Kim Reiss Binder (Kim Reiss)

Updates ph1 INCB161734 KRAS G12Di #PDAC #GI26 ➡️ sel On/Off, n=61 mono (1200mg) n=44 combo ➡️ORR mono 37% (n=41) ➡️ ctDNA 66% on 1200mg molecular response (≥90% reduction) ➡️ tolerated with GnP and mFFX (data on n=23) ➡️ KRAS CN - ‼️resistance @ASCO @myESMO @OncoAlert

🚨 We have two ongoing maintenance trials for patients with pancreatic cancer and at least stable disease after 4-6mo of chemo. FFX or G/A, mPDAC or LAPC. If your patient needs a chemo break, send me a DM! @PennMedicine

After being diagnosed with #PancreaticCancer, Steven Merlin found hope through a #clinicaltrial. Now as an @eaonc advocate, he shares his perspective on the benefits of clinical trials. Read his inspiring story: bit.ly/beatingtheodds… cc: @letswinpc, @PanCAN, @SeenaMagowitz

@s86CoffeeDev @Aiims1742 @EladSharonMD Nailed it

@Aiims1742 @EladSharonMD @KReissMD Say what yer gonna say Say it Say what you said

New strategy I just learned from @KReissMD - start your talk with the take home messages first. Have to work this in….

@Aiims1742 I stole the idea from @ASCO ! It was their suggestion for Education Sessions. Can’t claim credit (though would love to!).

@Ron_cology Harder to fit on a hat! 🤣

@KReissMD Good but not as good as YCKMMF…

From one of my most fabulous patients. #fuckcancer

Hazel the Chicken Gets Eggstra Help is officially on the shelves at two of our local bookstores! @MainPoint_Books and Character Development! Thanks to everyone who has supported - we really hope this book will make a positive impact on kids. #kidlit

Do you have #PancreaticCancer with a BRCA1, BRCA2, or PALB2 mutation and resected (surgically removed) pancreatic cancer? If so, you may be able to participate in this study of a potential new treatment. Learn more: bit.ly/apollo-trial cc: @KReissMD

@CentralParkWMD @anup_kasi @Aiims1742 @EileenMOReilly The amazing @TimothyJBrownMD just enrolled another patient!! Super⭐️

@anup_kasi @Aiims1742 @KReissMD Let’s think about this study!! ☝️#APOLLO @KReissMD @EileenMOReilly @anup_kasi

Novel insights & therapies for BRCA-related #PancreaticCancer 🔬 @KReissMD gave an amazing talk remotely! - we missed you in person! #AACRPan25 Consider BRCA1/2, PALB2, RAD50, RAD51 for adjuvant #APOLLO. Kim leading the way w translational work & PARP1i. #POLO #POLAR #PancSM

You may be eligible to participate in a #PancreaticCancer study, EA2192/APOLLO, for patients with #PancreaticCancer that has been surgically removed and has a BRCA1, BRCA2, or PALB2 mutation. Learn more: bit.ly/apollo-trial #pancsm cc: @KReissMD

@CentralParkWMD Missed seeing you! Having so much FOMO over here

Learn about the EA2192/APOLLO study, treating patients with #PancreaticCancer that has been surgically removed and has a BRCA1, BRCA2, or PALB2 mutation. More information: bit.ly/apollo-trial #pancsm #pancaware cc: @KReissMD

Congrats to the authors. The impact is high. Aspirin 160mg daily for CRC secondary prevention if PI3K (+), the risk becomes half!

Putting out the 🦇signal for #EA2192 (APOLLO). 97/152 patients enrolled! Pts with BRCA or PALB2 who have completed curative intent tx for PDAC within the last 3mo are eligible. 🎯💊 @eaonc @EileenMOReilly @BasserBRCA @FacingOurRisk @anup_kasi @letswinpc

@Aiims1742 Nice!

@KReissMD Ha! They read your mind - see middle arm in RASOLUTE 303 (6 months of chemo combo then switch maintenance to monotherapy)

Revolution Medicines Daraxonrasib data in first line metastatic #PancreaticCancer - monotherapy & combination with Gemcitabine nab-paclitaxel. Even monotherapy ORRs and DCRs are impressive! Do you need the chemo? Grade 3 AEs go from 35% to 58%. RASOLUTE 303 will answer.

Please don't forget. Last day to submit ASCO GI #GI26 abstracts is September 9. Also, senior investigators, please remember the place of honor for you is last author. First author is for people developing their careers.

@The_Pigeon would you read this book? You do often seem to need extra help…🤔

For every kiddo who has felt a little different in the classroom, @BKaplan12 and I co-wrote this book to help them know it’s ok to need some extra help! Illustrated by Avery Stern. @IngramPubPros @MoWillems #HazeltheChicken #SpEd #speced #childrensbooks