Rahil Ryder

What SNP variation is sufficient to connect an outbreak strain with its potential environmental source? Check out what we learned from genomic analyses of a Serratia marcescens outbreak. Appreciate the collaborative efforts of all involved! mdpi.com/1660-4601/20/1…

#ConvMut is finally free at the @GISAID .org platform to facilitate vaccine & mAb manufacturers. @lsubissi @RajlabN @MarionKoopmans @SolidEvidence @BenjMurrell @SystemsVirology @tylernstarr @JPWeiland @CorneliusRoemer @ilariacapua @yunlong_cao @Invivyd @moderna_tx H/t @polimi

@GovPressOffice Are these posts also going on the trump social media? I hope so

ALMOST A WEEK IN AND THEY STILL DON'T GET IT

In new study led by @timcyuu, we measure how mutations to H3 flu HA affect cell entry, stability & antibody escape We find pleiotropic effects of mutations on these phenotypes shape evolution: epistasis alleviates cell-entry but not stability constraints biorxiv.org/content/10.110…

Monitoring viral evolution at population scale (in almost real-time) for the first time in the history of virology is leading to unprecedented findings like this

@dfocosi Thank you! Will you be moving to bluesky?

Interested in #BirdFlu ? Follow the @WHO virtual meeting on #H5N1 preparedness on Mar 19. Free registration at this link: who.zoom.us/webinar/regist… Includes epidemiology, antivirals and vaccines (my talk). @PeacockFlu @HelenBranswell @DuckSwabber @MichaelWorobey @EricTopol

@jbloom_lab Thank you for your thorough analysis! Im not familiar with the H3 vs H5 numbering. Do you know where I can get more info on that? Confusing if you are trying to compare mutations & the same mutation is labeled differently. Is there a reason you didn't look at the other segments?

Below is brief analysis of HA mutations in two recent cases of H5N1 influenza in humans w contact w dairy cattle in California. Summary is that while virus continues to evolve, nothing about HA mutations in these human cases is obviously alarming.

@HelenBranswell @PeacockFlu

An #H5 #birdflu infection in a person without a link to dairy cows or poultry is kind of unsettling. But some people I spoke to cautioned me not to get over my skiis on this. That said, this situation needs to be thoroughly investigated & watched. statnews.com/2024/09/06/mis…

Amazing work by the Nextstrain team detailing H5N1 cattle outbreak. nextstrain.org/blog/2024-06-1…

Excited to share our preprint on SARS-CoV-2 recombinants in California. preprints.org/manuscript/202…

@kevinlibuit @Dr_KFO Sequence all the things 🙌

Congrats, @Dr_KFO!! You’ve been pushing things forward ever since stepping foot in public health. Thank you for everything you’ve done for both the field and me personally. Fantastic colleague and friend

I got it too!

Genomics Unit Chief Classification: RESEARCH SCIENTIST SUPERVISOR I (EPIDEMIOLOGY/BIOSTATISTICS) $8,984.00 - $11,196.00# of Positions: 1 Work Location: Sacramento County Telework: Hybrid Job Type: Permanent, Full Time calcareers.ca.gov/CalHrPublic/Jo…

We're looking for a Research Scientist Supervisor I. This position supports the California Department of Public Health’s (CDPH) mission and strategic plan by providing scientific leadership on SARS-CoV-2 and coordinating with partners working on other respiratory viruses.

This recruitment is posted in the Sacramento and Contra Costa County locations. Final Filing Date: 3/28/24 Position Details Job Code #: JC-419501 Position #(s): 581-410-5643-909

@SolidEvidence I'm curious what their reasoning is. I know with cryptic lineages there was the concern of violating patient rights or what not, but I didn't realize there was a concern with not being public health significant. I think you have to push back. A lot of ppl just don't understand.

I'm so tired of public health officials telling me that cryptic lineages are 'outside the scope' of public health. How often does ignoring a problem cause it to go away?

@kevinlibuit @jamesbherrick @CurtisKapsak @strnr @JMUCSM @DGSvirginia @Dr_KFO @SeanW_PHLNGS @dmaccannell @sevinsky @EducatedMicrobe @theiagen Me too!

Career talks are always a blast. Unique opportunity to reflect and give thanks to the people who've played such a significant role in my life. @jamesbherrick @CurtisKapsak @strnr @JMUCSM @DGSvirginia @Dr_KFO @SeanW_PHLNGS @dmaccannell @sevinsky @EducatedMicrobe @theiagen

Joint statement by @UNDP, @UNFPA, @UNICEF, @WFP and WHO on humanitarian supplies crossing into Gaza A first, but limited, shipment of life-saving humanitarian supplies from the United Nations and the Egyptian Red Crescent entered Gaza today on 20 trucks, passing through the Rafah Crossing. It will provide an urgently needed lifeline to some of the hundreds of thousands of civilians, mostly women and children, who have been cut off from water, food, medicine, fuel  and other essentials. But it is only a small beginning and far from enough. More than 1.6 million people in Gaza are in critical need of humanitarian aid. Children, pregnant women and the elderly remain the most vulnerable. Nearly half of Gaza’s population are children. With so much civilian infrastructure in Gaza damaged or destroyed in nearly two weeks of constant bombings, including shelters, health facilities, water, sanitation, and electrical systems, time is running out before mortality rates could skyrocket due to disease outbreaks and lack of health-care capacity. Hospitals are overwhelmed with casualties. Civilians face mounting challenges in accessing essential food supplies. Health facilities no longer have fuel and are running on small amounts they have secured locally. These are expected to run out in the next day or so. Water production capacity is at 5 per cent of normal levels. Pre-positioned humanitarian supplies have already been depleted. Vulnerable people are at greatest risk and children are dying at an alarming rate and being denied their right to protection, food, water and health care. Nearly one-third of the population of Palestine was food insecure before this conflict in Gaza. Today stocks in shops are nearly exhausted and bakeries are closing, while tens of thousands of people are displaced and unable to cook or safely purchase food. We call for a humanitarian ceasefire, along with immediate, unrestricted humanitarian access throughout Gaza to allow humanitarian actors to reach civilians in need, save lives and prevent further human suffering. Flows of humanitarian aid must be at scale and sustained, and allow all Gazans to preserve their dignity. We call for safe and sustained access to water, food, health – including sexual and reproductive health – and fuel, which is necessary to enable essential services. We call for the protection of all civilians and civilian infrastructure in Gaza, including health-care facilities. We call for the protection of humanitarian workers in Gaza who are risking their lives in the service of others. And we call for the utmost respect of international humanitarian law by all parties. Gaza was a desperate humanitarian situation before the most recent hostilities. It is now catastrophic. The world must do more.

Here it is, folks

@RealCheckMarker @SolidEvidence Same!

@SolidEvidence Thank you so much. Can't tell you how often I refer to these!

Updated XBB cheatsheet.