Lukasz Bugaj
1.2K posts
Lukasz Bugaj
@BugajLab
Asst. Professor @ Penn Bioengineering. Cell Signaling, optogenetics, synthetic biology, cancer signaling, regenerative medicine, bio-tinkering.
Philadelphia, PA شامل ہوئے Mart 2018
682 فالونگ1.5K فالوورز
Evolution navigated billions of challenges to get to us to where we are today. Directed evolution compresses this to 1D axis.
Imagine if you could sample 200 dimensions at once, with data to boot 📈
First @chorylab PACE preprint on our new system to tackle this: TurboPRANCE👇
Ryan Boileau@bffswithbiology
Aaaand it’s online ahhhhh!!! 🥳🥳 So excited!! The first glimpse of my postdoc work with @chorye @dukecagt. Here, @stefanmgolas and I developed TurboPRANCE, an open-source robotics platform for rapid and scaled phage-assisted continuous evolutions. 🧪Tweetorial party!👇1/n
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Lukasz Bugaj ری ٹویٹ کیا
BE Seminar Series this Thurs w @BugajLab, @pennbioeng “Using Light, Temperature, and Protein Condensation to Understand and Control Cells”
be.mit.edu/our-community/…
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Came in to this lovely surprise today — the lab is 10 years young this summer! 🍾
I’m so grateful to all trainees past and present for getting us to where we are and taking us to a bright and exciting future of #lipidtime #chembio discoveries!
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Lukasz Bugaj ری ٹویٹ کیا
I wrote an Op-Ed about the government's attacks on Harvard. Please share with anybody who thinks these attacks help anybody.
prosyn.org/PhWi74r?h=KyJ1…
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Thank you to the colleagues who created an environment for success, the mentors who shared their wisdom and inspired me (Kris Prather, @geochurch, @WilfredChen1 ), & the amazing students I've had the honor of working with over the last 6.5Y
#tenure
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I am thrilled to share that the first preprint from my lab is now available on bioRxiV! In this study, our team elucidates the role of autocrine ligands in the aberrant behavior of oncogene-driven lung cancer.
biorxiv.org/content/10.110…
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Lukasz Bugaj ری ٹویٹ کیا
Check out our paper, now extensively revised and published in @MolecularCell! This has been a real tour de force led by @stephsansbury and @YSereb and we are very excited about the findings and future potential of this approach
cell.com/molecular-cell…
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Thrilled to join this group of scientist and grateful for the support of @MindPrize in our ambitious goal to change how therapies are delivered for repair of the CNS!
@MITChemE
MIND Prize@MindPrize
PSF is thrilled to share the six winners of our 2025 MIND Prize! We are excited to introduce these forward-thinking scientists from across the country. Please join us in congratulating: pershingsquarephilanthropies.org/news/the-persh…
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WOW👏👏👏 @RepAuchincloss gets it. More of this please!
Rep. Jake Auchincloss 🟧@RepAuchincloss
Basic science is inspired by curiosity, accountable to evidence, and subject to peer review. Politics should have no role.
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I am excited to announce that in March, I will start my lab in the Department of Cancer Biology (@Penn_CBIO) at the University of Pennsylvania Perelman School of Medicine (@PennMedicine). Stevens.bio
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@XiaoyongZhang4 @Penn @pennbioeng I don't see one from you in my inbox Xiaoyong, please send it along again!
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@BugajLab @Penn @pennbioeng Dear professor, I sent you a postdoctoral application. No reply was receive. Have you not received my application? From John Hopkins
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We are hiring postdocs! Projects on 1) probes for remote control of cell death and inflammation, and 2) application in vivo to study inflammation in cancer and therapy. Exciting science in an unparalleled environment @Penn @pennbioeng.
DM or email if interested!
GIF
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Lukasz Bugaj ری ٹویٹ کیا
Geometric packing of tubules in the developing kidney urinary collecting system leads to tissue stiffening and rhythmic mechanical stresses local to nephron-forming niches that synchronize with tubule branching. @HughesLabPenn
nature.com/articles/s4156…
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Thrilled that our work on the functional effects of EML4-ALK assemblies in cancer cells is now published in @NatureComms. Herculean effort through 2.5+ years of peer review by @David_GonzMar and @LeeeRoth. nature.com/articles/s4146…
Lukasz Bugaj@BugajLab
So excited to share our latest on how oncogenes and drugs corrupt cell signal perception, feat. protein condensates, optogenetics, Erk pulses, and drug resistance -- something for everyone! Led by @David_GonzMar with huge assist from @LeeeRoth biorxiv.org/content/10.110…
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Philadelphia, PA 🇺🇸 English
Super cool work of @David_GonzMar and @BugajLab, showing the role of EML4-ALK assemblies in MAPK/ERK signaling, and the potential of targeting apoptotic ERK waves in combination with ALK inhibition
Lukasz Bugaj@BugajLab
Thrilled that our work on the functional effects of EML4-ALK assemblies in cancer cells is now published in @NatureComms. Herculean effort through 2.5+ years of peer review by @David_GonzMar and @LeeeRoth. nature.com/articles/s4146…
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