PCF_SELECT
369 posts
@PCF_select
Multidisciplinary team working together to develop, validate, and implement liquid biopsies to improve the lives of patients with prostate cancer.
Exploring the biology of metastatic hormone-sensitive #ProstateCancer: on the road to precision medicine In this Review, Alice Bernard-Tessier & Himisha Beltran @mishabeltran @danafarber discuss the underlying biology in mHSPC and highlight current knowledge gaps: doi.org/10.1172/JCI200…
New research published in @NatureComms provides critical mechanistic insights into how prostate cancer becomes resistant to treatment, uncovering how two key epigenetic mechanisms - DNA methylation and EZH2 activity - work together to drive transformation to a more aggressive form of the disease, neuroendocrine prostate cancer. @DanaFarber @bajji @mishabeltran Read more: bit.ly/4sk61bg
@doldivizio is the lead PI on the NCI grant ‘Phenotyping Large #Oncosomes for Ultimate Evaluation of Patients Status’ (PLUS) to develop a #prostatecancer liquid biopsy assay with co-PIs @FrancescaBZNY & @svploeg. Congratulations Dr. Di Vizio & team! @theNCI
🚨 New Preprint Alert! 🚨 I’m thrilled to share our latest study now online on JCI: CRISPR/Cas9 screens identify LIG1 as a sensitizer of PARP inhibitors in castration-resistant prostate cancer. 🔬 Check out the preprint here: doi.org/10.1172/JCI179… Huge thanks to @FrancescaBZNY, @FraLo05, all Demichelis’ lab members and facilities staff at @UniTrento @CIBIO_UniTrento, and key collaborators @quimmateo, @FdAdF66 and Helmut Klocker. Special thanks to Fondazione Trentina per la Ricerca sui Tumori, @AIRC_it fellowship, @ERC_Research, @PCF_Science, and MIUR. #ProstateCancer #CRPC #LIG1 #PARPi #Biomarker #SyntheticLethality #PrecisionMedicine
A man who deserved the two standing ovations regardless of his own cancer journey. @felixfengmd: “I just want to thank my friends” and “Behind every clinical trial is a patient like me. Thank you.” #PCFRetreat24
Tonight we sit with the cherished memories of a truly unforgettable individual who changed the lives of so many fighting cancer. Tomorrow we stand and get back to the fight against the terrible disease that took one of our best, brightest, and kindest. Love you forever, Felix.
Felix was the best of us. I'm heartbroken by his passing.💔His spirit of generosity, kindness, humility, his humor, intelligence & scientific acumen - you made us better scientists & better people, Felix. Love & miss you always. My deepest condolences to @MaryFengMD & family.🙏♥️
Tonight we sit with the cherished memories of a truly unforgettable individual who changed the lives of so many fighting cancer. Tomorrow we stand and get back to the fight against the terrible disease that took one of our best, brightest, and kindest. Love you forever, Felix.
