of primary NK cells to therapeutically target tumors and tumor immune evasion bit.ly/3q26Ure

Great science yesterday afternoon full with exciting talks of the ESRs from @enacti2ng! Guys, you rock science! Thanks Marie Curie EU Training Networks #MSCA #ETN! Looking forward to more talks today! Really a pity not to meet in person 🥲

$MRNA

Today we want to share an interview from one of our partners in the consortium: Christoph Trenzinger from STRATEC Cons. Christoph talks about his research and future plans as well as his experience as a PhD student in industry. enacti2ng-itn.cbm.uam.es/index.php?opti…