JonesLabUCSF

Thank you @agingdoc1 for sharing! I’m so proud of what we’ve built @UCSFaging and look forward to more advances in geroscience together!

What an inspiring week at #JPM2026! It was energizing to connect with so many innovators pushing the frontiers of healthy aging. From all of us at BARI, thank you, stay safe on your journeys home, and see you soon!

How do Arctic ground squirrels thrive in extreme hypoxia? BARI member Dengke Ma and his team reveal in @emboreports conserved downregulation of triglycerides boosts resilience to low oxygen & aging, protecting mitochondria & extending lifespan. bit.ly/3NKhiCE

Congrats to BARI’s Tien Peng on this groundbreaking study in @CellStemCell! Identifying senolytic-sensitive fibroblasts that rewire lung cancer metabolism opens new doors for targeting aggressive tumors. A major step in cancer & aging research. Read more: bit.ly/3L7ATfr

Research from @ishahjain and colleagues published in @CellCellPress shows that HypoxyStat, can prevent or reverse #mitochondrial disease in a preclinical mouse model. bit.ly/4kh0csc

“It’s a paradigm shift to know that the silent X doesn’t stay asleep,” says Dena Dubal, a neuroscientist and neurologist at the University of California School of Medicine in San Francisco, who led the study. go.nature.com/3Di2d6K

Have you seen the latest @Nature Index Ratings for Aging research in 2025? BARI’s innovations helped propel @UCSF to #2 globally! Incredibly grateful for our collaborators working with us to push boundaries against age-related decline. Full list here: bit.ly/4aInvZq

Exciting breakthrough in Parkinson’s research! BARI scientist Ken Nakamura and lab show in @ScienceAdvances how CHCHD2 mutation-induced mitochondrial dysfunction in DA neurons leads to α-synuclein aggregation in vivo. #Parkinsons #Neuroscience bit.ly/4aWt4n4

Congrats to BARI postdoc Jarin Tusnim (Piao Lab), on securing Cure Alzheimer’s Fund award! Jarin investigates how ADGRG1 enables microglia to protect against tau spreading, unlocking new ways to boost microglial resilience and target therapies for AD. Proud of our BARI talent!

Congrats to our fellow @UCSF aging scientist Lauren Hunt on receiving the 2025 Terrie Fox Wetle Rising Star Award from @AFARorg! Her vital research on palliative care for older adults with dementia is transforming aging health services. BARI celebrates this well-deserved honor!

Have you had a chance to check out BARI’s Xian Piao and her team’s paper in @NeuronJournal? They show how microglial ADGRG1 activates MYC to drive protective responses against Alzheimer’s – boosting phagocytosis & reducing amyloid. A major step forward in AD research! #Alzheimers

In case you missed it: BARI researcher John Greenland and team show frailty in lung transplant recipients links to shorter telomeres and anemia, but not epigenetic age or inflammation. Selective aging hallmarks at play! #Frailty #Transplant amjtransplant.org/action/showPdf…

1/ Can we find more precise and even safer ways to rejuvenate vision? As a step towards this goal, I am excited to share this preprint of my 1st postdoc work from @JswLab with amazing collaborators, esp. @Bruce_Ksander! Using functional genomics, we discovered GSTA4 as a key OSK effector for oxidative resilience—overexpressing it alone rejuvenates RPE & restores vision. A breakdown👇biorxiv.org/content/10.110…

📢 Last chance to register! There's still time to sign up for the FUSION Stem Cells and Cancer Conference 🗓️ Registration closes on 31st July bit.ly/49sCfJp Co-chairs @JonesLabUCSF @PlathLab @KateMiro1

@JonesLabUCSF @PlathLab @MariaPAlcolea @KateMiro1 Please share! @BrainSurgn1989 @CedricBlanpain @HiroFujiwara @MRSantosLab @telomerase2 @AndreaSottoriva @leonard_zon 🇲🇹🌞

Come join us in Malta to dive into #Stemcells and #Cancer! In addition to an outstanding line up of speakers, we will have talks chosen from abstracts, as well as travel awards for early career investigators!! 👩‍🔬👨‍🔬

SAVE THE DATE! 📅 The Stem Cells and Cancer Conference will take place 28 Sept – 01 Oct 2025 in St Julians, Malta! 🇲🇹 Join @JonesLabUCSF, @PlathLab, @MariaPAlcolea & @KateMiro1 for this continuation of the GRC 'Stem Cells and Cancer' series. For more information & to register ➡️ bit.ly/49sCfJp

Do you want to grow 3D epithelia ex vivo long-term (~1 year) without passaging them? Check out epitheliods! nature.com/articles/s4158… Excited to have shared the journey with two great scientists @AlbertHerms and @AntoranLab and the Phil Jones' team. Image credit to @MTBejar.

We’re hiring! I have moved my #systemsbiology of #aging Drosophila lab to @HNRCA_Tufts in the heart of #Boston. We are looking for a research technician to join our team. Recent college grads or those with more experience all welcome to apply. jobs.tufts.edu/jobs/20934?lan…

Conference on biology of #aging: Take advantage of the early bird registration fee until September 30. Learn more and register today: hubs.li/Q02CqsCz0 @CellCellPress @ImmunityCP @Cancer_Cell @Westlake_Uni