TambarLab

Our lab recently discussed the research career of our good friend Neil Garg @GargLab @uclachem @UCLA. What’s your favorite paper from the Garg Lab? Here are some papers selected by us: pubs.acs.org/doi/10.1021/ja… pubs.acs.org/doi/full/10.10… nature.com/articles/nchem…

Check out this cool cascade oxidative trifluorination and halogenative cyclization of tryptamine-derived isocyanides, which was recently reported by Honggen Wang and Qingjiang Li. Do you know the mechanism?

Check out our review in @JournalCancer on recent advances in targeting HIF‐2 in renal cell carcinoma, with a focus on belzutifan. Academic labs can have a tangible impact on the treatment of cancer patients. @AmericanCancer @utswcancer @UTSWMedCenter acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn…

Check out our recent paper in @ChemCatalysis on the photocatalytic three-component carbonyl alkylative amination. This reaction couples aldehydes, anilines, and alkyl arenes via direct C–H functionalization. cell.com/chem-catalysis…

Happy Holidays and Happy New Year from the Tambar Lab! Enjoy our Famous Chemists of the Week from 2025!

Happy Holidays and Happy New Year from the Tambar Lab! Enjoy our Mechanism Problems from 2025!

Our lab discussed the impactful research of Seth Herzon @HerzonLab @YaleChem. What’s your favorite Herzon paper? Here are some papers selected by our lab: pubs.acs.org/doi/10.1021/ja… pubs.acs.org/doi/10.1021/jo… pubs.acs.org/doi/10.1021/ja… science.org/doi/10.1126/sc… pubs.rsc.org/en/content/art…

Xihe Bi from Northeast Normal University reported this beautiful cyclization of 4-ynamides into dihydrofuran-2(3H)-ones What’s the mechanism? Mechanism by grad student Lauren Duncan.

Professor Karen Erickson @ClarkUniversity reported a beautiful rearrangement of (halomethylene)cycloalkanes. Let us know if you have any ideas for this insane mechanism! And let us know if you have a picture of Professor Erickson. Mechanism by grad student Rene Garcia Del Valle.

Happy birthday to grad students Thor Peterson and Jordan Martinez!

Lorena Saelices, Ph.D., and Uttam Tambar, Ph.D., are this year’s Biotech+ at Pegasus Park Milestone Award recipients for advancing an early preeclampsia test and a new therapy for drug-resistant prostate cancer. Learn more: bit.ly/482Gr2b #ScienceInAction #Biotech

Congratulations to our 2019 #HackermanAwardee @UttamTambar for winning a @UTSWMedCenter Milestone Award! The @TambarLab demonstrates how targeted glucocorticoid receptor (GR) degraders combats metastatic prostate cancer by eliminating drug-resistant proteins. tinyurl.com/4xtudej9

Our lab recently discussed the impactful research of Stephen Buchwald @ChemistryMIT. What’s your favorite Buchwald paper? Here are some papers selected by our lab: onlinelibrary.wiley.com/doi/10.1002/an… pubs.rsc.org/en/content/art… pubs.acs.org/doi/10.1021/ja… science.org/doi/10.1126/sc…

TexSyn-VII will be held May 29-30, 2026 at UT Dallas. Come see great synthetic chemistry from the Lone Star State, y’all! texsyn.org

Happy birthday to grad student Tiffany Brisco @Tiffany05Brisco !

Thank you MilliporeSigma @MilliporeSigma for sponsoring another successful Aldrich-UTSW Excellence in Chemistry Symposium! We heard great seminars from Dean Toste @UCBerkeley, Mike Taylor @uarizona, Andrew Morrow (Smith Lab), and Nate Schmitt (Tambar Lab) @callmefortuNate

Congratulations grad student Nate Schmitt @callmefortuNate on successfully defending your PhD thesis! We are very proud of you. You will be missed. @UTSWGradSchool @UTSWScience @UTSWMedCenter

pubs.acs.org/doi/10.1021/ja… onlinelibrary.wiley.com/doi/10.1002/an… science.org/doi/10.1126/sc… pubs.acs.org/doi/10.1021/ac… sciencedirect.com/science/articl… nature.com/articles/s4157…

Our lab recently discussed the impactful research of our friend Richmond Sarpong @SarpongGroup @UCBerkeley. What’s your favorite paper from Sarpong’s Lab? Here are some papers selected by our lab...