no

@caloriesproper2 idk why people don't grasp this one

Wrong. Backwards. Circadian health is *more important* in the modern environment than it was in the past.

@kobladoura93874 @EylonALevy aye

@nullbotto @EylonALevy aye, and you?

Not another one

@oteycoueye medicine wheel shape store

Idea: Wyoming spiritual retreat called Homeless Mountain. Dose the homeless with industrial quantities of mescaline, set them loose in the Bob Marshall Wilderness. They might meet Manitou. Or whatever.

@JoshRainerGold covfefe with milk and salt is epic

I always get such crazy salt cravings on milk diet

Nobody guessed

@Rafahsuckzblood @oteycoueye it's genetic

@oteycoueye Shitting entirely liquid like a firehose and then going immediately back to the next footlong

Goy Bowel Syndrome

@oteycoueye yidda u KNOW I can't be having any semites in this hood

It's not that I personally have anything against the Jews, it's that I'm worried they'll attract antisemites

@PatrickHeizer the kaffir lime bergamot icon in the op tho

A real slide from one of my journal clubs:

@oteycoueye @Rafahsuckzblood Regular as in it happens more than once a week

@Rafahsuckzblood They can pray in the REGULAR minyan if they're discreet about it

A literal sundown minyan! "Frenkim, don't let shkiah set on your brown asses in this minyan."

@TakeThiamine CR: "Similar to the outcome of the first rhesus monkey trial, many reports of lifespan extension in rodents could be due to the experimental conditions with ad libitum-overfed control mice" "leading >40% of the control animals to develop diabetes" journals.physiology.org/doi/full/10.11…

A man restricted calories for three decades, with low intake of saturated fat and animal protein. End result: died of a neurodegenerative disease involving lipid peroxidation. What causes lipid peroxidation. Why is it cytotoxic? Why didn’t his lifestyle protect against this?

@TheFelixArnold @BigolWave nope

@BigolWave saturated fat causes liver disease

Saturated fat protects the liver and even reverses liver disease btw

@Iris_Illera no more tin please

Idea: you don't fucking use molten tin and just use high-harmonic generation like living people with cultured fetishes.

@LawrenceElliots @exfatloss Most those "hormetic stressors" are those you can expect to get future chronic stress similar to it. Not really all that beneficial. Caloric restriction is also fake and unhelpful if you aren't eating shlahp.

@exfatloss And neither are any of the stressors we benefit from?

Why aren’t we sleep fasting? Since periodically restricting my sleep, I have trained myself to function (better) on less I used to require 7-8 hours. I am now outperforming on 5-6. Contrast therapy - accepted. Fasting - accepted. HIIT - accepted. Deliberate sleep restriction - never discussed. Hormesis applies universally across every biological system (except the one the wellness industry monetises most aggressively) The pattern across all hormetic interventions is identical: 1. controlled acute stress 2. recovery 3. supercompensation. We know: - The dose makes the poison. - The recovery makes the adaptation. (This is not controversial in any domain except sleep) What else do we know? Sleep deprivation triggers BDNF upregulation. (Brain-derived neurotrophic factor - The same molecule everyone celebrates when discussing exercise, meditation, and learning). Drummond's imaging data shows the brain recruiting compensatory networks under sleep debt - Parietal regions dormant during comfortable, well-rested cognition suddenly activate. Periodic sleep fasting, employed strategically + paired with proper recovery, accesses adaptive mechanisms that build resilience. (Resilience that 8 hour regularity cannot achieve) We’ll see how long it takes Huberman and the like to catch on

@kobladoura93874 @EylonALevy u aright lad?

@EylonALevy You are a liar! Israhell is winning, Donald and Deadanyahu said it from hell. Try being a pro-Israel unpaid influencer. They show every day how chilled things are in the occupied lands

@oteycoueye @EylonALevy Chungachung chung chung

@EylonALevy Shut up, Eylon, you miserable whining Hasbarite.

@CommunityNotes this is wrang

@stannieholt @annesheraton @baym @fulop_dan That's not Bergamot. That toad look is kaffir lime.

@nullbotto @annesheraton @baym @fulop_dan Bergamot can be either green or yellow and looks like this: pura.com/blogs/pura/the…

Modern bio can only dream of tech as deep as citrus

if it ever gets this bad, old yeller me

@DenialLaw Benjis Khan

when people tell you who they are listen