Bubeck Lab
836 posts
@BubeckLab
Our lab adopts a structural biology approach to investigating the role of membrane proteins in host-pathogen interactions.
Exciting news! 🎉 BSPP's 2025 RKS Wood Prize has been awarded to Professor Paul Birch for his outstanding contributions to plant pathology. 🌿🔬 Learn more about his incredible achievements and this prestigious award here:📷buff.ly/4h95btp
Mind the GAP-New research alert!🚨Our latest study revealed the first known case of a pathogen effector targeting a RabGAP! 🦠The effector remodels the pathogen interface and suppresses defense-related secretion mediated by its cognate Rab.🌱🚦 #research biorxiv.org/content/10.110…
The γTuRC saga goes on! This time, we used cryoEM to describe how CDK5RAP2 helps nucleating microtubules by activating the γTuRC nucleator. Another tour de force led by @sernarina and Fabian Zimmermann and a fun collab with @LudersLab @IRBBarcelona. authors.elsevier.com/c/1jpyq_Yv6zvB…
🚨 A new twist in #NLRbiology! 🚨 Excited to report on the surprising mechanism where the helper NLR NRG1 targets organellar membranes to trigger immunity unlike canonical CC-NLRs, which function at the plasma membrane! 1/11 🧵 doi.org/10.1101/2024.0…
