Coralie Sengenès

MuSkLE Excellence Scholarships, offering outstanding Master’s and PhD students the opportunity to join a cutting-edge, research-driven graduate programme in Lyon (France): arqus-alliance.eu/news/apply-now…

cnrs.fr/fr/actualite/t…?

Un simple geste pour prolonger la chaîne humaine ✨️ 📸 Repartagez le dessin de #Lola Que son visage continue de se propager, de cœur en cœur 🤍✨️jusqu'à toucher toutes les âmes.

New Research Associate opportunity in nutrition and metabolism at @UniofBath funded by @BBSRC - closing date 20th August. Come and join @CNEM_Bath! bath.ac.uk/jobs/Vacancy.a…

Join us!

📢 #France2030 L’appel à projets (AAP) du programme de recherche exploratoire « Organes et organoïdes sur puces » (MED-OOC) est en ligne. 📅 Date limite de dépôts des dossiers : 27/05/2025 - 11:00 🔗 bit.ly/3XZtLVu

Interested in #cardiac_regeneration, #zebrafish, #aging, and the #immune_response? We are looking for a candidate to apply for a PhD opportunity from the CARe graduate school @CareGraduate in Toulouse!

We love to see everyone #StandUpForScience!

📢 #StandUpForScience Le 7 mars, mobilisons-nous en écho à l’action américaine Stand Up for Science ! 👉 standupforscience.fr

New! Online now: adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue dlvr.it/TJ5Z6K

scCamAge: A context-aware prediction engine for cellular age, aging-associated bioactivities, and morphometrics dlvr.it/THrNtj

Happy to share our work on the effects of neuromuscular electrical stimulation training on myonuclear accretion and hypertrophy rdcu.be/d8OoM Thanks @aurelief1624 @AZavoriti @BenChazaud and all the coauthors Funding @MyoNeurALP @Canceropol97501 @iNeuroMyoGene

I was surprised to hear @DoctorChrisVT say “the whole idea that you can burn more calories by doing exercise was funded, if not by Coca Cola, then by the soft drinks industry” youtube.com/watch?v=j1oOoY… Is this true? 👇 @Ri_Science Cc @theproof @NutritionMadeS3 @GilesYeo

It was an absolute dream to help with this Method of the Year! SPATIAL PROTEOMICS gets a well-deserved spotlight! Thanks so much to all the authors who contributed their comments! @RongFan8 @BodenmillerLab @leeat_keren @labs_mann @DanielaQuail

If we look at thousands of proteins (i.e., signals) in the human blood, the protein most associated with chronic physical and mental illnesses is the **same protein** as the top marker for mitochondrial diseases: GDF15 When mitochondria cannot flux energy properly, the cell makes and secretes GDF15 in the blood to alert other cells Some highlight by Cynthia Liu in our group: - GDF15 is the top predictor for most diseases - GDF15 associated with diabetes is among the most significant protein-prevalent disease associations Based on p-value, GDF15 was most significantly associated with disease. - “GDF15 was associated with the most diseases, containing 205 prevalent and 397 incident diseases, generally acting as a risk factor except for three incident diseases (respiratory diseases affecting the interstitium, disorders of magnesium metabolism, and peripheral artery disease).” - “GDF15, similar to its high ranking with protein-disease pleiotropy, ranked second for protein-trait associations, boasting a substantial 428 associations.”Significant associations with many lipid metabolite markers. - Mental disorders like anxiety disorders, depression, and mood disorders, along with mental health-related traits, also exhibited substantial proteomic signatures including elevated GDF15 - “The fluid intelligence score and various types of dementia shared significant proteins such as NEFL and GDF15 (Figure 2G)” - “GDF15, the protein with pleiotropic effects, was causally associated with several autoimmune diseases, including ulcerative colitis and rheumatoid arthritis (Figure 6B).” Data from >53,000 people in the UK Biobank Full paper here: cell.com/cell/fulltext/… Resource to explore your favorite protein or disease/trait of interest: proteome-phenome-atlas.com

Lucky you! Fantastic! @isaperarnau

Yaaaa!!!

Elena won the oral communication prize of the #JSFM2024 days! We are super proud of her! Those muscle days were really cool! See you next year in Aix les Bains!!!

SAVE THE DATE! Fourth edition of MuSkLE Summer School We welcome Bachelor (in priority) and Master students on June 1-6, 2025. Infos and registration: muskle.univ-lyon1.fr Keynote speakers are coming soon. @UnivLyon1 @ENSdeLyon @Univ_St_Etienne