🇨🇭 Swiss Society for Matrix Biology

📢 Registration and abstract submission for the #ECM2024 Congress opens in November 2023! @karsdal, Chair, reflects on the first event in 2022 and the upcoming congress. Program: ecm-congress.org @amsocmatbio @IntSocMatBio @ExtracellMatrix #ECM #conference #copenhagen

We built a "#Strategic outline of #interventions targeting #extracellular #matrix for promoting #healthy #longevity" #technologytree. 22'459 words & 557 references by @ParkisLaelaps @AaronLongevity @victorbjoerk @brad_w_e @alexanderfedintsev @AJPCellPhys doi.org/10.1152/ajpcel…

How does matrix stiffness impact transcriptional responses in #fibroblasts? In our (@SnedekerLab) latest work @AdvSciNews, “we show that elasticity approx. #tendon microscale stiffness (~35 kPa) reinstates tendon-specific transcriptional signature” (1/n) onlinelibrary.wiley.com/doi/10.1002/ad…

#Collagen constitutes about 12% in females and 17% in males of the #total #protein in mice! #rewriteTextBooks. See matreotype or ECM composition of entire mice. #matrisome nature.com/articles/s4159…

Many text books and publications state “#collagen is the most abundant protein making up 30% of total protein in mammals”. However, a direct measurement is missing. Here, we quantified total collagen of entire mice, which is 12-17%. biorxiv.org/content/10.110…

Free e-book on #ECM & #cancer edited by @KaramanosN @passi_alberto & @GotteProf! @GlycansC @IntSocMatBio @Matrixbiologie @SwissMatrixBio @MatrixBioANZ @ExtracellMatrix @MBIreland @BSMB1 @UK_Muenster @WWU_Muenster #proteoglycan #mmp #collagen #heparanase #syndecan #decorin

New publication by @PaulHiebert_ and colleagues @skintegrityCH identifies a novel role for the antioxidant transcription factor #NRF2 in regulating the #ECM. Great insight into the potential impact on #skin #aging! doi.org/10.1016/j.matb… @ETH_en @Unispital_USZ #dermatology

🚀Just launched! 📣New #CallForPapers -- The #ExtracellularMatrix and its Derived Effector Molecules in Aging: Regulators and Therapeutic Targets 📝We invite research on the ECM’s many biomechanical effects on #aging: ow.ly/krAT50L2BKI ▶️Guest Editor @CollinEwald

Super proud and happy for our @JNuchel for winning the prestigious Dick Heinegard Young Investigator Award! @IntSocMatBio @MPIAGE @Matrixbiologie @BCCologne @DemetriadesLab @DFG_FOR2722

@Matrixbiologie @JNuchel @IntSocMatBio @MPIAGE @BCCologne @DemetriadesLab @DFG_FOR2722 Congrats!

Great insights from #mechanical #tension to #calcium signaling via #piezo with #clinical implications for #aged and #injured #tendons by ⁦@SnedekerLab⁩ ⁦@ETH_en⁩ ⁦@SwissMatrixBio⁩ #mbe2022

Fascinating talk by @CollinEwald on #longevity, #collagen and #mechanotransduction! Lots to think about...(also never knew c elegans have 181 collagens!) #MBE2022 #ECMatrix

Full house to see @Vogel_Lab talk at the #MBE2022. #fibronectin under tension. #tumor #ECM @ETH_en @SwissMatrixBio

Forceful talk by ⁦@Amro_Hussien⁩ ⁦@SnedekerLab⁩ ⁦@ETH_en⁩ representing the ⁦@SwissMatrixBio⁩ for the #Heinegard award at the #MBE2022

Congrats to Paul Hiebert ⁦@WernerLabETH⁩ ⁦@ETH_en⁩ ⁦@SwissMatrixBio⁩ winning the Rupert Timpl award 2020 and was finally able to present at #mbe2022. #nrf2 #ecm #matrisome #aging #senescence

🧵 1/2 #chronicdisease often leads to #fibrosis. The @StockmannLab @UZH_en and colleagues developed an #immunotherapy that specifically targets the cause while leaving normal tissue cells unharmed. This could lead to an effective #treatment for fibrosis! doi.org/10.1016/j.stem…

In #Alzheimer's patient's brains, the #amyloid plagues are found within #collagens (#ECM). To study the interaction of ECM and amyloid beta, @JongsmaE built a novel in-vivo system to study amyloid beta aggregation and removal in the ECM. doi.org/10.1101/2022.0…

12 PhD studentships available to study ECM ageing @ECMage22 @BSMB1 @ECTS_soc @ExtracellMatrix @Matrixbiologie @MBIreland @SwissMatrixBio @UkAgeing @CIMA_Ageing For details, visit euraxess.ec.europa.eu/jobs/812870

@2022Pg @AJPCellPhysEIC @cfrevert @MerryLabNotts @MarissaMaciej @rjweiss86 @San_Gop @SwissMatrixBio @Glyco_Alps @BSMB1 @GlycoBioBoston @MBIreland @brookefarrugia @MatrixBioANZ @Matrixbiologie @ExtracellMatrix @DSMB_dk @GlycansC @IntSocMatBio

Deadline 5.7.22 For the Dick Heinegard Young Investigator Award, if you think you qualify to enter the competition via the @SwissMatrixBio to compete at the European Matrix Bio meeting. mbe2022.org Pls, DM here or @CollinEwald