KleinerLab

155 posts

KleinerLab

KleinerLab

@KleinerLabRNA

The Kleiner lab investigates the chemical biology of RNA modifications and their role in gene expression regulation. https://t.co/qic269Hicm

Sumali Eylül 2021
457 Sinusundan747 Mga Tagasunod
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The Muir Lab
The Muir Lab@MuirLab·
The final version of our protein transposition manuscript is now published in @ScienceMagazine science.org/doi/10.1126/sc… We’ve added a few new things since our preprint /1
The Muir Lab@MuirLab

Ever wanted to swap out an entire internal region of a folded protein for functional biochemical studies? Check out our preprint that has been 5 years in the making, in which we establish a protein editing platform via protein transposition, enabling the insertion of functional cargo or PTMs into internal folded protein regions. #proteinengineering #proteinediting biorxiv.org/content/10.110…

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Josh Riback
Josh Riback@SuperSciJew·
In lab's #FIRSTPREPRINT, we present methods to measure nanometer organization around & between specific proteins in condensates. We uncover unexpected heterogeneity for a liquid-like phase with local meshwork spanning 10-50nm, stemming from ribosome biogenesis in the nucleolus.
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bioRxiv Biophysics@biorxiv_biophys

Nanometer condensate organization in live cells derived from partitioning measurements biorxiv.org/content/10.110… #biorxiv_biophys

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KleinerLab
KleinerLab@KleinerLabRNA·
We are looking for a postdoc candidate in RNA chemical biology, broadly defined. Interested applicants can email me at rkleiner@princeton.edu with their CV, research summary, and names of 3 references. kleiner.princeton.edu
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KleinerLab
KleinerLab@KleinerLabRNA·
@Yael_David__ @CellCellPress A little late to the party but congrats on this exciting work! I remember you sharing some of it with me a few years back.
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Yael David
Yael David@Yael_David__·
I am extremely proud to see our work about Hepatitis B now published in @CellCellPress. From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵 cell.com/cell/fulltext/…
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Brian Liau
Brian Liau@brian_b_liau·
Today in @Nature we share our back-to-back stories with @nzhenguw revealing chemical-genetic convergence between a molecular glue & E3 ligase cancer mutations. 1/6
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Princeton Chemistry
Princeton Chemistry@PrincetonChem·
Congratulations to Qais Jaber, awarded a two-year @EMBO Postdoctoral Fellowship supporting excellent postdoc research. Qais will continue his work in the @KleinerLabRNA deciphering RNA modifications in pathogenic bacteria.
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Brian Liau
Brian Liau@brian_b_liau·
Incredibly honored to receive this prestigious recognition on behalf of @liaulab, a reflection of their creativity, brilliance & hard work. They’re a super talented & fun group that I’m so lucky to work with. Also very thankful to my mentors. Still need to pinch myself every day!
ACS Biochem and ChemBio@acsbiol

Congratulations to @brian_b_liau of @HarvardCCB on receiving the 2025 Eli Lilly Award in Biological Chemistry for developing innovative approaches to #genomeediting using #chemicalbiology tools!

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Keriann Backus
Keriann Backus@Keribackus·
Bit of good news to end the week---and a big big thank you to everyone who helped make this possible, especially all members of our lab past and present, mentors, letter writers, colleagues, friends+family.
UCLA Biological Chemistry@BC_UCLA

We are thrilled to announce that @Keribackus has been promoted to the rank of Associate Professor with tenure! We congratulate Keri on this well-deserved achievement and look forward to her lab continuing to make impactful discoveries! 👏👏🎉🍾

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Jay Schneekloth
Jay Schneekloth@jschneek·
An honor to announce our book has been published! Many thanks to Martin Pettersson, the team at Wiley, and all our amazing contributors for making this exciting project happen! onlinelibrary.wiley.com/doi/book/10.10…
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Princeton Chemistry
Princeton Chemistry@PrincetonChem·
We are just opening the summer Visiting Faculty Research Partnership season and are thrilled to be hosting, among others, the Graham Chakafana Lab of @_HamptonU. The lab will be doing malaria research hosted by the @KleinerLabRNA. This marks their 2nd summer @PrincetonChem!
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KleinerLab@KleinerLabRNA·
I'm very excited to share the news of my promotion. Much of the credit goes to the trainees that drove the research forward, and the invaluable mentorship that I received along the way from Michael Hecht, @davidrliu, @KapoorLab_RU, my Princeton colleagues, and many others!
Princeton Chemistry@PrincetonChem

We are so very pleased to announce that @PrincetonChem’s Ralph Kleiner has been promoted to Associate Professor with tenure. Congratulations Ralph and the @KleinerLabRNA! Story here: bit.ly/4bJ4NhZ

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Tuklasin

@LindsayABecker @sofiquinodoz @david_a_knowles @ScienceMagazine @Yael_David__ @CellCellPress @brian_b_liau @Nature