Sabahat H Zaidi

This will stay. 👇

🟩Heart failure: commonest cause of #pleural #effusion. @JoseMPorcel will discuss this under-represented topic at THE AUSTRALASIAN PLEURAL SEMINARS on Jun 4. Link on 🧵. @tsanz_thoracic @AAB_IP @wabipconnect @PleuralPOCUS @iPulmOG @atscommunity @EuroRespSoc @accpchest @APSRapsr

@anzics What a loss to the intensive care community! RIP

Dear friends and colleagues, It is with overwhelming sadness that we share news of the death of our colleague, mentor and friend, Rinaldo Bellomo. During recent days, both he and his family have received dedicated, expert and compassionate care from some of the finest in our ICU community. We share their pain and sense of loss. Over several decades, Rinaldo has made a profound and enduring impact on ICU practice in Australia, New Zealand and around the world. As a passionate researcher he challenged conventions, championed evidence-based practice in the care of the critically ill and supported countless colleagues in their research careers. As a compassionate mentor, colleague and friend, he touched and enriched numerous lives, and will be greatly missed. His loss will affect our whole community and in due course there will be opportunities to come together to celebrate his life. This will be a difficult time for many, but we know that our memories of Rinaldo’s relentless enthusiasm, warmth, optimism and boundless energy will help us all through the weeks ahead. In lieu of flowers, Rinaldo's family would welcome donations to support his research legacy at …lth-community-fundraising.raisely.com/inmem-rinaldo-… Our sincere condolences and best wishes go out to his family, friends and colleagues. Craig Carr, on behalf of the ANZICS community

People who make $1,000,000 an hour have convinced people making $25 an hour that all of their problems come from people making $7.25 an hour. #LongLiveAmerica #TariffWar

@AnitaHannig "Medical professionals have an integral role in shaping societal attitudes to dying." 👍 Working in four healthcare systems (India, KSA, UK, Aus), I've seen that society's acceptance of death is shaped by religious, cultural, philosophical, and behavioural insights.

@MitoPsychoBio @lsi1123 Hey @MitoPsychoBio, great post and insightful comments. #GDF15 is the molecule that holds so much information both in the homeostatic & non-homeostatic states. Just one point: people who exercise more have HIGHER circulating levels of #GDF15. Ref : pubmed.ncbi.nlm.nih.gov/33589633/

@lsi1123 Increasing energy flow in mitochondria would probably lower GDF15 indeed People who exercise more have lower circulating levels of GDF15

If we look at thousands of proteins (i.e., signals) in the human blood, the protein most associated with chronic physical and mental illnesses is the **same protein** as the top marker for mitochondrial diseases: GDF15 When mitochondria cannot flux energy properly, the cell makes and secretes GDF15 in the blood to alert other cells Some highlight by Cynthia Liu in our group: - GDF15 is the top predictor for most diseases - GDF15 associated with diabetes is among the most significant protein-prevalent disease associations Based on p-value, GDF15 was most significantly associated with disease. - “GDF15 was associated with the most diseases, containing 205 prevalent and 397 incident diseases, generally acting as a risk factor except for three incident diseases (respiratory diseases affecting the interstitium, disorders of magnesium metabolism, and peripheral artery disease).” - “GDF15, similar to its high ranking with protein-disease pleiotropy, ranked second for protein-trait associations, boasting a substantial 428 associations.”Significant associations with many lipid metabolite markers. - Mental disorders like anxiety disorders, depression, and mood disorders, along with mental health-related traits, also exhibited substantial proteomic signatures including elevated GDF15 - “The fluid intelligence score and various types of dementia shared significant proteins such as NEFL and GDF15 (Figure 2G)” - “GDF15, the protein with pleiotropic effects, was causally associated with several autoimmune diseases, including ulcerative colitis and rheumatoid arthritis (Figure 6B).” Data from >53,000 people in the UK Biobank Full paper here: cell.com/cell/fulltext/… Resource to explore your favorite protein or disease/trait of interest: proteome-phenome-atlas.com

Less than 3 hours to #CCRdownunder in Melbourne ➡️ 8 major trial results over 2 days ➡️ In depth discussions ➡️ Full, free livestream criticalcarereviews.com

The best critical care trials in the world. #CCRdownunder

@Diana_A_Sousa @TheLancet @OPTIMAS_UCL @ECSandset Hi, could I please obtain a copy of this editorial/paper? It is currently behind a paywall. The article will not be used for any commercial purposes and will solely serve for academic knowledge. Thank you very much. Sabahat (ICM/ED doctor) Email: sabahat.husain@gmail.com

Happy to share our editorial in @TheLancet on the @OPTIMAS_UCL trial, exploring early anticoagulation in ischemic #Stroke patients with #AtrialFibrillation. Important findings for improving secondary stroke prevention and patient outcomes @ECSandset 👉thelancet.com/journals/lance…

This is gold! Thanks @cliffreid

🧵 Managing Challenging Behaviours in Resuscitation Teams: A Thread for Team Leaders (1/13) Every resuscitation team leader can face difficult team dynamics Here are 6 key challenging behaviours you'll encounter and how to manage them effectively in real-time 🚨

@IM_Crit_ @rbarbosa91 @DYannopoulos He has, hasn't he? I am sure we can fix most medical problems if we can afford the cost of taking one of the most expensive modalities of healthcare to the patient! Expensive toys vs good standard of care. 🤷

@rbarbosa91 I agree, it's magnificent when you read about it and see the videos but the logistics are insurmountable for most places. However, many kudos to @DYannopoulos for moving the needle forward in the field. Huge fan of what they have accomplished!

This is an excellent read about the PA debacle that the NHS has created. People "...capable and motivated to provide care to patients in the NHS... " are sold a dangerous shortcut, which is harmful for the patients and themselves. #physicianassociates shorturl.at/nJ2LF

🧵regarding the useful technique of 'straightening the wire' during central line placement when the plastic guide is no longer within reach. If you do a lot of central lines (or a lot of percutaneous procedures), this technique will come in handy over and over again. (1/ )

Hey EM folks! I have an upcoming presentation to discuss the top emergency medicine papers published this year. Any recommendations? #EmergencyMedicine #topresearch #researchpaper

@clifford0584 Order of priority. 1. PR sponsorship 2. ACEM fellowship Easy peasy. 👍🏼

Job offers decisions, decisions!!!

@ShariqShamimMD @BrooksWalsh ☝🏼I like this guy already.

@BrooksWalsh Name and shame the program. If this doesn’t go to cath with angina, these guys need to stop training fellows.

The ECG that radicalized me. I was a PGY-3. Middle-aged guy with typical chest pain, early AM. Both ED attending and cards fellow say this isn't an indication for the cath lab. Still salty about my attending.

"...seizure prophylaxis was associated with a small, albeit significant, reduced risk for early posttraumatic seizures for mild to moderate TBI; the small absolute risk reduction should be weighed against the risks of prescribing antiseizure medications." jamanetwork.com/journals/jaman…

Going strong Doctors, £10 is a low price to watch the GMC face accountability for once If you can, donate ☠️

@clifford0584 Leave the employer. Any ED in Melbourne will be more than happy to hire you for 482. PM me and I will recommend few.

@xabahat Asked the employer who said no - hence why I’m asking

Has anyone on here navigated from 407 training visa into ACEM training and then to PR? Would be good to chat about your experience