Americrusader

@bryan_johnson Bryan these gh analogues down regulate your natural gh and igf-1 production and don’t work very well either. Better off just using hgh replacement or raising levels naturally which you probably already know.

Just spent over an hour with my clinical team debating which growth hormone peptide protocol to run. Still torn. Wanted to share the thinking and get your take. The goal: Increase GH and IGF-1 to support anabolism, recovery, and sleep, but also test a specific stacking hypothesis. Tirzepatide (GLP-1/GIP agonist) can elevate resting heart rate, disrupt sleep, and suppress appetite aggressively. CJC-1295 (GHRH analog) can worsen insulin resistance. The bet is that combining them cancels each other's downsides: CJC-1295's slow-wave sleep enhancement offsets tirzepatide's sleep disruption, while tirzepatide's insulin-sensitizing effects counteract CJC-1295's insulin resistance. Best of both worlds — or at least, that's the hypothesis we're testing. The two candidates: CJC-1295 with DAC: the long acting version. One injection per week, stays active for 6–8 days. This is what was used in the actual clinical trials. Raises GH 2–10x and IGF-1 1.5–3x from a single dose. Preserves GH pulsatility even under continuous stimulation. The tradeoff: if you get side effects, you're committed for a week. Harder to titrate. CJC-1295 without DAC + ipamorelin: the short-acting version paired with a selective ghrelin receptor agonist. Daily injections, pre-bed, clears in 30 minutes. Ipamorelin adds a second axis of GH release, pulse frequency via the ghrelin pathway, on top of the amplitude boost from CJC. No cortisol or prolactin elevation. This is what most clinicians prescribe and most of the peptide community uses. The tradeoff: less clinical trial data, daily injections, more anecdotal evidence base. What we're considering: Start with DAC at half dose 2.4 mg, then if well tolerated escalate 4.8 mg, weekly injection. If side effects aren't tolerable, switch to no-DAC + ipamorelin (100 mcg then 200-300 mcg daily, before bedtime). Or, Run both head to head. 2 weeks DAC, 2 weeks no-DAC + ipamorelin and compare. Tracking: GH, IGF-1, Cortisol, CGM, real time core body temperature, RHR, overnight HRV (rMSSD), IGF-1, HOMA-IR, sleep architecture, subjective recovery. The purist in us says stick with DAC; that's where the published data lives. Yet the pragmatist says no-DAC + ipamorelin is what thousands of people actually use, and testing it generates more socially relevant data.

@historydefined That’s a real nigga

A man who was born in 1856

@BasedBiohacker Have you looked into selegeline or emsam patches for cognitive enhancement and nueroprotection. I know it’s a hard prescription to get however.

if you ride like lightning you'll crash like thunder

@Nithya_Shrii Depends how serious the job is

Don't ever help anyone you know get a job at your job.. literally ever.

@Polymarket Really calling them “looksmaxxing peptides” smh

BREAKING: FDA to consider easing restrictions on certain "looksmaxxing peptides" favored by RFK Jr.

@ZherkaOfficial @Clav0Updates Completely wrong

This idiot is promoting the greatest gate towards suicide, ayahuasca Many travellers also reported getting ass raped while demon “tripping” for ten hours, later they found out it was not even a spiritual experience, the shaman took advantage of them when they were unconscious. Cannot stand these hippies

Today, we took long-overdue action to restore science, accountability, and the rule of law. In September 2023, the Biden FDA pushed a number of peptides into Category 2 — “Bulk Drug Substances that Raise Significant Safety Risks” — driving a dangerous black market that puts Americans at risk. Now, after nominators withdrew 12 peptides, the FDA will remove them from Category 2 and will bring them to PCAC at its next two meetings, beginning in July—where independent experts will rigorously evaluate each substance on its scientific merits using full clinical, pharmacological, and safety evidence. • BPC-157 • Thymosin beta-4 fragment (LKKTETQ) • Epitalon • GHK-Cu (injectable) • MOTS-c • DSIP (Emideltide) • Dihexa Acetate • Ibutamoren Mesylate • Melanotan II • KPV • Semax (heptapeptide) • Cathelicidin LL-37 This action begins to restore regulated access and will immediately begin shifting demand away from the black market. We will follow the science, enforce the law, and deliver the clarity patients, providers, and pharmacies deserve.

@Timcast Tim remember when you were on Rogan

This is the same as trans shit imo He's hepped up on goofballs and is going to kill himself because he has a mental disorder

@ninoboxer Nino I think if given the opportunity you would blow Trump just like the girls on Epsteins island.

Trump is trolling the Roman Catholic Church… The head of the snake

@MarkHer97461041 @moonchild23580 Fine man you win. If you think “most” rich woman are dating broke men you’re sorely mistaken.

@Americrusader @moonchild23580 "If you think a rich woman is dating a broke man, your (you're) sorely mistaken" *Implying that it never happens and never will happen*

MEN ONLY: be honest: would you date a woman who makes more money than you?

@Argenpoirot Where were these teachers when I was 14

Anamaria Milazzo, de 22 años trabajaba en un colegio de Nueva York, fue arrestada por enviar fotos desnuda a sus alumnos de 14 años.

@covie_93 He’s still the president of the United States

joe rogan criticize trump on his podcast but can't keep that energy in person. Bitch ass behavior.

@Matt_Pinner Nein

One word..

@MarkHer97461041 @moonchild23580 Did you by chance have a recent brain injury? Most low iq people can’t understand statistics so I understand. For example if I said “most people aren’t genderfluid femboys” I would be correct although there are exceptions like yourself.

@Americrusader @moonchild23580 "I'm sure there are many cases of the inverse happening." So you admit your statement was wrong. Because you said it doesn't happen. Dumbass

@MarkHer97461041 @moonchild23580 Yea for real bro your so smart

@Americrusader @moonchild23580 ... Yeah, you're just braindead

@RevRayCistman What ever he’s accused of he did that shit

Free my nephew.

@rittenhouse2a Kyle your getting closer with “Foreign influence”

Round 2: Biggest threat to America

@fitnesscampus_ Caned Ace

🚨 WATCH: Andrew Tate speaks on the fighting in the MAGA movement: “Politics is so ghey…” “Tucker is a hero. Candace is my N*gger. Nick is hilarious.”

America First > MAGA

@MarkHer97461041 @moonchild23580 Generally yes woman do care a lot about there patterns income. I’m sure there are many cases of the the inverse happening but that’s not how statistics work.

@Americrusader @moonchild23580 If you think every rich woman only cares about her partner making as much as she does, you're sorely mistaken. Also, rich women were never mentioned. It said a woman who makes more money than you. Not a woman who's rich and you're poor