Shaylon Sharp
10.1K posts
@ShaylonSharp
Troubadour. Friend of Dogs. Smoker of Meat. Philosophy, History, Theology. Fan of Western Civilization. MDiv. Soli Deo Gloria. Roll Tide 🏈🐘
I will judge you based on your opinion of this man
David Sinclair's lab is using AI to build a pill that reverses aging for $100. Right now, their gene therapy costs roughly $10 million to manufacture. It requires a direct injection into the target organ. That's not going to work for 8 billion people. So Sinclair's team made a breakthrough. They found that the three age-reversal genes aren't the only path to resetting cells. They discovered CHEMICALS that do the same thing. In mice, they can now give an animal a liquid — not genes, not injections, a drink — and rejuvenate tissues in 4 weeks. Sinclair says it's now normal for his students to casually report: "We just rejuvenated the ear. We just rejuvenated the skin. We just cured ALS (motorneuron disease) in these animals." He calls his lab "Willy Wonka's chocolate factory" because the discoveries blow him away every week. But he wants one molecule that does everything. So they used AI to screen 8 BILLION candidates. They're now down to three molecules that work. And they're using AI to try to combine all three into one. The gene therapy could cost over $100,000 per treatment. Sinclair's goal: "What if it could be $100 instead? That's what I'm working for. I want to democratize this technology so anyone even in Kenya can take these medicines." They should know within a year or two if the molecules work in mice. The gene therapy is the proof of concept. The pill is the endgame. — @davidasinclair
In honor of Tolkien Reading Day and the destruction of the One Ring, we bring you a special announcement.
NEW 'LORD OF THE RINGS' MOVIE Stephen Colbert is co-writing "The Lord of the Rings: Shadow of the Past" (working title), which will go into production after "The Hunt for Gollum." The synopsis: "Fourteen years after the passing of Frodo - Sam, Merry, and Pippin set out to retrace the first steps of their adventure. Meanwhile, Sam’s daughter, Elanor, has discovered a long-buried secret and is determined to uncover why the War of the Ring was very nearly lost before it even began." Colbert is co-writing the script with his son, Peter McGee, and franchise veteran Philippa Boyens. variety.com/2026/film/news…
There’s just not a lot of guys in the country that can make this throw…. Someone’s going to be lucky to get Ty Simpson
