Edgar Pinedo-Carpio

Free scientific illustrations for biologists! 😍 @NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov

FANCI that! New #LMSResearch from @RuedaLab has solved the decades long mystery of how DNA damage by sunlight, alcohol and pollution is identified so it can be repaired. This discovery opens up opportunities for improved cancer treatments. lms.mrc.ac.uk/fanci-that-dec…

Excited to launch our cloud-based image analysis platform today at nimbusimage.org! Analyze and interact with your data, all in the browser. Follow sign-up instructions to request an account.

@elonmuskADO Twitter

How did humans loose our tails? ~25 million years ago, a monkey in Africa had a random mutation due to transposable elements (TEs) - pieces of DNA that can copy themselves in the human genome. An Alu element was inserted into the intron of the TBXT gene, producing alternative transcripts lacking the 6th exon. This is due to pairing with another Alu element in the other side of the 6th exon. This mutation is only observed in hominoids without tails: gibbons, gorilla, chimps. Their common ancestors can be traced to that one monkey-like animal 25 million years ago. Introducing this mutation to mouse results in complete loss of the tail. Congrats @ItaiYanai Read this week's cover story of Nature. nature.com/articles/s4158…

Only one team could progress to the next round... 🇯🇵🇸🇳 #BeachSoccerWC

We are thrilled to share our study on the role of cellular #senescence in #diabetic macular edema and clinical data for the first #senolytic developed for the eye . Congrats @SerCresGar and @UnityBiotech! @UMontreal @NatureMedicine @CellSenResearch nature.com/articles/s4159…

Excited to share our recent study in @CellCellPress led by @GiuseppeLeuzzi_ on the dual role of the DNA translocase SMARCAL1 in regulating innate immune signaling and the expression of the PD-L1 immune checkpoint factor! authors.elsevier.com/a/1iWe5L7PXqPXc

On a scale of 1-10, 10 being perfect, I have to award this eagle with a 12. 😃 If you ever wanted to see a perfect example of an eagle’s ability to fly, grab a fish and eat it in mid air, I think this is it. What would you give this eagle on a scale of 1-10?

Excited to share: "CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue". We applied our novel approach in wonderful collaborations with @CicciaAlberto, @DrEdmondChan, @elhamazizi, and @landau_lab. biorxiv.org/content/10.110…

I was watching Lord of the Rings last night and realized there are many parallels with academia! A thread 🧵👇

@soccergoalie67 @SebMarinMD @LoveThePlateau France's tuition fees for international undergrad students: €2,770 Euros per year, €3,770 for postgrad study and €380 Euros per year for a PhD. Non-EU PhD candidates are not subject to new differentiated tuition fees. But QC thinks FR is giving them a preferential rate 🙄

@SebMarinMD @LoveThePlateau There are many more French students that benefit from this agreement than Quebec students. Once again showing that the government here will bend over to appease their so called French counterparts

Wow. Wow. Wow. Incredible powerful message (incredible speech writing)—to those who stumbled on the wrong path and may ruin their future for not knowing the past. The weight of history

Immensely proud to share our four papers on #SingleCell dissection of #Alzheimers Disease coming out in @CellCellPress today, reporting 2.3M #scRNA profiles and 850k #scATAC profiles across 427 post-mortem human brain samples from AD and non-AD donors in a wonderful #interdisciplinary collaboration with @DrLiHueiTsai between @MIT @MIT_Picower @MIT_CSAIL @BroadInstitute @RushUniversity Paper 1: scRNA + vulnerability + resilience cell.com/cell/fulltext/… Paper 2: scATAC + GWAS + Epigenome Erosion cell.com/cell/fulltext/… Paper 3: Microglia States + reprogramming cell.com/cell/fulltext/… Paper 4: DNA damage + gene fusions cell.com/cell/fulltext/… MIT News: news.mit.edu/2023/decoding-… Issue: cell.com/cell/current News & Views: cell.com/cell/fulltext/…

Genes associated with autism and other neurodevelopmental disorders are identified using CRISPR screening in human forebrain assembloids. #NBThighlight nature.com/articles/s4158…

Svetlana Mojsov helped discover the hormone GLP-1, which led to the development of blockbuster obesity drugs. Now, she’s fighting for recognition. #LongReads scim.ag/45z @NewsfromScience

@CarlosMendezPhD Thanks Carlos!! You advice was always appreciated 😉

Congratulations @lymphocytePC !!

@DessaptJ Congrats brother, very proud of this story and all the amazing teamwork that led to this publication. I FIRRMly believe that we are going to hear a lot about this novel protein and its partners.

Excited to see my first (co) first author paper go out and to share the results of all the work provided over the last two years to understand C1orf112/FIRRM role in DDR! Congrats @lymphocytePC and everyone else involved!

We are very excited to share with you the results of great teamwork with @AmelieFT lab! In this study, two graduate students @lymphocytePC and @DessaptJcharacterized the critical role of FIRRM/C1orf112 in the disassembly of RAD51 during DNA repair. science.org/doi/full/10.11…

Today we report in @ScienceMagazine a one-time base editing treatment for Spinal Muscular Atrophy (SMA), the leading genetic cause of infant mortality worldwide, affecting ~1 in 10,000 births. science.org/doi/10.1126/sc… PDF: drive.google.com/file/d/1H1k8AA… 1/17